Arbitus Tablet

Reviewed By Dr. Varun Gupta, MD Pharmacology, MBBS

Last updated on 11 Nov 2024 | 01:07 AM (IST)

Arbitus Tablet is used in the treatment of cancer of the prostate gland. It may be also used to treat other conditions, as determined by the doctor. It is sometimes used with certain other medicines as part of combination chemotherapy.

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₹38315 MRP ₹395003% off

General Information

Contains

Abiraterone Acetate (250mg)

Marketer

Dr Reddy's Laboratories Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Arbitus Tablet should not be taken on an empty stomach. Taking it with food may cause side effects. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include vomiting, decreased potassium level in blood, edema (swelling), decreased white blood cell count, and fatigue. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. Other than this, yellowing of skin, loss of appetite, shortness of breath, dark urine and nausea can happen, which indicate some liver problem. Your doctor might check you for liver function, blood pressure, and the level of potassium in your blood.

Before taking it, tell your doctor if have high blood pressure, heart problem, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. It may harm your baby. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. You may be asked for regular monitoring of blood glucose level while on treatment.

Uses of Arbitus Tablet

Prostate cancer

Benefits of Arbitus Tablet

Prostate cancer
Prostate gland is a small walnut-sized gland that produces a fluid called seminal fluid that nourishes and transports sperms in males. The most common symptom of prostate cancer is difficulty with urination, but sometimes there are no symptoms at all. Arbitus Tablet decreases or stops the growth of cancer cells by decreasing the amount of testosterone (natural hormone in males) in men. This also relieves difficulty in passing urine and makes it easier for you to urinate.

Side effects of Arbitus Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Arbitus

Edema (swelling)
Vomiting
Decreased potassium level in blood
Fatigue
Anemia (low number of red blood cells)
Urinary tract infection
Diarrhea
High blood pressure
Cough
Joint swelling

How to use Arbitus Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Arbitus Tablet is to be taken empty stomach.

How Arbitus Tablet works

Arbitus Tablet is an anticancer medication. It works by preventing androgen (male hormone) production in man. This is done by inhibiting an enzyme (CYP17) that is responsible for the production of androgen. This is how it slows down the growth of prostate cancer.

All substitutes for Arbitus Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Arbitus Tablet treats prostate cancer that has spread to other parts of the body.
It is usually taken with another medicine called prednisolone to reduce unwanted side effects.
It must be taken on an empty stomach. Don't eat any food for at least 2 hours before or 1 hour after your dose.
Always use effective birth control measures to prevent pregnancy while taking this medicine.
Your doctor may regularly monitor your liver function, blood pressure, and the level of potassium in your blood while you are having treatment with this medicine.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Arbitus Tablet. Please consult your doctor.

Pregnancy

UNSAFE

Arbitus Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.

Breast feeding

UNSAFE

Arbitus Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

SAFE

Arbitus Tablet does not usually affect your ability to drive.

Kidney

CAUTION

Arbitus Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Arbitus Tablet may be needed. Please consult your doctor.

Liver

CAUTION

Arbitus Tablet should be used with caution in patients with liver disease. Dose adjustment of Arbitus Tablet may be needed. Please consult your doctor.

Frequently asked questions

Can Arbitus Tablet cure prostate cancer?

Arbitus Tablet does not cure cancer but helps in prolonging and improving the life of the patient. Moreover, when prostate cancer is treated with Arbitus Tablet then the frequency of fractures is relatively less. Similarly, the increase in pain is less common with Arbitus Tablet.

Is Arbitus Tablet a chemotherapy drug?

Arbitus Tablet is a hormonal treatment not a chemotherapy drug. It is used to treat prostate cancer in adult men that has spread to other parts of the body. Arbitus Tablet stops your body from making testosterone. This can slow down the growth of prostate cancer.

Why do I need to take prednisolone with Arbitus Tablet?

Your doctor will always prescribe prednisolone with Arbitus Tablet. Taking these two medicines together lowers the risk of getting high blood pressure, fluid retention (having too much water in your body), or having reduced levels of potassium in your blood, which can occur due to Arbitus Tablet.

