Difra Gel

Written By Dr. Betina Chandolia, MDS, BDS

Reviewed By Dr. Lalit Kanodia, MBA, MD Pharmacology

Last updated on 11 Nov 2024 | 01:11 AM (IST)

Difra Gel is a medication used in the treatment of mild to moderate acne. It prevents the formation of small pimples, blackheads and whiteheads on the skin. It reduces excessive oil production of the skin and reduces inflammation or cleans the blocked pores.

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1/2

15 gm Gel

General Information

Contains

Adapalene (0.1% w/w)

Marketer

Saga Laboratories

Storage

Store below 30°C

The content is shown in English

Product introduction

Application of Difra Gel to the affected area once a day at bedtime is recommended. Avoid unnecessary sun exposure and cover the treated areas with clothing or use a sunscreen before stepping out in the sun. Drink plenty of water and use moisturizer as it may lead to dryness of mouth, lips and eyes. It may make your skin more fragile. It is advised, not to have any cosmetic procedures during the treatment.

Difra Gel should not be used during pregnancy. It may lead to birth defects, do consult your doctor if you are pregnant or planning to get pregnant.

Uses of Difra Gel

Acne

Benefits of Difra Gel

Acne
Difra Gel helps treat acne (commonly called pimples) by reducing the production of excessive oil in the skin that causes acne. It usually takes a few weeks to have a noticeable effect so keep using it even if it appears not to be working. Sometimes acne may get worse before it gets better, however, with proper use, your skin will get clearer. The earlier you start using it, the less likely you are to get scars. This medicine will help improve your mood and uplift your confidence as your skin becomes acne free.

Side effects of Difra Gel

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Difra

Erythema (skin redness)
Dry skin
Skin peeling
Skin burn
Itching

How to use Difra Gel

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the gel. Wash your hands after applying, unless hands are the affected area.

How Difra Gel works

Difra Gel is a form of vitamin A which treats acne (pimples). It works by preventing accumulation of the sebum (skin’s natural oil) which unblocks the pores and allows natural exfoliation of the outer layers of skin.

All substitutes for Difra Gel

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Difra Gel helps treat mild to moderate acne.
Apply it to the affected area once a day at bedtime.
Avoid exposure to strong sunlight and artificial UV light. Use of sunscreen products (non-comedogenic) and protective clothing over the treated area is recommended.
Avoid getting it in your eyes or mouth. If this happens, rinse with water immediately.
Do not apply to broken, sunburnt or sensitive areas of skin. Inform your doctor if you notice unusual dryness, redness and peeling of the skin.
Avoid getting any cosmetic procedures done without consulting your doctor first.
Do not use Difra Gel if you are pregnant or planning pregnancy.

Safety advice

Alcohol

No interaction found/established

Pregnancy

CONSULT YOUR DOCTOR

Difra Gel may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Difra Gel during breastfeeding is not available. Please consult your doctor.

Driving

No interaction found/established

Kidney

No interaction found/established

Liver

No interaction found/established

Frequently asked questions

Is Difra Gel safe to be used in pregnancy?

No, Difra Gel should not be used during pregnancy. However, if during the treatment you became pregnant, discontinue the medicine immediately and consult your doctor. Do not plan a pregnancy while using Difra Gel.

Is it safe to undergo cosmetic procedures while using Difra Gel?

It is advisable not to undergo cosmetic procedures while using Difra Gel. As cosmetic products with an abrasive, drying, or peeling action may cause an increased irritant effect. Consult your doctor if you are not sure.

Is it normal to have a burning sensation after applying Difra Gel?

Yes, it is common to experience burning sensation with the use of Difra Gel. You may also experience redness, drying, and scaling during the first 4 weeks of treatment which usually lessen with continued use of Difra Gel. Inform your doctor if the side effects bother you or do not improve.

How long does it take to see results from Difra Gel?

You may start noticing an improvement after two weeks of therapy, but a minimum of eight weeks are required to notice consistent beneficial effects.

How does Difra Gel help acne?

Difra Gel has anti-inflammatory action which reduces soreness and irritation. It is used for the treatment of acne of the face, chest, or back and may also help in reducing blackheads, and whiteheads. It helps in the treatment of abnormal skin processes associated with acne.

