XYNOLUBE 0.1% DROPS
Written By Dr. Betina Chandolia, MDS, BDS
Reviewed By Dr. Ashish Ranjan, MD (Pharmacology), MBBS
Last updated on 31 Oct 2024 | 01:10 AM (IST)
XYNOLUBE 0.1% DROPS is a medicine used to treat nasal congestion (blocked nose) caused by the common cold or flu, hay fever, and other allergies. It narrows blood vessels in your nose to relieve nasal congestion and blockage.
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General Information
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Product introduction
XYNOLUBE 0.1% DROPS should be used as you have been advised by your doctor. It provides only temporary relief but do not use it more often or for longer than recommended. Normally you should blow your nose gently before using it, keep one nostril closed while applying the medicine into the other and then sniff hard to make sure it reaches deep into the nose. Then repeat for the other nostril. It provides relief very quickly and can last for several hours. If you use this medicine too often or for too long, it may worsen your symptoms rather than improve them.
The most common side effects are irritation or discomfort to the nose and sneezing. These are usually mild but if they bother you or do not go away, your doctor may be able to suggest ways of preventing or reducing them.
It is generally a safe medicine but, before taking it, talk to your doctor about any health problems you have such as heart problems or high blood pressure (hypertension) or overactive thyroid gland or glaucoma or prostate enlargement. Let your doctor know about any other medicines you are taking to make sure you are safe. Ask your doctor for advice before using this medicine if you are pregnant or breastfeeding.
The most common side effects are irritation or discomfort to the nose and sneezing. These are usually mild but if they bother you or do not go away, your doctor may be able to suggest ways of preventing or reducing them.
It is generally a safe medicine but, before taking it, talk to your doctor about any health problems you have such as heart problems or high blood pressure (hypertension) or overactive thyroid gland or glaucoma or prostate enlargement. Let your doctor know about any other medicines you are taking to make sure you are safe. Ask your doctor for advice before using this medicine if you are pregnant or breastfeeding.
Uses of Xynolube Drop
- Nasal congestion (blocked nose)
Side effects of Xynolube Drop
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Xynolube
- Dryness
- Irritation
- Sneezing
How to use Xynolube Drop
Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a marked dropper and take it as directed. XYNOLUBE 0.1% DROPS may be taken with or without food, but it is better to take it at a fixed time.
How Xynolube Drop works
XYNOLUBE 0.1% DROPS is a decongestant. It works by narrowing the small blood vessels which provides temporary relief from inflammation (redness and swelling) and discomfort.
Quick tips
- It works right away and each dose provides relief for up to 12 hours.Â
- XYNOLUBE 0.1% DROPS can make nasal congestion worse if used for more than 3 or 4 days in a row (called rebound congestion).
- The right way to use the nasal spray:
- Shake the bottle before using the medicine.Â
- Clean your nose thoroughly before using the medicine.
- Insert the bottle tip into one nostril and close the other nostril.Â
- Direct the spray towards the sides of your nostril, away from the cartilage dividing the two sides of your nose.
- Breathe out gently through your mouth and repeat the same process for the other nostril.
- Avoid deep breathing as it will cause medication to go back to the throat and make it less effective.
- Do not share the bottle with anyone else so that you do not spread germs.
- It works right away and each dose provides relief for up to 12 hours.Â
- The right way to use the nasal spray:
- Shake the bottle before using the medicine.Â
- Clean your nose thoroughly before using the medicine.
- Insert the bottle tip into one nostril and close the other nostril.Â
- Direct the spray towards the sides of your nostril, away from the cartilage dividing the two sides of your nose.
- Breathe out gently through your mouth and repeat the same process for the other nostril.
- Avoid deep breathing as it will cause medication to go back to the throat and make it less effective.
- Do not share the bottle with anyone else so that you do not spread germs.
- XYNOLUBE 0.1% DROPS can make nasal congestion worse if used for more than 3 or 4 days in a row (called rebound congestion).
Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with XYNOLUBE 0.1% DROPS. Please consult your doctor.

Pregnancy
CONSULT YOUR DOCTOR
XYNOLUBE 0.1% DROPS may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding
SAFE IF PRESCRIBED
XYNOLUBE 0.1% DROPS is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
To reduce the amount of XYNOLUBE 0.1% DROPS that reaches the breastmilk, remove the excess solution with an absorbent tissue.
To reduce the amount of XYNOLUBE 0.1% DROPS that reaches the breastmilk, remove the excess solution with an absorbent tissue.

Driving
SAFE
XYNOLUBE 0.1% DROPS does not usually affect your ability to drive.

Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of XYNOLUBE 0.1% DROPS in patients with kidney disease. Please consult your doctor.

Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of XYNOLUBE 0.1% DROPS in patients with liver disease. Please consult your doctor.
Frequently asked questions
Treatment with XYNOLUBE 0.1% DROPS does not cause mental addiction. However, patients may get physically addicted such that they may feel an urge to use XYNOLUBE 0.1% DROPS. Hence, it should only be used at prescribed doses for the prescribed duration as advised by your doctor.
No, XYNOLUBE 0.1% DROPS is not a steroid or an antihistamine. It belongs to a class of medications called adrenergic medicines that are used as nasal decongestants (to relieve congestion of the nose).
XYNOLUBE 0.1% DROPS is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.
There are no such reports which suggest occurrence of side effects such as cataract, insomnia (inability to sleep) or drowsiness during treatment with XYNOLUBE 0.1% DROPS. However, XYNOLUBE 0.1% DROPS can raise blood pressure when taken with medicines that are used to treat depression, like selegiline and moclobemide. It can also decrease the effect of medicines used to treat blood pressure. Hence, patients should consult doctors regarding the possible side effects and drug interactions.
XYNOLUBE 0.1% DROPS should not be taken simultaneously with Benadryl (diphenhydramine)/phenylephrine/pseudoephedrine. Consult your doctor before using any other medicine with XYNOLUBE 0.1% DROPS.
Fact Box
Chemical Class
Imidazole Derivative
Habit Forming
No
Therapeutic Class
OPHTHAL
Action Class
Sympthatomimmetics- alpha 1 (Nasal)
References
- Biaggioni I, Robertson D. Adrenoreceptor Agonists & Sympathomimetic Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 140.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1041-42.
- Drugs.com. Oxymetazoline. [Accessed 01 Apr. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 01 Apr. 2019] (online) Available from:
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Patient concerns
Nasal congestion, cough, vomiting, ear blocked and pain
Dr. Gopal Samdani
Paediatrics
There are many underlying causes of your symptoms. Different cause needs different treatment. Specific treatment cannot be given unless we establish exact underlying cause. Final and perfect diagnosis cannot be done without doing clinical examination of child. Please consult me or any other Paediatrician. will take detail history and will examine your child in detail. At time may ask you relevant investigations if necessary. All information will be used to determine exact underlying cause of problem. Depending upon cause will prescribe you treatment.
Nose blocked unable to breathe. Used nasal clear still blocked
Dr. Vijay Verma
ENT
Can be due to deviated septum Visit ent specialist
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Marketer details
Name: Ajanta Pharma Ltd
Address: Ajanta House, Charkop, Kandivli West, Mumbai 400 067, India
Address: Ajanta House, Charkop, Kandivli West, Mumbai 400 067, India
Vendor Details
Country of origin: India
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