Imipenem + Cilastatin

Last updated 07 Apr 2021 | 05:27 AM (UTC)

Imipenem + Cilastatin Uses

Imipenem+Cilastatin is used in the treatment of severe bacterial infections.

How Imipenem + Cilastatin works

Imipenem + Cilastatin is a combination of two medicines: Imipenem and Cilastatin. Imipenem is an antibiotic. It works by preventing the formation of the bacterial protective covering which is essential for the survival of bacteria in the human body. Cilastatin is dehydropeptidase I inhibitor which blocks the activity of an enzyme (dehydropeptidase I) that causes breakdown of Imipenem . Hence, it helps Imipenem stay active in your body for a longer period of time.

Common side effects of Imipenem + Cilastatin

Nausea, Vomiting, Diarrhea, Rash, Thrombophlebitis, Increased liver enzymes

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Medicine brands for Imipenem + Cilastatin

Zienam

MSD Pharmaceuticals Pvt Ltd

Glenmark Pharmaceuticals Ltd

₹1883 to ₹3832

4 variant(s)

Zilamac

Macleods Pharmaceuticals Pvt Ltd

United Biotech Pvt Ltd

Alkem Laboratories Ltd

₹796 to ₹2640

3 variant(s)

Maxigard

Emcure Pharmaceuticals Ltd

₹1141 to ₹3087

2 variant(s)

Expert advice for Imipenem + Cilastatin

Imipenem + Cilastatin is used to treat severe bacterial infections, including those acquired in hospital and those involving many different types of bacteria.
It is given by a drip into a vein (intravenous infusion) over 20 to 60 minutes.
Tell you doctor if you are allergic to penicillin as this medicine should be avoided or used with caution in penicillin allergy.
Your doctor may monitor your liver and kidney function while you are having treatment with this medication.
Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your stools.
Inform your doctor if you are pregnant, planning to conceive, or breastfeeding.

Frequently asked questions for Imipenem + Cilastatin

Q. For how long is Imipenem+Cilastatin used?

Duration of treatment with Imipenem+Cilastatin depends on the severity of your infection, which will be decided by your doctor.

Q. How long does Imipenem+Cilastatin take to work?

Usually, Imipenem+Cilastatin starts working soon after taking it. However, it may take some days to kill all the harmful bacteria and make you feel better.