Zavedos 25mg Capsule

Idarubicin (25mg)

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Zavedos 25mg Capsule is used in the treatment of some kinds of blood cancer (leukemia). It may be also used to treat other conditions, as determined by the doctor. It is sometimes used with certain other medicines as part of combination chemotherapy.

Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Ashish Ranjan, MD (Pharmacology), MBBS,
Last updated on 09 Nov 2024 | 01:03 AM (IST)

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1 Capsule

Gurgaon

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Free Return

within 7 days

Expiry after

Sep, 2026

General Information

Contains

Idarubicin (25mg)

Marketer

Pfizer Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Zavedos 25mg Capsule can be taken with or without food, but try to have it at the same time every day to get most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include vomiting, nausea, infection, hair loss, and fever. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.

Before taking it, tell your doctor if have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Zavedos Capsule

Blood cancer (Acute lymphocytic leukemia)

Benefits of Zavedos Capsule

Blood cancer (Acute lymphocytic leukemia)
Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body's ability to fight infection. Zavedos 25mg Capsule kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Side effects of Zavedos Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Zavedos

Vomiting
Nausea
Infection
Hair loss
Fever
Increased liver enzymes
Peripheral neuropathy (tingling and numbness of feet and hand)
Stomatitis (Inflammation of the mouth)
Bleeding
Myelosuppression
Seizure

How to use Zavedos Capsule

Take this medicine in the dose and duration as advised by your doctor. Zavedos 25mg Capsule may be taken with or without food, but it is better to take it at a fixed time.

How Zavedos Capsule works

Zavedos 25mg Capsule is an anti-cancer medication. It works by suppressing the activity of an enzyme (topoisomerase II) involved in DNA multiplication of the cancer cells. It also forms harmful chemicals (free radicals) which cause DNA damage. This slows the growth of cancer cells and eventually kills them.

Quick tips

Zavedos 25mg Capsule should be taken with or without food but at the same time every day.
Do not skip any dose and complete the course as suggested by your doctor.
Use an effective method of birth control to avoid pregnancy while taking this medication.
Your doctor may get regular blood tests done to monitor your blood uric level, liver function, blood cell count in your blood.
Inform your doctor if you experience dizziness, fever, shortness of breath and itchy rash.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Zavedos 25mg Capsule. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Zavedos 25mg Capsule is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

UNSAFE

Zavedos 25mg Capsule is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

UNSAFE

Zavedos 25mg Capsule may cause side effects which could affect your ability to drive.
Special care should be taken if it is essential that you drive while undergoing treatment especially if you are lacking strength or are in a debilitated condition.

Kidney

CAUTION

Zavedos 25mg Capsule should be used with caution in patients with kidney disease. Dose adjustment of Zavedos 25mg Capsule may be needed. Please consult your doctor.
Get kidney function tests done before the start of this medicine.

Liver

CAUTION

Zavedos 25mg Capsule should be used with caution in patients with liver disease. Dose adjustment of Zavedos 25mg Capsule may be needed. Please consult your doctor.
Get liver function tests done before the start of this medicine.

Frequently asked questions

Is Zavedos 25mg Capsule a vesicant?

Zavedos 25mg Capsule can cause inflammation of the vein in which it is administered; and irritation and ulceration of surrounding tissue, if leakage occurs at the site of intravenous administration.

What is Zavedos 25mg Capsule used for?

Zavedos 25mg Capsule is used in the treatment of acute myeloid leukaemia (a type of cancer of the white blood cells) in combination with other medications and breast cancer in advance stage after failure with other medications.

How does Zavedos 25mg Capsule work?

Zavedos 25mg Capsule acts by inhibiting the growth of cancer cells.

Fact Box

Chemical Class

Anthracycline Derivative

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Anticancer-others

Related lab tests

Complete Blood Count

Peripheral Smear Examination

References

Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 952.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 686-87.
Idarubicin. Ramsgate Road Sandwich: Pfizer Limited; 2002 [revised Aug. 2018]. [Accessed 27 Mar. 2019] (online) Available from:
National Cancer Institute. Idarubicin. [Accessed 27 Mar. 2019] (online) Available from:

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Pfizer Ltd
Address: The Capital, 1802, 18th Floor , Plot No. C-70, ‘G’ Block , Bandra Kurla Complex, Bandra East , Mumbai – 400051.

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Zavedos 25mg Capsule. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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