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Human Rabies Immunoglobulin

Written By Dr. Sakshi SharmaReviewed By Dr. Ashish Ranjan
Last updated 13 Jun 2023 | 11:29 AM (UTC)

Human Rabies Immunoglobulin Uses

Human Rabies Immunoglobulin is used for prevention of Rabies.

How Human Rabies Immunoglobulin works

Human Rabies Immunoglobulin is generally given with vaccines. Human Rabies Immunoglobulin contains chemicals that protect the patient against infections.

Common side effects of Human Rabies Immunoglobulin

Injection site pain, Headache, Muscle pain, Joint pain, Dizziness, Fatigue, Fever, Pain in extremity, Vomiting, Bruising
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Expert advice for Human Rabies Immunoglobulin

  • Protects you against rabies after you have been bitten, scratched or received any injury from a suspected animal with rabies.
  • Given with first dose of rabies vaccine, or not more than 7 days after the scratch or injury.
  • Given by injection around the wound and into the muscle at the side of the thigh (intramuscular).

Frequently asked questions for Human Rabies Immunoglobulin

Human Rabies Immunoglobulin is a solution containing a large amount of rabies antibodies. It is used to provide protection against rabies. It is given either along with the first dose of anti-rabies vaccine(ARV) or not more than 7 days later.
Rabies is a 100% preventable disease. Proper wound management and simultaneous administration of Human Rabies Immunoglobulin combined with anti-rabies vaccine (ARV) is almost invariably effective in preventing rabies, even after high-risk exposure.
Human Rabies Immunoglobulin is not required for patients who have previously received a complete vaccination series of rabies.
Whether Human Rabies Immunoglobulin is painful or not depends on your pain tolerance. During your initial treatment, a healthcare professional will put Human Rabies Immunoglobulin in the area where you were bitten. This can be painful. Therefore, a relatively greater amount of Human Rabies Immunoglobulin may be required to be placed in and around the wound site to ease out your pain and treat infection.
Equine Rabies Immunoglobulin is more economical as compared to Human Rabies Immunoglobulin i.e., human rabies immunoglobulin (HRIG). Hence, it is more affordable to patients in developing countries, like India. However, Equine Rabies Immunoglobulin has a high potential to cause anaphylaxis (a severe, potentially life-threatening allergic reaction), serum sickness and other allergic reactions and thus physicians are hesitant to use it.