Biophenox 50mg Injection

Written By Dr. Betina Chandolia, MDS, BDS

Reviewed By Dr. Ashish Ranjan, MD (Pharmacology), MBBS

Last updated on 10 Nov 2024 | 01:10 AM (IST)

Biophenox 50mg Injection is a medicine used to treat high blood pressure associated with tumor of the adrenal glands called Pheochromocytoma. Lowering blood pressure helps to prevent future heart attack and stroke.

Genuine

Authenticity Assured

Prescription

required

₹1654 MRP ₹17053% off

General Information

Contains

Phenoxybenzamine (50mg)

Marketer

United Biotech Pvt Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Biophenox 50mg Injection is given by or under the supervision of a doctor. You should take it in the dose and duration as advised by the doctor. It is important to take it even if you feel well or if your blood pressure is controlled. Most people with high blood pressure do not feel ill, but if you stop taking this medicine, your condition could get worse. Your doctor will decide the time period till which you need to take this medicine.

Making some changes in your lifestyle will also help to lower your blood pressure. These may include regular exercise, losing weight, smoking cessation, reducing alcohol intake, and reducing the amount of salt in your diet as advised by your doctor. This medicine is tolerated well by most patients but it has few side effects also. Some patients may experience dizziness and sudden lowering of blood pressure on standing. Other side effects include nausea, vomiting, ejaculation disorder, and increased heart rate. Let your doctor know if these side effects bother you or do not go away.

Before taking this medicine, let your doctor know if you have any heart or kidney disease. Pregnant or breastfeeding mothers should also consult their doctor before taking it. Your doctor may check your kidney function, heart rate and blood pressure at regular intervals while you are taking this medicine.

Uses of Biophenox Injection

Hypertension (high blood pressure)

Benefits of Biophenox Injection

Hypertension (high blood pressure)
If your blood pressure is controlled you are less at risk of having a heart attack or stroke. Biophenox 50mg Injection reduces the chances of heart diseases and helps you remain healthier for longer. Take it regularly and make appropriate lifestyle changes, such as eating healthy and staying active, to maximize the effectiveness of this medicine.

How to use Biophenox Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Biophenox Injection works

Biophenox 50mg Injection is an alpha blocker which helps reduce blood pressure in pheochromocytoma (a tumour of the adrenal gland). It works by opposing the action of certain hormones released from the tumor that cause the blood vessels to narrow and raise blood pressure.

Quick tips

Biophenox 50mg Injection is given as a drip into a vein (intravenous infusion) under the supervision of a doctor.
Take it in addition to lifestyle modification with regular exercise, a balanced diet, and smoking cessation.
To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
It may cause dizziness or sleepiness. Do not drive or do anything that requires concentration until you know how it affects you.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Safety advice

Alcohol

UNSAFE

Biophenox 50mg Injection may cause excessive drowsiness with alcohol.

Pregnancy

CONSULT YOUR DOCTOR

Biophenox 50mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Biophenox 50mg Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Biophenox 50mg Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Biophenox 50mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Biophenox 50mg Injection may be needed. Please consult your doctor.
Use of Biophenox 50mg Injection is not recommended in patients with serious kidney disease.

Liver

CONSULT YOUR DOCTOR

There is limited information available on the use of Biophenox 50mg Injection in patients with liver disease. Please consult your doctor.

Frequently asked questions

How long should Biophenox 50mg Injection be taken?

You should take it as long as your doctor has recommended it to you. Do not stop taking it without talking to you doctor first. Long-term use of Biophenox 50mg Injection is not recommended as cases of developing cancer have been reported. Consult your doctor before starting the treatment.

Who should not use Biophenox 50mg Injection?

Biophenox 50mg Injection should not be given to patients who are allergic to it. Additionally, in patients with a recent history (within the last month) of stroke or heart attack, Biophenox 50mg Injection should be avoided. Tell your doctor if any of these conditions apply to you.

How does Biophenox 50mg Injection cause tachycardia?

Biophenox 50mg Injection belongs to alpha receptor blockers class of medicines. Alpha receptors blockade decreases resistance thereby increasing blood flow to the skin, mucosa (membrane that lines various cavities of the body), and abdominal viscera (membrane lining the abdomen). This results in lowering of blood pressure. This reduced blood pressure and increased release of chemical messenger (noradrenaline) results in reflex tachycardia.

