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Acronil-OD 400 Tablet ER
Flupirtine (400mg)
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Acronil-OD 400 Tablet ER is a pain relieving medicine. It is used to treat acute and chronic pain associated with various conditions such as muscle pain, headache, nerve pain, postoperative pain, and menstrual cramps. It is not recommended for use in patients less than 18 years of age.
Written By Dr. Sakshi Sharma, BDS,
Reviewed By Dr. Ashish Ranjan, MD (Pharmacology), MBBS,
Last updated on 12 Nov 2024 | 01:08 AM (IST)
Written By Dr. Sakshi Sharma, BDS,
Reviewed By Dr. Ashish Ranjan, MD (Pharmacology), MBBS,
Last updated on 12 Nov 2024 | 01:08 AM (IST)
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10 tablet er
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General Information
The content is shown in English



Product introduction
Acronil-OD 400 Tablet ER can be taken with or without food. In general, you should try to use the smallest amount necessary to control your symptoms, for the shortest possible time. You should take this medicine regularly while you need it. Try not to miss doses as this will make the medicine less effective.
Some of the common side effects of this medicine include fatigue, dizziness, drowsiness, nausea, dryness in mouth, and abdominal bloating. If any of these side effects do not go away or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms.
To make sure it is safe for you, before taking this medicine, let your doctor know if you have any medical conditions or disorders. You should also tell your doctor all the other medicines you are using or taking. Pregnant and breastfeeding women should consult their doctors before using this medicine.
Some of the common side effects of this medicine include fatigue, dizziness, drowsiness, nausea, dryness in mouth, and abdominal bloating. If any of these side effects do not go away or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms.
To make sure it is safe for you, before taking this medicine, let your doctor know if you have any medical conditions or disorders. You should also tell your doctor all the other medicines you are using or taking. Pregnant and breastfeeding women should consult their doctors before using this medicine.
Uses of Acronil Tablet ER
Benefits of Acronil Tablet ER
Pain relief
Acronil-OD 400 Tablet ER helps relieve moderate to severe pain in conditions that affect joints and muscles. It works by blocking chemical messengers in the brain that tell us we have pain. It can help relieve pain in conditions like muscle pain, headache, nerve pain, postoperative pain, and menstrual cramps. The dose and duration will be decided by the doctor depending on the condition you are being treated for. This medicine helps one go about their daily activities more easily and have a better, more active, quality of life.
Acronil-OD 400 Tablet ER helps relieve moderate to severe pain in conditions that affect joints and muscles. It works by blocking chemical messengers in the brain that tell us we have pain. It can help relieve pain in conditions like muscle pain, headache, nerve pain, postoperative pain, and menstrual cramps. The dose and duration will be decided by the doctor depending on the condition you are being treated for. This medicine helps one go about their daily activities more easily and have a better, more active, quality of life.
Side effects of Acronil Tablet ER
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Acronil
- Fatigue
- Dizziness
- Nausea
- Dryness in mouth
- Tremors
- Heartburn
- Vomiting
- Abdominal pain
- Constipation
- Loss of appetite
- Depression
- Headache
- Abdominal discomfort
- Sleep disturbance
- Increased sweating
- Restlessness
- Nervousness
- Flatulence
- Diarrhea
How to use Acronil Tablet ER
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Acronil-OD 400 Tablet ER may be taken with or without food, but it is better to take it at a fixed time.
How Acronil Tablet ER works
Acronil-OD 400 Tablet ER decreases the perception of pain by blocking the transmission of pain signals to the brain.
Quick tips
- Acronil-OD 400 Tablet ERÂ is given when pain killers (NSAIDs) cannot be given due to gastric damage caused by them.
- Inform your doctor before starting Acronil-OD 400 Tablet ER if
- You have an underlying liver disease
- You take alcohol regularly
- You are pregnant or planning to get pregnant or breastfeeding
- Get your liver function tests done before starting Acronil-OD 400 Tablet ER and follow up tests every week while you are taking the medicine.
- Stop taking Acronil-OD 400 Tablet ER and immediately inform your doctor if you get any symptoms of liver disease like nausea, vomiting, stomach pain or yellow colored urine.
Safety advice

Alcohol
UNSAFE
Acronil-OD 400 Tablet ER may cause excessive drowsiness with alcohol.

