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Flupirtine
INFORMATION ABOUT FLUPIRTINE
Flupirtine Uses
Flupirtine is used in treatment of pain relief.
How Flupirtine works
Flupirtine decreases the perception of pain by blocking the transmission of pain signals to the brain.
Common side effects of Flupirtine
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common
Fatigue, Dizziness, Nausea, Dryness in mouth, Tremors, Heartburn, Vomiting, Abdominal pain, Constipation, Loss of appetite, Depression, Headache, Abdominal discomfort, Sleep disturbance, Increased sweating, Restlessness, Nervousness, Flatulence, Diarrhea
CONTENT DETAILS
Last updated
23 Dec 2022 | 05:59 AM (UTC)
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Expert advice for Flupirtine
  • Flupirtine is given when pain killers (NSAIDs) cannot be given due to gastric damage caused by them.
  • Inform your doctor before starting Flupirtine if
    • You have an underlying liver disease
    • You take alcohol regularly
    • You are pregnant or planning to get pregnant or breastfeeding
  • Get your liver function tests done before starting Flupirtine and follow up tests every week while you are taking the medicine.
  • Stop taking Flupirtine and immediately inform your doctor if you get any symptoms of liver disease like nausea, vomiting, stomach pain or yellow colored urine.
Frequently asked questions for Flupirtine
Yes, Flupirtine is seen to be beneficial in the treatment of fibromyalgia in some clinical studies, however, Flupirtine is yet to get formal regulatory approval for this condition. Fibromyalgia is a disease that is characterized by musculoskeletal pain, fatigue, and depression.
Both Flupirtine and paracetamol help in relieving pain but they work in entirely different ways. When paracetamol is given with Flupirtine, pain relief is better as compared to single drug use. However, both can cause liver toxicity, so monitoring of liver function is very important when taken together.
Yes, Flupirtine causes liver toxicity. Use of Flupirtine is contraindicated in patients with an underlying liver disease.
Flupirtine can be used for the relief of pain associated with osteorthritis and post orthopedic surgery pain. It is especially useful for patients who cannot take NSAIDs because of the risk of NSAID-induced gastritis.
There have been case reports that Flupirtine causes green discoloration of urine. However, this is not a very commonly seen effect. Inform your doctor if you experience this symptom.
Flupirtine is not approved for the treatment of epilepsy. However, a few animal studies have shown a beneficial effect of Flupirtine for treating epilepsy and this effect is still being explored.
Yes, you can experience withdrawal symptoms once you stop using Flupirtine like sweating, tremor, and mood alterations with long term use of Flupirtine. Inform your doctor if you have these symptoms.