Zolgas 40 Tablet
Written By Dr. Anuj Saini, MMST, MBBS
Reviewed By Dr. Ashish Ranjan, MD (Pharmacology), MBBS
Last updated on 11 Nov 2024 | 01:04 AM (IST)
Zolgas 40 Tablet is used to treat conditions related to excessive stomach acid production, such as gastroesophageal reflux disease (GERD), peptic ulcer disease, and Zollinger-Ellison syndrome. It reduces the amount of acid produced in the stomach and provides relief from symptoms and promotes healing.
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General Information
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Product introduction
Zolgas 40 Tablet can also be used to prevent stomach ulcers caused by certain medications, such as nonsteroidal anti-inflammatory drugs (NSAIDs). Take the medicine as per your doctor's prescription. The dose will depend on what you are being treated for, but it is usually the lowest dose for the shortest time that is needed to treat your condition. It is usually taken on an empty stomach, preferably in the morning or at least 1 hour prior to meal. Continue taking the medicine even if your symptoms disappear until the doctor say it is okay to stop. If you are taking this medicine for a long time, your doctor may carry out regular tests to check your levels of magnesium which can fall with this medicine.
Common side effects include headache, constipation or diarrhea, stomach pain, and feeling or being sick. These tend to be mild but talk to your doctor if they bother you or do not go away. The risk of side effects may increase the longer you take this medicine. You may be more likely to have a broken bone if you take it for a long time. It is best to avoid foods that seem to make your symptoms worse, such as rich, spicy, and fatty foods. Cutting down on caffeinated drinks, such as tea, coffee, and cola, as well as alcohol may also help.
This medicine is not suitable for some people. Before taking this medicine, you need to tell your doctor if you have severe liver problems, are taking medicines for HIV, have had an allergic reaction to similar medicines in the past, or have osteoporosis. Alcohol does not interfere with the way Zolgas 40 Tablet works. However, drinking alcohol makes your stomach produce more acid than normal. This medicine can make you feel dizzy, sleepy, or affect your vision. If this happens, do not drive, cycle, or use machinery or tools until you feel better. It is not usually recommended during pregnancy and breastfeeding.
Common side effects include headache, constipation or diarrhea, stomach pain, and feeling or being sick. These tend to be mild but talk to your doctor if they bother you or do not go away. The risk of side effects may increase the longer you take this medicine. You may be more likely to have a broken bone if you take it for a long time. It is best to avoid foods that seem to make your symptoms worse, such as rich, spicy, and fatty foods. Cutting down on caffeinated drinks, such as tea, coffee, and cola, as well as alcohol may also help.
This medicine is not suitable for some people. Before taking this medicine, you need to tell your doctor if you have severe liver problems, are taking medicines for HIV, have had an allergic reaction to similar medicines in the past, or have osteoporosis. Alcohol does not interfere with the way Zolgas 40 Tablet works. However, drinking alcohol makes your stomach produce more acid than normal. This medicine can make you feel dizzy, sleepy, or affect your vision. If this happens, do not drive, cycle, or use machinery or tools until you feel better. It is not usually recommended during pregnancy and breastfeeding.
Uses of Zolgas Tablet
- Acidity
- Gastroesophageal reflux disease (Acid reflux)
- Peptic ulcer disease
- Treatment of Zollinger-Ellison syndrome
Benefits of Zolgas Tablet
Treatment of Zollinger-Ellison syndrome
Zollinger-Ellison syndrome is a rare disorder where excessive stomach acid production leads to multiple peptic ulcers. Symptoms include abdominal pain, diarrhea, and heartburn. Zolgas 40 Tablet By reducing the production of stomach acid, it helps alleviate symptoms such as abdominal pain, heartburn, and diarrhea. Esomeprazole also aids in the healing of peptic ulcers, which are common in this condition. By controlling the excessive acid secretion associated with Zollinger-Ellison syndrome, esomeprazole helps improve the overall digestive health and prevents complications such as gastrointestinal bleeding.
Zollinger-Ellison syndrome is a rare disorder where excessive stomach acid production leads to multiple peptic ulcers. Symptoms include abdominal pain, diarrhea, and heartburn. Zolgas 40 Tablet By reducing the production of stomach acid, it helps alleviate symptoms such as abdominal pain, heartburn, and diarrhea. Esomeprazole also aids in the healing of peptic ulcers, which are common in this condition. By controlling the excessive acid secretion associated with Zollinger-Ellison syndrome, esomeprazole helps improve the overall digestive health and prevents complications such as gastrointestinal bleeding.
Side effects of Zolgas Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Zolgas
- Headache
- Dryness in mouth
- Nausea
- Abdominal pain
- Constipation
- Flatulence
- Diarrhea
How to use Zolgas Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zolgas 40 Tablet is to be taken empty stomach.
How Zolgas Tablet works
Zolgas 40 Tablet is a proton pump inhibitor (PPI). It works by reducing the amount of acid in the stomach which helps in relief of acid related indigestion and heartburn.
All substitutes for Zolgas 40 Tablet
For information purposes only. Consult a doctor before taking any medicine.
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Quick tips
- It is a well-tolerated medicine and provides relief for a long time.
- Some healthy tips to prevent acidity from happening:
- Avoid excessive intake of carbonated beverages/soft drinks, citrus juices, fried food, caffeinated beverages like tea and coffee.
- Avoid alcohol and smoking.
- Avoid eating late at night or before bedtime.
- Inform your doctor if you get watery diarrhea, fever or stomach pain that does not go away.
- Long-term use of Zolgas 40 Tablet can cause weak bones and a deficiency of minerals such as magnesium. Take adequate dietary intake of calcium and magnesium or their supplements as prescribed by your doctor.
- Consult your doctor right away if you develop decreased urination, edema (swelling due to fluid retention), lower back pain, nausea, fatigue, and rash or fever. These could be signs of a kidney problem.
- Zolgas 40 Tablet should be taken 1 hour before a meal, preferably in the morning.
- It is a well-tolerated medicine and provides relief for a long time.
- Some healthy tips to prevent acidity from happening:
- Avoid excessive intake of carbonated beverages/soft drinks, citrus juices, fried food, caffeinated beverages like tea and coffee.
- Avoid alcohol and smoking.
- Avoid eating late at night or before bedtime.
- Inform your doctor if you get watery diarrhea, fever or stomach pain that does not go away.
- Inform your doctor if you do not feel better after taking it for 14 days as you may be suffering from some other problem that needs attention.
- Long-term use of Zolgas 40 Tablet can cause weak bones and a deficiency of minerals such as magnesium. Take adequate dietary intake of calcium and magnesium or their supplements as prescribed by your doctor.
- Consult your doctor right away if you develop decreased urination, edema (swelling due to fluid retention), lower back pain, nausea, fatigue, and rash or fever. These could be signs of a kidney problem.
Safety advice