Does Arbitus Tablet affect liver?

Arbitus Tablet can cause severe liver problems. In very rare cases, Arbitus Tablet may even cause failure of the liver to function (called acute liver failure), which can even lead to death. Tell your doctor if you experience yellowing of the skin or eyes, darkening of the urine, or severe nausea or vomiting, as these could be signs or symptoms of liver problems.

How frequently should the liver investigations be done?

Liver enzymes should be measured prior to starting the treatment, every two weeks for the first three months into the treatment, and monthly thereafter. If you develop clinical symptoms or signs suggestive of liver toxicity, liver enzymes should be measured immediately. If the liver enzyme levels are increased beyond certain levels, your doctor may temporarily discontinue the treatment with Arbitus Tablet.

How to take Arbitus Tablet?

Arbitus Tablet should be taken on an empty stomach with water 1 hour before eating or at least 2 hours after eating. Taking it with food may cause increased and variable levels of Arbitus Tablet in your blood which can be harmful. Remember not to crush or chew the tablet.

Fact Box

Chemical Class

Androstene Derivative

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Anticancer-others

Related lab tests

Prostate Specific Antigen (Free) PSA

Prostate Specific Antigen (Total) PSA

References

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 4-5.
Abiraterone acetate. High Wycombe, Buckinghamshire: Janssen-Cilag Ltd.; 2017. [Accessed 26 Mar. 2019] (online) Available from:
Abiraterone Acetate. Patheon Inc.: Mississauga, Canada; 2011 [revised May 2016]. [Accessed 26 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:
Abiraterone acetate [Prescribing Information]. Toronto, Canada: Patheon Inc.; 2011. [Accessed 20 Feb. 2024] (online) Available from:
CiplaMed. Abiraterone Acetate [Prescribing Information]. [Accessed 25 Jul. 2024] (online) Available from:

User feedback

What are you using Arbitus Tablet for?

Prostate cancer

100%

Patient concerns

I have problem of frequent urination at night. My father had same at his time.Doctor told me that I am having BPH.Also I went through PSA whose result is 1.8 increased prostate gland size is 40 which came in ultrasound report .When doctor did some test by inserting his finger in my rectal area I felt abnormal pain.doctor asked me to go for a culture test so as to check which can be the best medicine for BPH for me. Kindly suggest if it can be something else like prostate cancer.

Dr. Vijay Sharnangat

Medical Oncology and Hematology

May not be prostate cancer, it is only begnin enlargement of prostate.

Do i have prostrate cancer. Married but now having difficulty in having relation with wife. Penis not hard in the morning. Having problem with self spontaneous erection. Please help. God Bless.

Dr. Sanjay Singh Rai

Medical Oncology and Hematology

Not a symptom of prostate cancer

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Dr Reddy's Laboratories Ltd
Address: Dr. Reddy's Laboratories Ltd., Village Malpur, P.O.Bhud, Baddi, Dist. Solan, H.P.

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Arbitus Tablet

General Information

Contains

Marketer

Storage

Product introduction

Uses of Arbitus Tablet

Benefits of Arbitus Tablet

Side effects of Arbitus Tablet

How to use Arbitus Tablet

How Arbitus Tablet works

All substitutes for Arbitus Tablet

Xbira 250mg Tablet

Samtica 250mg Tablet

Abiratas 250mg Tablet

Abura 250mg Tablet

Arabira 250 Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

Can Arbitus Tablet cure prostate cancer?

Is Arbitus Tablet a chemotherapy drug?

Why do I need to take prednisolone with Arbitus Tablet?

Does Arbitus Tablet affect liver?

How frequently should the liver investigations be done?

How to take Arbitus Tablet?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Prostate Specific Antigen (Free) PSA

Prostate Specific Antigen (Total) PSA

References

User feedback

What are you using Arbitus Tablet for?

Patient concerns

Do i have prostrate cancer. Married but now having difficulty in having relation with wife. Penis not hard in the morning. Having problem with self spontaneous erection. Please help. God Bless.

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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