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Topotecan

Written By Dr. Anuj SainiReviewed By Dr. Lalit Kanodia
Last updated 22 Feb 2021 | 12:52 PM (UTC)

Topotecan Uses

Topotecan is used in the treatment of ovarian cancer.

How Topotecan works

Topotecan is an anti-cancer medication. It works by suppressing the activity of an enzyme (topoisomerase I) involved in DNA multiplication of the cancer cells. This slows the growth of cancer cells and eventually kills them.
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Expert advice for Topotecan

  • Topotecan helps treat ovarian cancer.
  • It is given by a drip into a vein (intravenous infusion).
  • Do not drive or operate machinery as Topotecan may cause tiredness, drowsiness or weakness.
  • Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine.
  • Your doctor may get regular blood tests done to monitor your blood cells during treatment with this medicine.
  • Inform your doctor immediately if you notice any signs of infection such as fever, sore throat, rash or severe diarrhea.

Frequently asked questions for Topotecan

Generally Topotecan treatment is for 4 cycles of 21 day each, patient is given Topotecan for first 5 days of each cycle.
Yes, Topotecan may cause temporary hair loss.
Yes, Topotecan may cause flare reaction.
Topotecan may start its action once the infusion is started, however, the complete effect may be assessed only after completion of 4 cycles.
Topotecan is a vesicant (irritant).
Yes Topotecan is effective if used at prescribed doses for the prescribed duration as advised by your doctor.
It is a treatment therapy that includes Topotecan with or without combination of other drugs in treatment of cancer (Usually ovarian or lung cancer).
Topotecan is either administered orally as a capsule or as an intravenous Infusion in the arm over a period of 30 min.