Alcohol
CAUTION
Caution is advised when consuming alcohol with Zolgas 40 Tablet. Please consult your doctor.

Pregnancy
CONSULT YOUR DOCTOR
Information regarding the use of Zolgas 40 Tablet during pregnancy is not available. Please consult your doctor.
Caution should be exercised when Zolgas 40 Tablet is administered to pregnant women.
Caution should be exercised when Zolgas 40 Tablet is administered to pregnant women.

Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Zolgas 40 Tablet during breastfeeding is not available. Please consult your doctor.
Caution should be exercised when Zolgas 40 Tablet is administered to breastfeeding women.
Caution should be exercised when Zolgas 40 Tablet is administered to breastfeeding women.

Driving
UNSAFE
Zolgas 40 Tablet may cause side effects which could affect your ability to drive.
In rare cases, Zolgas 40 Tablet may cause dizziness and blurred vision, do not drive or use machines if you experience such symptoms.
In rare cases, Zolgas 40 Tablet may cause dizziness and blurred vision, do not drive or use machines if you experience such symptoms.

Kidney
SAFE IF PRESCRIBED
Zolgas 40 Tablet is safe to use in patients with kidney disease. No dose adjustment of Zolgas 40 Tablet is recommended.
However, due to lack of data, exercised should be caution in patients with severe renal insufficiency.
However, due to lack of data, exercised should be caution in patients with severe renal insufficiency.

