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BCR-ABL Qualitative PCR

For men & women

Earliest reports in

108 hours

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The BCR-ABL Gene Translocation (Qualitative) test can help doctors to diagnose chronic myelogenous leukaemia (CML) and a type of B-cell acute lymphoblastic leukaemia (ALL) and monitor their treatment. Of the 23 pairs of chromosomes in your body, the BCR gene is usually on chromosome 22 and the ABL on chromosome 9. When portions of BCR and ABL genes break off and switch places, the resulting fused gene is the BCR-ABL gene.

Usually, it is a blood test, or doctors may opt for a bone marrow biopsy and aspiration, where they insert a needle via your hip bone to take a bone marrow sample. Doctors use anaesthesia for the procedure. If your reports confirm the presence of this gene, you may have ALL or CML. Consult a specialist for proper treatment.

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What does BCR-ABL Qualitative PCR measure?

BCR-ABLtesting is ordered if it is suspected that a person has CML or Philadelphia chromosome (Ph)-positive ALL. Initial testing may be indicated when a person has symptoms such as:
-Fatigue
-Weight loss
-Joint or bone pain
-Enlarged spleen
-Night sweats
-Fever
-Abnormal findings on a complete blood count (CBC)

Content created by

Dr. Swati Gupta (Anand)

MBBS, MD Lab Medicine

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Last Updated

17th Mar 2026