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Zoldex 12.5 Tablet PR

Written By Dr. Swati Mishra, BDS
Reviewed By Dr. Khushbu Goel, DM, MD
Last updated on 05 Nov 2024 | 01:06 AM (IST)
Zoldex 12.5 Tablet PR is used for short-term treatment of insomnia. It reduces sleep onset time and frequent awakening at night. This medicine improves sleep maintenance and therefore ensures sound sleep.
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Zoldex 12.5 Tablet PR image
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Product introduction

Zoldex 12.5 Tablet PR should be taken on an empty stomach, preferably just before going to bed. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor as it is habit-forming. Do not stop taking it suddenly without talking to your doctor as it may worsen your symptoms.

Some common side effects of this medicine include memory loss, hallucinations, agitation, headache, vertigo, diarrhea, nausea, vomiting, and back pain. It may also cause fatigue, stomach pain, double vision, and depression. However, these are temporary and resolve on their own after some time. Please consult your doctor if these bother you or do not away.

Zoldex 12.5 Tablet PR also causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you, and do not take alcohol with it as it may worsen the dizziness. Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, hallucinations, or suicidal thoughts while taking this medicine.

Before taking Zoldex 12.5 Tablet PR, inform your doctor about all other medicines that you are taking, so that your doctor can advise if taking this medicine is right for you. Consult your doctor before taking this medicine if you are suffering from any liver or kidney problems. You should avoid smoking and alcohol while using this medicine. Pregnant and breastfeeding mothers should not use this medicine. However, if the need arises, please consult your doctor before using it.

Uses of Zoldex Tablet PR

Benefits of Zoldex Tablet PR

Treatment of Insomnia
Insomnia is a common sleep disorder in which there is difficulty in falling or staying asleep at night. Zoldex 12.5 Tablet PR helps treat insomnia as well as improves sleep quality. Zoldex 12.5 Tablet PR works by slowing activity in the brain to allow sleep. This helps you relax and feel more energetic. It also helps you concentrate better and improves your quality of life.
With Zoldex 12.5 Tablet PR, your sleep problems should improve within 7 to 10 days. Apart from this, it is advisable to make some lifestyle changes to sleep better.

Side effects of Zoldex Tablet PR

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Zoldex
  • Dizziness
  • Sleepiness
  • Headache
  • Nausea
  • Stomach pain
  • Memory loss
  • Vertigo
  • Vomiting
  • Back pain
  • Agitation
  • Double vision
  • Depression

How to use Zoldex Tablet PR

Use it as advised by your doctor or check the label for directions before use. Zoldex 12.5 Tablet PR is to be taken empty stomach.

How Zoldex Tablet PR works

Zoldex 12.5 Tablet PR belongs to a group of medicines called non-benzodiazepine hypnotics. It has hypnotic, sedative, and anticonvulsant (manages fits) properties. It works by binding of the GABAA receptor chloride channel macromolecular complex (a chemical messenger) that slows the activity of the nerve cells in the brain and helps fall asleep.

Quick tips

  • Your doctor has prescribed Zoldex 12.5 Tablet PR to help you fall asleep faster and sleep for longer.
  • It is best taken without food as a high-fat meal can reduce its absorption and effect. 
  • Take it 30 to 45 minutes before bedtime and only when you have time to sleep for at least 7 hours.
  • It makes you feel dizzy next morning. Don't drive or do anything requiring concentration until you know how it affects you.
  • It does not affect total sleep time. However,  it reduces sleep onset time and frequent awakening at night.
  • Never share your medication with any other person who also has a sleep problem.
  • Inform your doctor if your sleep doesn’t improve after 7 to 10 days of treatment.
  • Stop taking medication and inform your doctor If you experience sleep driving or memory loss.
  • Do not stop taking medication suddenly as it may lead to anxiety, mood changes, and restlessness. 

Safety advice

Alcohol

Alcohol

UNSAFE
Zoldex 12.5 Tablet PR may cause excessive drowsiness with alcohol.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Zoldex 12.5 Tablet PR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding

Breast feeding

SAFE IF PRESCRIBED
Zoldex 12.5 Tablet PR is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving

Driving

UNSAFE
Zoldex 12.5 Tablet PR may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

SAFE IF PRESCRIBED
Zoldex 12.5 Tablet PR is safe to use in patients with kidney disease. No dose adjustment of Zoldex 12.5 Tablet PR is recommended.
However, inform your doctor if you have any kidney disease.
Liver

Liver

CAUTION
Zoldex 12.5 Tablet PR should be used with caution in patients with liver disease. Dose adjustment of Zoldex 12.5 Tablet PR may be needed. Please consult your doctor.
Zoldex 12.5 Tablet PR is generally started at a low dose in patients with mild to moderate liver disease and is not recommended in patients with severe liver disease.

