Decapeptyl Depot Injection
Written By Dr. Anuj Saini, MMST, MBBS
Reviewed By Dr. Varun Gupta, MD Pharmacology, MBBS
Last updated on 12 Nov 2024 | 01:11 AM (IST)
Decapeptyl Depot Injection is used in the treatment of prostate cancer. It is also used to treat endometriosis (endometrium of uterus grows excessively and causes symptoms like pain, heavy or irregular periods), and central precocious puberty (very early puberty).
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General Information
Contains
Triptorelin (3.75mg)
Marketer
Ferring Pharmaceuticals
Storage
Store in a refrigerator (2 - 8°C). Do not freeze.
The content is shown in English


Product introduction
Decapeptyl Depot Injection is given as an injection under the skin by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Hot flashes, weakness, increased sweating, fatigue, back pain, and erectile dysfunction are some very common side effects of this medicine. The long-term use of medicine may cause weakened bones and a reduction in bone mineral density. You are advised to take vitamin D and calcium supplements while taking this medicine. It might cause menstrual periods to stop for a period of 7- 12 weeks, inform your doctor if menstrual bleeding continues even during the treatment.
Before taking this medicine, inform your doctor if you have a history of drinking alcohol, smoking, and osteoporosis. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Hot flashes, weakness, increased sweating, fatigue, back pain, and erectile dysfunction are some very common side effects of this medicine. The long-term use of medicine may cause weakened bones and a reduction in bone mineral density. You are advised to take vitamin D and calcium supplements while taking this medicine. It might cause menstrual periods to stop for a period of 7- 12 weeks, inform your doctor if menstrual bleeding continues even during the treatment.
Before taking this medicine, inform your doctor if you have a history of drinking alcohol, smoking, and osteoporosis. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Uses of Decapeptyl Injection
- Prostate cancer
- Endometriosis
- Uterine fibroids
- Precocious puberty (premature puberty)
- Female infertility
Side effects of Decapeptyl Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Decapeptyl
- Weakness
- Increased sweating
- Back pain
- Paresthesia (tingling or pricking sensation)
- Hot flashes
- Erectile dysfunction
How to use Decapeptyl Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Decapeptyl Injection works
Decapeptyl Depot Injection reduces the amount of sex hormones (testosterone in men and estrogen in women). It works by decreasing the blood levels of testosterone in males. Decapeptyl Depot Injection also acts by shutting off hormones made by the ovaries (female reproductive organs), so the estrogen (one of the hormones that causes females to have periods) level is lowered.
All substitutes for Decapeptyl Depot Injection
For information purposes only. Consult a doctor before taking any medicine.
Quick tips
- Decapeptyl Depot Injection helps in the treatment of locally advanced or metastatic prostate cancer.
- It is given as an injection either under the skin or into a muscle.
- It may cause dizziness and visual disturbances. Don't drive or do anything that requires mental focus until you know how it affects you.
- It will cause menstrual periods to stop. Periods will resume 7-12 weeks after the final injection. Consult your doctor if you experience menstrual bleed despite treatment.
- Use non-hormonal methods of contraception such as condoms to prevent pregnancy during treatment, as this medicine may be harmful to a developing baby.
- Long term treatment may lead to bone loss and a higher risk of bone fractures, especially if you are a heavy drinker, a smoker, or have a family history of osteoporosis.
- It may also be used to treat endometriosis and precocious puberty (premature puberty).
Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Decapeptyl Depot Injection. Please consult your doctor.

Pregnancy
UNSAFE
Decapeptyl Depot Injection is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.

Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Decapeptyl Depot Injection during breastfeeding is not available. Please consult your doctor.

Driving
UNSAFE
Decapeptyl Depot Injection may cause side effects which could affect your ability to drive.
You may feel dizzy, tired or have problems with your eyesight such as blurred vision. This may affect your driving ability.
You may feel dizzy, tired or have problems with your eyesight such as blurred vision. This may affect your driving ability.

Kidney
CAUTION
Decapeptyl Depot Injection should be used with caution in patients with kidney disease. Dose adjustment of Decapeptyl Depot Injection may be needed. Please consult your doctor.

Liver
CAUTION
Decapeptyl Depot Injection should be used with caution in patients with liver disease. Dose adjustment of Decapeptyl Depot Injection may be needed. Please consult your doctor.

Fact Box
Chemical Class
Polypeptides
Habit Forming
No
Therapeutic Class
HORMONES
Action Class
Gonadotropin-releasing hormone (GnRH) Agonists
Related lab tests
References
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1410-11.
- Triptorelin pamoate. Slough, Berkshire: Ipsen Ltd.; 2010 [revised 17 Dec. 2016]. [Accessed 23 Jan. 2019] (online) Avaialble from:
- Triptorelin pamoate. Martigny, Switzerland: Debio RP; 2000 [Accessed Jul. 2014]. [Accessed 27 Mar. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:

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User feedback
Once A Month
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Once A Week
9%
Once A Day
9%
Twice A Month
6%
Patient concerns
Her bone age is 10 yrs 9 months . Can I give decapeptyl injection to stop puberty . She is very short Worried about bone density
Dr. Gopal Samdani
Paediatrics
There are many underlying causes of patient?s symptoms. Different cause needs different treatment. Specific treatment cannot be given unless we establish exact underlying cause. Final and perfect diagnosis cannot be done without doing clinical examination of patient. Please consult me or any other Paediatrician. will take detail history and will examine patient in detail. All information will be used to determine exact underlying cause of problem. Depending upon cause will prescribe you treatment.
2 times had miscarriage hypothyroidism positive 2cm endometriosis cyst with pcod and rest all test is normal recently gone through 3 month decapeptyl ink treatment but cyst is as usual as per cyst is so small kindly suggest best advice decapeptyl treatment start in nov. 2016 and. Took 3 injection of decapeptyl monthly and now period come and i re did ultrasound but no improvement in endometriosis cyst All test like Apla , Torch , chromosomal study are normal
Dr. Asmita Kaundal
Obstetrics and Gynaecology
endometrial cyst is small do not worry abt it. try to concieve. keep taking medicine for thyroid. and tab folic acid 5 mg once daily.
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: Ferring Pharmaceuticals
Address: K-28/1, ADDITIONAL MIDC , ANAND NAGAR , AMBERNATH - 421506 , INDIA
Address: K-28/1, ADDITIONAL MIDC , ANAND NAGAR , AMBERNATH - 421506 , INDIA
Vendor Details
Country of origin: Germany
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- Glucose - Postprandial
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid-19 Test (RT-PCR technique)
- LFT (Liver Function Test)
- Kidney Function Test
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid
- Vitamin B12
- C- Reactive Protein Quantitative
- Urine Culture and Sensitivity
- Serum Electrolyte
- Serum Calcium
- Creatinine
- Diabetes Screening
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hemoglobin
- Complete Haemogram
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