Can I use moisturiser after Difra Gel?

Moisturizers may be used, if necessary; however, products containing alpha hydroxy or glycolic acids should be avoided.

How should Difra Gel be applied?

Difra Gel should be applied at night before going to bed or should be used as directed by your doctor. Clean the affected area with water and make sure it is dry before applying Difra Gel. Take a small amount onto your fingertips and spread a thin layer over the entire face and any other affected areas. It is important to clean your hands after applying Difra Gel.

What precautions do I need to follow while using Difra Gel?

You need to be cautious while applying Difra Gel. Avoid contact with the eyes, lips, angles of the nose, and inside of the mouth. This medication should not be applied to cuts, abrasions, inflamed or reddened skin, and sunburned skin. Wax epilation should not be performed on treated skin, as it may cause skin erosions.

What should I avoid while using Difra Gel?

Difra Gel makes skin sensitive, so you should avoid spending time in sunlight. If you have to be in sunlight, you should wear sunscreen and wear a hat and clothes that cover the areas treated with Difra Gel. You should avoid weather extremes such as wind and cold, as this may cause irritation to your skin. Some skin products, such as harsh soaps, astringents, cosmetics that have strong skin drying effects, should be avoided. In addition, products containing high levels of alcohol should be avoided, as they may further dry or irritate your skin.

Can I use other acne products with Difra Gel?

Yes, you may use Difra Gel with other acne products such as benzoyl peroxide, erythromycin, and clindamycin when these products are applied in the morning. Difra Gel should be applied at night when it is being used with other acne treatment products.

Fact Box

Chemical Class

Retinoids

Habit Forming

Therapeutic Class

DERMA

Action Class

Retinoids- Third generation

References

Robertson DB, Maibach HI. Dermatologic Pharmacology. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 1056.
Burkhart C, Morrell D, Goldsmith L. Dermatological Pharmacology. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1810.
Sardana K, Madan A. How to Treat Acne. Sardana K, editor. In: Clinical Approach to Acne Vulgaris. 1st ed. New Delhi: CBS Publishers & Distributors Pvt. Ltd.; 2015. pp. 36-37.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 24-25.
Adapalene. Watford, Hertfordshire: Galderma (U.K) Ltd.; 1998 [revised May 2018]. [Accessed 29 Jan. 2019] (online) Available from:
Adapalene. Quebec, Canada: Galderma Production Canada Inc.; 2007. [Accessed 03 Apr. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 03 Apr. 2019] (online) Available from:
Adapalene [Prescribing Information]. Baie d’Urfé, QC: G Production Inc.; 2012. [Accessed 20 Feb. 2024] (online) Available from:

Patient concerns

Please suggest better treatment for acne and piles

Dr. Atul Jain

Dermatology

For acne-use Nadoxin gel at night over acne For piles-pls visit near general surgeon

This Prescription is given by A Dermatologist!! Please check it For my redness on skin

Dr. Atula Gupta

Dermatology

These medicines for acne

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Saga Laboratories
Address: survey no. 198/2 & 198/3, chachrawadi vasna, ta.: sanand, dist.: ahmedabad 382210, gujarat, india

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Difra Gel. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

Why we need a prescription?

Difra Gel

General Information

Contains

Marketer

Storage

Product introduction

Uses of Difra Gel

Benefits of Difra Gel

Side effects of Difra Gel

How to use Difra Gel

How Difra Gel works

All substitutes for Difra Gel

Adiff Gel

Adapan Gel

Derpalin 0.1% Gel

Acgel Nano Gel

Adsure Gel

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

Is Difra Gel safe to be used in pregnancy?

Is it safe to undergo cosmetic procedures while using Difra Gel?

Is it normal to have a burning sensation after applying Difra Gel?

How long does it take to see results from Difra Gel?

How does Difra Gel help acne?

Can I use moisturiser after Difra Gel?

How should Difra Gel be applied?

What precautions do I need to follow while using Difra Gel?

What should I avoid while using Difra Gel?

Can I use other acne products with Difra Gel?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

Patient concerns

Please suggest better treatment for acne and piles

This Prescription is given by A Dermatologist!! Please check it For my redness on skin

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

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