Yondelis Injection

Reviewed By Dr. Lalit Kanodia, MBA, MD Pharmacology

Last updated on 11 Nov 2024 | 01:04 AM (IST)

Yondelis Injection is used in the treatment of some kinds of cancers. It is used in patients with advanced soft tissue sarcoma when previous medicines have been unsuccessful. It is also used with other medicines as part of combination therapy to treat ovarian cancer that has come back.

Genuine

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Prescription

required

MRP ₹133300

General Information

Contains

Trabectedin (1mg)

Marketer

Janssen Pharmaceuticals

Storage

Store below 30°C

The content is shown in English

Product introduction

Yondelis Injection is given as an injection under the medical supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include headache, fatigue, vomiting, weakness and increased liver enzyme. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver and kidney. Generally, avoid alcohol consumption while on treatment.

Before taking it, tell your doctor if have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using.This medicine is not recommended during pregnancy or while breastfeeding. Use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Yondelis Injection

Soft tissue sarcoma

Benefits of Yondelis Injection

Soft tissue sarcoma
Soft tissue sarcoma is a type of sarcoma that develops in tissues such as bone and muscles. Yondelis Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. Follow your doctor’s instructions carefully and let your doctor know if any of the side effects bother you.

Side effects of Yondelis Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Yondelis

Headache
Fatigue
Vomiting
Weakness
Nausea
Increased liver enzymes
Low blood platelets
Increased creatine phosphokinase (CPK) level in blood
Decreased white blood cell count (neutrophils)
Decreased appetite
Constipation

How to use Yondelis Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Yondelis Injection works

Trabectedin belongs to class of drugs called alkylating agents. It works by sticking to the DNA in cells and damaging it. This stops the cancer cells growing and multiplying.

Quick tips

Yondelis Injection is given as an intravenous infusion (IV infusion) under the supervisión of a doctor.
Do not skip any dose and complete the course as suggested by your doctor.
Use an effective method of birth control to avoid pregnancy while taking this medication.
Inform your doctor if you notice yellowing of eyes or skin, dark urine, muscle pain and skin rash.
Your doctor may get regular blood tests done to monitor your blood cell count, platelet count and liver function.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Yondelis Injection.

Pregnancy

CONSULT YOUR DOCTOR

Information regarding the use of Yondelis Injection during pregnancy is not available. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Yondelis Injection during breastfeeding is not available. Please consult your doctor.

Driving

UNSAFE

Yondelis Injection may cause side effects which could affect your ability to drive.
Yondelis Injection may make you feel tired and experience a loss of strength which may affect your ability to drive.

Kidney

CAUTION

Yondelis Injection should be used with caution in patients with kidney disease. Dose adjustment of Yondelis Injection may be needed. Please consult your doctor.

Liver

CAUTION

Yondelis Injection should be used with caution in patients with liver disease. Dose adjustment of Yondelis Injection may be needed. Please consult your doctor.

Fact Box

Chemical Class

Benzazocine Derivative

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Anticancer-others

References

Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1719-20.
Trabectedin. Hertford, Herts: Immedica; 2007 [revised Jun. 2018]. [Accesed 27 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Janssen Pharmaceuticals
Address: Johnson & Johnson Private Limited., 501 Arena Space, Behind Majas Bus Depot, Off Jogeshwari Vikhroli Link Road, Jogeshwari (E), Mumbai 400 060

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Provide right medicines

Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose

In accordance with the law

Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945