Adapalene can cause skin dryness at the site of application. To minimize this dryness, you can apply moisturizer to your skin in the day time. However, make sure that you are using a non-comedogenic moisturizer, which is less likely to clog your pores and increases the severity of your acne.

Your doctor will decide whether you can continue taking or stop taking Adapalene before cosmetic procedures. Please ensure that your doctor knows about all the medicines you are taking before any cosmetic procedure.

Yes, Adapalene is safe to use when used according to your doctor's advice. However, like all medicines, even this medicine has some side effects, but it is not necessary that anyone who is taking these medicines might get all of the side effects. Please talk to your doctor if you get any unpleasant effects while taking this medicine.

It is best to apply Adapalene before bed-time because Adapalene increases the skin's sensitivity to sunlight and can cause skin irritation when exposed to sunlight. Therefore, applying this medicine in the day time requires the user to take several precautions to avoid direct exposure to sunlight. Hence, it is best to apply this medicine before bed-time.