Serum Homocysteine

Homocysteine is an amino acid produced in the body during the metabolism of methionine, an essential amino acid obtained from the diet. The Serum Homocysteine test assesses the levels of homocysteine and helps in determining cardiovascular risk, evaluating neurological disorders such as Alzheimer's disease and dementia, and predicting pregnancy complications such as preeclampsia, recurrent miscarriages, and neural tube defects in the fetus. 

The Serum Homocysteine test also helps detect vitamin B6, B12, and folate deficiencies. Since these three vitamins are essential for homocysteine's metabolism (breaking down), increased amino acid levels may indicate a deficiency of these vitamins. Additionally, this test helps diagnose homocystinuria, a rare condition that prevents protein breakdown in newborns and infants.

The Serum Homocysteine test may be recommended for individuals with a family history of cardiovascular disease, those with risk factors for heart disease, and those with a history of stroke or peripheral artery disease. It is also beneficial in individuals with certain medical conditions, such as chronic kidney disease and hypothyroidism, or those with a history of poor dietary intake of vitamins B6, B12, or folate.

No fasting is required for this test. You may eat and drink normally as per your daily routine. Test result ranges are approximate and may differ slightly between labs depending on the methodology and laboratory guidelines. Talk to your doctor about your specific test results. If you have high homocysteine levels, your doctor may suggest dietary changes. If you are considering taking vitamin supplements, talk to your doctor first.