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Xultophy Injection

Written By Dr. Betina Chandolia, MDS, BDS
Reviewed By Dr. Lalit Kanodia, MBA, MD Pharmacology
Last updated on 12 Nov 2024 | 01:10 AM (IST)
Xultophy Injection is a combination medicine used in the treatment of type 2 diabetes mellitus. It is usually given when your blood sugar levels have not been well controlled by using other medications. This medicine works best when used together with diet and exercise.
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General Information

Contains

Liraglutide (3.6mg/1ml)+ Insulin Degludec (100IU)

Marketer

Novo Nordisk India Pvt Ltd

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.
The content is shown in English
Xultophy Injection image
Xultophy Injection image

Product introduction

Xultophy Injection should be used in the dose and duration as prescribed by your doctor. Your doctor or nurse will teach you the correct way of injecting it under the skin. You should use this medicine regularly as per the dose advised to get the most benefit. If you stop taking it your blood sugar levels may rise very high and put you at risk of serious complications. It is only part of a treatment program that should also include a healthy diet, regular exercise, and weight reduction as advised by your doctor. Follow the instructions given by your doctor carefully.

You may experience nasal congestion, sore throat, headache, respiratory tract infection, nausea, and diarrhea. Additionally, you may notice some injection site reactions like pain, swelling or redness. Consult your doctor if these do not resolve or persist for a longer duration. 

Before taking this medicine, inform your doctor if you have any kidney, liver or heart problems. Pregnant or breastfeeding women should also consult their doctor before taking it. Your doctor will check your kidney function tests before starting treatment with it. Avoid excessive alcohol intake while taking it as this may increase the risk of developing some side effects.

Uses of Xultophy Injection

Benefits of Xultophy Injection

Treatment of Type 2 diabetes mellitus
Xultophy Injection is a medicine that works to lower your blood glucose levels. It is given as an injection and your doctor or nurse will train you on the correct way to inject it. Lowering blood glucose levels is an essential part of managing diabetes. If you can control the level you will reduce the risk of getting any of the serious complications of diabetes such as kidney damage, eye damage, nerve problems, and loss of limbs. Taking this medicine regularly along with proper diet and exercise will help you live a normal, healthy life.

Side effects of Xultophy Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Xultophy
  • Headache
  • Nausea
  • Diarrhea
  • Hypoglycemia (low blood glucose level)
  • Nasopharyngitis (inflammation of the throat and nasal passages)
  • Vomiting
  • Decreased appetite
  • Upper respiratory tract infection
  • Injection site bruising

How to use Xultophy Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Xultophy Injection works

Xultophy Injection is a combination of two antidiabetic medicines: Liraglutide and Insulin Degludec. Liraglutide helps your body make more insulin during meals and lowers the amount of sugar produced in your body. Insulin Degludec works like your body's natural insulin. It facilitates reuptake of glucose in muscle and fat cells and also blocks release of glucose from the liver. Together, the two medicines provide consistent, all-day sugar control.

Quick tips

  • Xultophy Injection is used along with diet and exercise to lower blood sugar in adults with type 2 diabetes.
  • Take it at the same time each day with or without food.
  • It is injected under the skin of your thigh, upper arm or stomach. Do not inject into a muscle or vein.
  • Injection sites must be rotated to prevent hard lumps from developing at one site.
  • Check the pen label each time to make sure you are using the correct medicine. Monitor your blood sugar level regularly while you are taking this medicine. 
  • Hypoglycemia (low blood sugar level) may occur. Always carry some sugary food with you in case you experience symptoms such as cold sweats, cool pale skin, tremor, and anxious feeling.
  • Do not drive or operate heavy machinery, until you know how Xultophy Injection affects you.
  • Do not drink alcohol or take other medicines that contain alcohol while taking this medicine.
  • Do not share your pen with other people, even if the needle has been changed to avoid giving or getting serious infections.

Safety advice

Alcohol

Alcohol

UNSAFE
It is unsafe to consume alcohol with Xultophy Injection.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Xultophy Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Xultophy Injection during breastfeeding is not available. Please consult your doctor.
Driving

Driving

CAUTION
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Xultophy Injection should be used with caution in patients with kidney disease. Dose adjustment of Xultophy Injection may be needed. Please consult your doctor.
Liver

Liver

CAUTION
Xultophy Injection should be used with caution in patients with liver disease. Dose adjustment of Xultophy Injection may be needed. Please consult your doctor.
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Fact Box

Habit Forming

No

Therapeutic Class

ANTI DIABETIC

Related lab tests

Glucose - Fasting Blood

Glucose - Postprandial Blood

Glycosylated Hemoglobin

References

  1. Insulin Degludec+Liraglutide. Bagsværd, Denmark: Novo Nordisk. [Accessed 25 Apr. 2019] (online) Available from:
  2. Liraglutide. Bagsvaerd, Denmark: Novo Nordisk A/S; 2010. [Accessed 28 Jan. 2019] (online) Available from:
  3. Insulin degludec injection. Bagsvaerd, Denmark: Novo Nordisk A/S; 2015 [revised Dec. 2016]. [Accessed 13 Mar. 2019] (online) Available from:
  4. Insulin degludec and liraglutide injection [Prescribing Information]. Bagsvaerd, Denmark: Novo Nordisk A/S; 2016. [Accessed 14 Aug. 2024] (online) Available from:
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Patient concerns

Diabetes mellitus type 2 ,thirst

Dr. Sanjay Bhatt
Dr. Sanjay Bhatt
Physician
A person can control his or her sugar levels by doing regular exercise and walk or regular aerobic exercises at least 30 to 45 minutes per day.MEDICAL NUTRITIONAL THERAPY THAT IS TO MAINTAIN CALORIES INTAKE AS PER BMI .TAKE HELP OF DIABETIC EDUCATOR. VISIT YOUR DOCTOR AND FOLLOW ALL WHAT DOCTOR SUGGESTED.IN TIME ALL ROUTINE INVESTIGATIONS SHOULD BE DONE.you should not treat it as disease but a start of a healthy life.Uncontrolled sugar levels for long time leads to lower limb weakness which is neuropathy and which is followed by foot ulcers and other complications like kidney or heart problems .online prescription is not allowed without seeing pt.so contact doctor nearby for any change or dose adjustment or visit my clinic at gurgaon sector 52 RdCity snergy multi speciality clinic near SRS MARKET

Diabetes mellitus type 2 required only ayurvedic medicine

Dr. Sanjay Bhatt
Dr. Sanjay Bhatt
Physician
Go for allopathic medicine
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Novo Nordisk India Pvt Ltd
Address: Plot No.32, 47-50, EPIP Area, Whitefield, Bangalore - 560 066

Vendor Details

Country of origin: Denmark

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