Why is Biophenox 50mg Injection used for pheochromocytoma?

Biophenox 50mg Injection helps in reducing the increased blood pressure caused by Pheochromocytoma. It is a tumor of the adrenal glands. It causes the release of certain substances (catecholamines) from the adrenal glands into the bloodstream in large quantities, causing high blood pressure. Biophenox 50mg Injection works by blocking alpha receptors, thereby decreasing blood pressure.

What are the advantages of using Biophenox 50mg Injection in pheochromocytoma?

Using Biophenox 50mg Injection in pheochromocytoma is beneficial due to its long duration of action leading to twice daily dosing. Along with that, it prevents episodic increase of catecholamine releases during pre- and post-operative period which helps in keeping the blood pressure under control during surgical procedures.

What are other uses of Biophenox 50mg Injection?

Biophenox 50mg Injection is sometimes effective in treating Raynaud’s phenomenon. This condition results in discoloration of the fingers and/or toes after exposure to changes in temperature (cold or hot) or emotional events. Biophenox 50mg Injection is also useful in treating frostbite.

Can Biophenox 50mg Injection affect sex life?

Yes, use of Biophenox 50mg Injection may affect sex life. It may cause inhibition of ejaculation and may make the patient impotent. However, these effects are generally mild and lasts for only a short time. Discuss with your doctor if you experience this.

What are the symptoms of overdose of Biophenox 50mg Injection?

Taking more than the recommended dose of Biophenox 50mg Injection may cause significant decrease in blood pressure which may last for several hours, increased heartbeat, and one may even collapse. If you accidentally take an overdose of this medicine, contact your doctor and seek immediate medical help.

How quickly does Biophenox 50mg Injection work?

The maximum effect of Biophenox 50mg Injection is attained in about 1 hour after the dose. However, it may take several hours to see the effect after a single oral dose. These effects may persist for 3-4 days.

Fact Box

Chemical Class

Phenylmethylamines

Habit Forming

Therapeutic Class

CARDIAC

Action Class

Adrenergic receptor antagonist - non selective

Related lab tests

Kidney Function Test

References

Westfall TC, WestfallIn DP. Adrenergic Agonists and Antagonists. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 309-10.
Robertson D, Biaggioni I. Adrenoceptor Antagonist Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 152.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1106-107.

Patient concerns

I am a patient of hypertension

Dr. Jyoti Kapoor Madan

Psychiatry

Hypertension is clinal condition of high blood pressure. Please see a physician.

Some times I had lot of hypertension

Dr. Jyoti Kapoor Madan

Psychiatry

Hypertension is clinically high blood pressure. Persistent high arterial blood pressure above 120/80 mm HG is termed as pre-hypertension or hypertension, but the point to be emphasized is that this rise in blood pressure is persistent. Transient increase in BP occurs in stress and anxiety and needs to be treated accordingly.

Want to know more

We provide you with authentic, trustworthy and relevant information

Have issue with the content

Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: United Biotech Pvt Ltd
Address: FC/B-1 (Extn.), Mohan Co-operative Industrial Estate Mathura Road, New Delhi - 110 044

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Provide right medicines

Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose

In accordance with the law

Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945

Biophenox 50mg Injection

General Information

Contains

Marketer

Storage

Product introduction

Uses of Biophenox Injection

Benefits of Biophenox Injection

How to use Biophenox Injection

How Biophenox Injection works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

How long should Biophenox 50mg Injection be taken?

Who should not use Biophenox 50mg Injection?

How does Biophenox 50mg Injection cause tachycardia?

Why is Biophenox 50mg Injection used for pheochromocytoma?

What are the advantages of using Biophenox 50mg Injection in pheochromocytoma?

What are other uses of Biophenox 50mg Injection?

Can Biophenox 50mg Injection affect sex life?

What are the symptoms of overdose of Biophenox 50mg Injection?

How quickly does Biophenox 50mg Injection work?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Kidney Function Test

References

Patient concerns

I am a patient of hypertension

Some times I had lot of hypertension

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests