Famotidine may be taken with or without food. It can be taken once daily before bedtime or twice daily in the morning and before bedtime, as recommended.

Famotidine starts working as fast as within 15 minutes from when it is given. Its effect is seen to last all day or all night.

Famotidine and Omeprazole belong to different groups of medicines. While Famotidine belongs to histamine H2 antagonists group, Omeprazole belongs to proton pump inhibitors group. Both these medicines work by reducing the amount of acid made by the stomach, to relieve the symptoms and allow healing.

Famotidine may have some serious side effects, but these are rare. These side effects may include hives, skin rash, itching, hoarseness and difficulty in breathing or swallowing. Another serious symptom may be swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs. Inform your doctor in case you notice any of the mentioned symptoms.

Avoid taking aspirin and other painkillers used to treat arthritis, period pain or headache. These medicines may irritate the stomach and make your condition worse. Contact your doctor who may suggest other medicines. Avoid coffee, tea, cocoa and cola drinks because these contain ingredients that may irritate your stomach. Eat smaller, more frequent meals. Eat slowly and chew your food carefully. Try not to rush at meal times. You should stop or cut down on smoking.

There is limited data available on whether Famotidine can be used for a long term or not, but it is a relatively safe medicine. You should take it for the duration advised by your doctor. Do not take over-the-counter Famotidine for longer than 2 weeks unless advised by your doctor.