Zolpil 5mg Tablet
Written By Dr. Swati Mishra, BDS
Reviewed By Dr. Khushbu Goel, DM, MD
Last updated on 09 Nov 2024 | 01:07 AM (IST)
Zolpil 5mg Tablet is used for short-term treatment of insomnia. It reduces sleep onset time and frequent awakening at night. This medicine improves sleep maintenance and therefore ensures sound sleep.
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General Information
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Product introduction
Zolpil 5mg Tablet should be taken on an empty stomach, preferably just before going to bed. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor as it is habit-forming. Do not stop taking it suddenly without talking to your doctor as it may worsen your symptoms.
Some common side effects of this medicine include memory loss, hallucinations, agitation, headache, vertigo, diarrhea, nausea, vomiting, and back pain. It may also cause fatigue, stomach pain, double vision, and depression. However, these are temporary and resolve on their own after some time. Please consult your doctor if these bother you or do not away.
Zolpil 5mg Tablet also causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you, and do not take alcohol with it as it may worsen the dizziness. Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, hallucinations, or suicidal thoughts while taking this medicine.
Before taking Zolpil 5mg Tablet, inform your doctor about all other medicines that you are taking, so that your doctor can advise if taking this medicine is right for you. Consult your doctor before taking this medicine if you are suffering from any liver or kidney problems. You should avoid smoking and alcohol while using this medicine. Pregnant and breastfeeding mothers should not use this medicine. However, if the need arises, please consult your doctor before using it.
Some common side effects of this medicine include memory loss, hallucinations, agitation, headache, vertigo, diarrhea, nausea, vomiting, and back pain. It may also cause fatigue, stomach pain, double vision, and depression. However, these are temporary and resolve on their own after some time. Please consult your doctor if these bother you or do not away.
Zolpil 5mg Tablet also causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you, and do not take alcohol with it as it may worsen the dizziness. Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, hallucinations, or suicidal thoughts while taking this medicine.
Before taking Zolpil 5mg Tablet, inform your doctor about all other medicines that you are taking, so that your doctor can advise if taking this medicine is right for you. Consult your doctor before taking this medicine if you are suffering from any liver or kidney problems. You should avoid smoking and alcohol while using this medicine. Pregnant and breastfeeding mothers should not use this medicine. However, if the need arises, please consult your doctor before using it.
Uses of Zolpil Tablet
Benefits of Zolpil Tablet
Treatment of Insomnia
Insomnia is a common sleep disorder in which there is difficulty in falling or staying asleep at night. Zolpil 5mg Tablet helps treat insomnia as well as improves sleep quality. Zolpil 5mg Tablet works by slowing activity in the brain to allow sleep. This helps you relax and feel more energetic. It also helps you concentrate better and improves your quality of life.
With Zolpil 5mg Tablet, your sleep problems should improve within 7 to 10 days. Apart from this, it is advisable to make some lifestyle changes to sleep better.
Insomnia is a common sleep disorder in which there is difficulty in falling or staying asleep at night. Zolpil 5mg Tablet helps treat insomnia as well as improves sleep quality. Zolpil 5mg Tablet works by slowing activity in the brain to allow sleep. This helps you relax and feel more energetic. It also helps you concentrate better and improves your quality of life.
With Zolpil 5mg Tablet, your sleep problems should improve within 7 to 10 days. Apart from this, it is advisable to make some lifestyle changes to sleep better.
Side effects of Zolpil Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Zolpil
- Dizziness
- Sleepiness
- Headache
- Nausea
- Stomach pain
- Memory loss
- Vertigo
- Vomiting
- Back pain
- Agitation
- Double vision
- Depression
How to use Zolpil Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zolpil 5mg Tablet is to be taken empty stomach.
How Zolpil Tablet works
Zolpil 5mg Tablet belongs to a group of medicines called non-benzodiazepine hypnotics. It has hypnotic, sedative, and anticonvulsant (manages fits) properties. It works by binding of the GABAA receptor chloride channel macromolecular complex (a chemical messenger) that slows the activity of the nerve cells in the brain and helps fall asleep.
Quick tips
- Your doctor has prescribed Zolpil 5mg Tablet to help you fall asleep faster and sleep for longer.
- It is best taken without food as a high-fat meal can reduce its absorption and effect.
- Take it 30 to 45 minutes before bedtime and only when you have time to sleep for at least 7 hours.
- It makes you feel dizzy next morning. Don't drive or do anything requiring concentration until you know how it affects you.
- It does not affect total sleep time. However, it reduces sleep onset time and frequent awakening at night.
- Never share your medication with any other person who also has a sleep problem.
- Inform your doctor if your sleep doesn’t improve after 7 to 10 days of treatment.
- Stop taking medication and inform your doctor If you experience sleep driving or memory loss.
- Do not stop taking medication suddenly as it may lead to anxiety, mood changes, and restlessness.
Safety advice

Alcohol
UNSAFE
Zolpil 5mg Tablet may cause excessive drowsiness with alcohol.

Pregnancy
CONSULT YOUR DOCTOR
Zolpil 5mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding
SAFE IF PRESCRIBED
Zolpil 5mg Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.

Driving
UNSAFE
Zolpil 5mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney
SAFE IF PRESCRIBED
Zolpil 5mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Zolpil 5mg Tablet is recommended.
However, inform your doctor if you have any kidney disease.
However, inform your doctor if you have any kidney disease.

