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Pralidoxime

Written By Dr. Shreya GuptaReviewed By Dr. Lalit Kanodia
Last updated 13 Jun 2023 | 11:25 AM (UTC)

Pralidoxime Uses

Pralidoxime is used in the treatment of organophosphate poisoning.

How Pralidoxime works

Pralidoxime reactivates the enzymes blocked by many pesticides (organophosphates). It is an antidote used in the poisoning of these pesticides.
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Expert advice for Pralidoxime

  • Pralidoxime is given as an injection into veins, muscles or under the skin by a doctor only.
  • Your doctor will monitor you closely for a period of 72 hours after giving the medicine.
  • Your doctor will closely monitor your heart rate, blood pressure, breathing rate and oxygen level during the treatment.
  • It may cause temporary blurring of your vision. Do not drive or do anything that requires concentration until you know how it affects you.

Frequently asked questions for Pralidoxime

Pralidoxime works by reactivating the enzyme acetylcholinesterase, which has been inactivated by pesticides or certain drugs, and breaks down the excess acetylcholine resulting from poisoning. Thus, it helps in reversing muscle weakness or respiratory depression caused by poisoning or drug over dosing.