Liver
CAUTION
Zolgas 40 Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Zolgas 40 Tablet may be needed. Please consult your doctor.
However, no dose adjustment is required for patients with mild to moderate liver disease.
However, no dose adjustment is required for patients with mild to moderate liver disease.
Frequently asked questions
Usually, Zolgas 40 Tablet is taken once a day, first thing in the morning. If you take Zolgas 40 Tablet twice a day, take 1 dose in the morning and 1 dose in the evening. The tablets should be swallowed whole (remember not be chewed or crushed) and taken at least 1 hour before a meal with some water.
Yes, Zolgas 40 Tablet can be safely taken with domperidone as no harmful effects have been reported clinically. A fixed-dose combination of these two medicines is also available. Domperidone works by increasing the gut motility and Zolgas 40 Tablet decreases the acid production in the stomach. So, this combination is very effective in the treatment of reflux esophagitis associated with acidity, heartburn, intestinal and stomach ulcers.
Yes, you can take antacids along with Zolgas 40 Tablet. Take it 2 hours before or after you take Zolgas 40 Tablet.
Zolgas 40 Tablet is usually prescribed for short term use only. However, if need arises, such as for treating peptic ulcer disease and Zollinger Ellison syndrome (ZES), Zolgas 40 Tablet may be prescribed for a long term duration as well. Long term use may carry an increased risk for side effects and must be discussed with the doctor. Please use Zolgas 40 Tablet as advised by your doctor and under their supervision.
If Zolgas 40 Tablet is used for more than 3 months, certain long term side effects may be seen. The most important of these is low magnesium levels in your blood which may make you feel tired, confused, dizzy, shaky or dizzy. You may also have muscle twitches or irregular heartbeat. If the use is further prolonged for more than a year, you may have an increased risk of bone fractures, stomach infections and vitamin B12 deficiency. Vitamin B12 deficiency can make you anemic, as a result of which you may feel more tired, weak, or pale. Additionally you may have palpitations, shortness of breath, lightheadedness, indigestion, loss of appetite, flatulence (gas) or nerve problems such as numbness, tingling and problem in walking.
If you have been taking Zolgas 40 Tablet for a long time, stopping it abruptly may lead to increased acid production, thereby worsening your symptoms. Therefore, you must discuss any dose changes or if you wish to come off Zolgas 40 Tablet.
Weight gain is reported in less than 1% of the patients taking Zolgas 40 Tablet but the exact cause is unknown. One possible explanation is higher food intake once the reflux symptoms are relieved. Lifestyle modifications such as proper diet and exercise can help to prevent weight gain.
Yes, Zolgas 40 Tablet is relatively safe to use. Most of the people who take Zolgas 40 Tablet do not get a side effect. It is advised to be taken as directed by the doctor for maximum benefit.
Yes, Zolgas 40 Tablet can be taken with ranitidine. According to research reports, there are no significant interactions seen between Zolgas 40 Tablet and ranitidine. However, you must take them together only if prescribed by the doctor.
No, alcohol intake is not advised with Zolgas 40 Tablet. Alcohol itself does not affect the working of Zolgas 40 Tablet, but it can increase the acid production. This may further cause worsening of your symptoms
Fact Box
Chemical Class
Sulfinylbenzimidazole Derivative
Habit Forming
No
Therapeutic Class
GASTRO INTESTINAL
Action Class
Proton-Pump Inhibitors
References
- Wallace JL, Sharkey KA. Pharmacotherapy of Gastric Acidity, Peptic Ulcers, and Gastroesophageal Reflux Disease. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman's: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: The McGraw-Hill Companies, Inc.; 2011. [Accessed 24 Jan. 2019] (online) Available from:
- Esomeprazole. Wilmington, DE: AstraZeneca Pharmaceuticals; 1989 [revised Dec. 2014]. [Accessed 28 Mar. 2019] (online) Available from:
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Esomeprazole. [Updated 2019 Jun 3]. [Accessed 20 Feb. 2020] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 28 Mar. 2019] (online) Available from:
- Esomeprazole [Prescribing Information]. Haridwar, Uttarakhand: Pure & Cure Healthcare Pvt. Ltd.; 2023. [Accessed 22 Jun. 2023] (online) Available from:
- Esomeprazole [Prescribing Information]. Haridwar, Uttarakhand: Pure & Cure Healthcare Pvt. Ltd.; 2023. [Accessed 22 Jun. 2023] (online) Available from:
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Patient concerns
Heartburn Mental disorder Depression Frequent persistent heartburn Gastroesophageal reflux disease Irritable bowel syndrome Indigestion Back flow of acid from stomach Difficulty in swallowing Inflammation of esophagus Excess acid secretion by stomach Intestinal or stomach ulcers
Dr. Sunil Sekhri
Diabetology
You need to be examined in clinic to reach a diagnosis and then appropriate medicine can be prescribed
Moderate Throat Pain in left side Moderate Ear pain. Acid reflux too often
Dr. Vijay Verma
ENT
it may be due to acidity also you may have got some ulcer or infection in that region visit ent specialist near you for proper examination
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Address: plot no.-78/79,2nd floor, sikh rd, jawahar rail colony, secunderabad, telangana 500009
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Country of origin: India
A licensed vendor partner from your nearest location will deliver Zolgas 40 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
A licensed vendor partner from your nearest location will deliver Zolgas 40 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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