Liver
CAUTION
Zolpil 5mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Zolpil 5mg Tablet may be needed. Please consult your doctor.
Zolpil 5mg Tablet is generally started at a low dose in patients with mild to moderate liver disease and is not recommended in patients with severe liver disease.
Zolpil 5mg Tablet is generally started at a low dose in patients with mild to moderate liver disease and is not recommended in patients with severe liver disease.

Frequently asked questions
Zolpil 5mg Tablet produces a calming effect on the brain and induces sleep. This calming effect may be perceived as pleasant or feeling high by some individuals. On prolonged use, Zolpil 5mg Tablet may also make an individual dependent such that they are not be able to sleep or function normally without taking it.
Yes, Zolpil 5mg Tablet has abuse potential. However, it is more commonly seen in patients with a history of drug abuse, alcohol consumption, and drug addiction. Therefore, doctors should carefully take history of drug abuse from the patient. Moreover, patients with a history of drug abuse or addiction should be closely monitored during Zolpil 5mg Tablet therapy.
No drug-drug interactions have been found Zolpil 5mg Tablet taken with prednisone. However always consult with your doctor before taking these medicines together.
Zolpil 5mg Tablet is used to treat insomnia, which may help ease anxiety in some patients, although doctors do not prescribe Zolpil 5mg Tablet for anxiety alone because it does not work in the same manner as other sedatives anti-anxiety drugs
The symptoms of Zolpil 5mg Tablet overdose include drowsiness, confusion, problems with coordination, floppy muscles, slow or difficult breathing, and even coma (loss of consciousness for a period of time).
Zolpil 5mg Tablet can make you drowsy during the daytime and also decrease your mental alertness. Therefore, you should not drive or operate heavy machinery until and unless you know how Zolpil 5mg Tablet affects you. Do not drink alcohol while you are taking Zolpil 5mg Tablet. Alcohol can make the side effects of Zolpil 5mg Tablet even worse.
You should not take Zolpil 5mg Tablet if you are allergic to it or any of its ingredients. You should also avoid Zolpil 5mg Tablet if you have a history of depression, mental illness, or suicidal thoughts. A person having a history of drug or alcohol abuse or addiction, having kidney or liver disease, having a lung disease or breathing problems should avoid Zolpil 5mg Tablet. Also, its consumption is not recommended if you are pregnant, planning to become pregnant, or breastfeeding.
No, do not take Zolpil 5mg Tablet with or shortly after a heavy, high-fat meal. Zolpil 5mg Tablet may not work well if it is taken with high-fat foods.
Zolpil 5mg Tablet is used for short-term (2-4 weeks) treatment of insomnia (difficulty falling asleep). It should be taken exactly as prescribed by the doctor. The dose and duration of treatment should not be exceeded else it may lead to dependence (addiction towards medicine).
Yes, dry mouth is a common side effect of Zolpil 5mg Tablet, whereas weight gain is less common with Zolpil 5mg Tablet. If you experience weight gain, it could be due to increased appetite.
Zolpil 5mg Tablet starts working as soon as you take it and may make you very sleepy. You may remain sleepy for some time after you take the medication. Plan to go to bed right after you take Zolpil 5mg Tablet and to stay in bed for 7 to 8 hours. Do not take Zolpil 5mg Tablet if you will be unable to go to bed right away and remain asleep for 7 to 8 hours after taking the medication.
Do not stop taking Zolpil 5mg Tablet without talking to your doctor. If you suddenly stop taking Zolpil 5mg Tablet, you may experience withdrawal symptoms such as unpleasant feelings, stomach and muscle cramps, vomiting, sweating, shakiness, and rarely, seizures.
You can improve your sleep by avoiding caffeine and nicotine, especially late in the day. Avoid exercise during the four hours before bedtime; daily exercise is beneficial to sleep, but can interfere if done close to bedtime. Avoid large meals in the evening. Avoid taking naps. Go to sleep and wake up at the same time each day. Keep the bedroom as dark as possible and maintain a comfortable temperature. Set aside a time to relax before bed and use relaxation techniques.
Insomnia is a common sleep disorder. People with insomnia experience trouble in falling asleep, staying asleep, or both. As a result, they may get too little sleep or have poor-quality sleep, and they may not feel refreshed after waking up.
Insomnia can be of two types- primary or secondary. In primary insomnia, the cause is not known. It can be triggered by life-style changes including long-lasting stress and emotional upset. Whereas, secondary insomnia can be caused due to various reasons such as certain medical conditions (depression, anxiety, post-traumatic stress disorder, Alzheimer's disease, and Parkinson's disease), medicines, sleep disorders, and substances (caffeine and other stimulants, tobacco and other nicotine products, and alcohol).
Fact Box
Chemical Class
Imidazopyridine Derivative
Habit Forming
Yes
Therapeutic Class
NEURO CNS
Action Class
Non-benzodiazepine hypnotics (Z Compounds)
References
- Mihic SJ, Harris RA. Hypnotics and Sedatives. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 467-68.
- Stahl SM, editor. Zolpidem. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 751-54.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1519-20.
- Drugs.com. Zolpidem. [Accessed 19 Mar. 2019] (online) Available from:
- Chaves RG, Lamounier JA, et al. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 19 Mar. 2019] (online) Available from:

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Best medicine for curing insomnia
Dr. Anuneet Sabharwal
Psychiatry
Depends on the cause of insomnia
I can not sleep more than 5 hours,i had thyroid problem,for that thyroid .75 is taking,also taking asomax for b p problem though it is 130/90, my main problem sins is I can't sleep more than 5 hours ,
Dr. Sfurti Mann
Diabetology
Consult a psychiatrist for insomnia
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