Frequently asked questions

Zoldex 12.5 Tablet PR produces a calming effect on the brain and induces sleep. This calming effect may be perceived as pleasant or feeling high by some individuals. On prolonged use, Zoldex 12.5 Tablet PR may also make an individual dependent such that they are not be able to sleep or function normally without taking it.
Yes, Zoldex 12.5 Tablet PR has abuse potential. However, it is more commonly seen in patients with a history of drug abuse, alcohol consumption, and drug addiction. Therefore, doctors should carefully take history of drug abuse from the patient. Moreover, patients with a history of drug abuse or addiction should be closely monitored during Zoldex 12.5 Tablet PR therapy.
No drug-drug interactions have been found Zoldex 12.5 Tablet PR taken with prednisone. However always consult with your doctor before taking these medicines together.
Zoldex 12.5 Tablet PR is used to treat insomnia, which may help ease anxiety in some patients, although doctors do not prescribe Zoldex 12.5 Tablet PR for anxiety alone because it does not work in the same manner as other sedatives anti-anxiety drugs
The symptoms of Zoldex 12.5 Tablet PR overdose include drowsiness, confusion, problems with coordination, floppy muscles, slow or difficult breathing, and even coma (loss of consciousness for a period of time).
Zoldex 12.5 Tablet PR can make you drowsy during the daytime and also decrease your mental alertness. Therefore, you should not drive or operate heavy machinery until and unless you know how Zoldex 12.5 Tablet PR affects you. Do not drink alcohol while you are taking Zoldex 12.5 Tablet PR. Alcohol can make the side effects of Zoldex 12.5 Tablet PR even worse.
You should not take Zoldex 12.5 Tablet PR if you are allergic to it or any of its ingredients. You should also avoid Zoldex 12.5 Tablet PR if you have a history of depression, mental illness, or suicidal thoughts. A person having a history of drug or alcohol abuse or addiction, having kidney or liver disease, having a lung disease or breathing problems should avoid Zoldex 12.5 Tablet PR. Also, its consumption is not recommended if you are pregnant, planning to become pregnant, or breastfeeding.
No, do not take Zoldex 12.5 Tablet PR with or shortly after a heavy, high-fat meal. Zoldex 12.5 Tablet PR may not work well if it is taken with high-fat foods.
Zoldex 12.5 Tablet PR is used for short-term (2-4 weeks) treatment of insomnia (difficulty falling asleep). It should be taken exactly as prescribed by the doctor. The dose and duration of treatment should not be exceeded else it may lead to dependence (addiction towards medicine).
Yes, dry mouth is a common side effect of Zoldex 12.5 Tablet PR, whereas weight gain is less common with Zoldex 12.5 Tablet PR. If you experience weight gain, it could be due to increased appetite.
Zoldex 12.5 Tablet PR starts working as soon as you take it and may make you very sleepy. You may remain sleepy for some time after you take the medication. Plan to go to bed right after you take Zoldex 12.5 Tablet PR and to stay in bed for 7 to 8 hours. Do not take Zoldex 12.5 Tablet PR if you will be unable to go to bed right away and remain asleep for 7 to 8 hours after taking the medication.
Do not stop taking Zoldex 12.5 Tablet PR without talking to your doctor. If you suddenly stop taking Zoldex 12.5 Tablet PR, you may experience withdrawal symptoms such as unpleasant feelings, stomach and muscle cramps, vomiting, sweating, shakiness, and rarely, seizures.
You can improve your sleep by avoiding caffeine and nicotine, especially late in the day. Avoid exercise during the four hours before bedtime; daily exercise is beneficial to sleep, but can interfere if done close to bedtime. Avoid large meals in the evening. Avoid taking naps. Go to sleep and wake up at the same time each day. Keep the bedroom as dark as possible and maintain a comfortable temperature. Set aside a time to relax before bed and use relaxation techniques.
Insomnia is a common sleep disorder. People with insomnia experience trouble in falling asleep, staying asleep, or both. As a result, they may get too little sleep or have poor-quality sleep, and they may not feel refreshed after waking up.
Insomnia can be of two types- primary or secondary. In primary insomnia, the cause is not known. It can be triggered by life-style changes including long-lasting stress and emotional upset. Whereas, secondary insomnia can be caused due to various reasons such as certain medical conditions (depression, anxiety, post-traumatic stress disorder, Alzheimer's disease, and Parkinson's disease), medicines, sleep disorders, and substances (caffeine and other stimulants, tobacco and other nicotine products, and alcohol).

Fact Box

Chemical Class

Imidazopyridine Derivative

Habit Forming

Yes

Therapeutic Class

NEURO CNS

Action Class

Non-benzodiazepine hypnotics (Z Compounds)

References

  1. Mihic SJ, Harris RA. Hypnotics and Sedatives. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 467-68.
  2. Stahl SM, editor. Zolpidem. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 751-54.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1519-20.
  4. Drugs.com. Zolpidem. [Accessed 19 Mar. 2019] (online) Available from:
  5. Chaves RG, Lamounier JA, et al. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 19 Mar. 2019] (online) Available from:
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Patient concerns

Best medicine for curing insomnia

Dr. Anuneet Sabharwal
Dr. Anuneet Sabharwal
Psychiatry
Depends on the cause of insomnia

I can not sleep more than 5 hours,i had thyroid problem,for that thyroid .75 is taking,also taking asomax for b p problem though it is 130/90, my main problem sins is I can't sleep more than 5 hours ,

Dr. Sfurti Mann
Dr. Sfurti Mann
Diabetology
Consult a psychiatrist for insomnia
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Dyso Healthcare Pvt Ltd
Address: Sisona,Nr.Bhagwanpur Roorkee -247661 (uk)

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Country of origin: India
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