Pregnancy
CONSULT YOUR DOCTOR
Acronil-OD 400 Tablet ER may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Acronil-OD 400 Tablet ER during breastfeeding is not available. Please consult your doctor.

Driving
CONSULT YOUR DOCTOR
It is not known whether Acronil-OD 400 Tablet ER alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Kidney
CAUTION
Acronil-OD 400 Tablet ER should be used with caution in patients with kidney disease. Dose adjustment of Acronil-OD 400 Tablet ER may be needed. Please consult your doctor.

Liver
CAUTION
Acronil-OD 400 Tablet ER should be used with caution in patients with liver disease. Dose adjustment of Acronil-OD 400 Tablet ER may be needed. Please consult your doctor.
Frequently asked questions
Yes, Acronil-OD 400 Tablet ER is seen to be beneficial in the treatment of fibromyalgia in some clinical studies, however, Acronil-OD 400 Tablet ER is yet to get formal regulatory approval for this condition. Fibromyalgia is a disease that is characterized by musculoskeletal pain, fatigue, and depression.
Both Acronil-OD 400 Tablet ER and paracetamol help in relieving pain but they work in entirely different ways. When paracetamol is given with Acronil-OD 400 Tablet ER, pain relief is better as compared to single drug use. However, both can cause liver toxicity, so monitoring of liver function is very important when taken together.
Yes, Acronil-OD 400 Tablet ER causes liver toxicity. Use of Acronil-OD 400 Tablet ER is contraindicated in patients with an underlying liver disease.
Acronil-OD 400 Tablet ER can be used for the relief of pain associated with osteorthritis and post orthopedic surgery pain. It is especially useful for patients who cannot take NSAIDs because of the risk of NSAID-induced gastritis.
There have been case reports that Acronil-OD 400 Tablet ER causes green discoloration of urine. However, this is not a very commonly seen effect. Inform your doctor if you experience this symptom.
Acronil-OD 400 Tablet ER is not approved for the treatment of epilepsy. However, a few animal studies have shown a beneficial effect of Acronil-OD 400 Tablet ER for treating epilepsy and this effect is still being explored.
Yes, you can experience withdrawal symptoms once you stop using Acronil-OD 400 Tablet ER like sweating, tremor, and mood alterations with long term use of Acronil-OD 400 Tablet ER. Inform your doctor if you have these symptoms.
Fact Box
Chemical Class
Pyridine Derivative
Habit Forming
No
Therapeutic Class
PAIN ANALGESICS
Action Class
Selective neuronal potassium channel openers (SNEPCO)
References
- Sciencedirect. Flupirtine. [Accessed 02 Apr. 2019] (online) Available from:
- Harish S, Bhuvana K, Bengalorkar GM, et al. Flupirtine: Clinical pharmacology. J Anaesthesiol Clin Pharmacol. 2012;28(2):172-7. [Accessed 24 Jan. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 02 Apr. 2019] (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: Consern Pharma Limited
Address: Consern Pharma Private Limited, Kuljive Mahajan(Mg. Director), Rural Focal Point, V.P.O. Tibba, Ludhiana - 141120, Punjab, India
Address: Consern Pharma Private Limited, Kuljive Mahajan(Mg. Director), Rural Focal Point, V.P.O. Tibba, Ludhiana - 141120, Punjab, India
Vendor Details
Country of origin: India
A licensed vendor partner from your nearest location will deliver Acronil-OD 400 Tablet ER. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
A licensed vendor partner from your nearest location will deliver Acronil-OD 400 Tablet ER. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- Glucose - Postprandial
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid-19 Test (RT-PCR technique)
- LFT (Liver Function Test)
- Kidney Function Test
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid
- Vitamin B12
- C- Reactive Protein Quantitative
- Urine Culture and Sensitivity
- Serum Electrolyte
- Serum Calcium
- Creatinine
- Diabetes Screening
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hemoglobin
- Complete Haemogram
Why we need a prescription?
Provide right medicines
Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose
In accordance with the law
Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945












