Grafeel Injection

Reviewed By Dr. Ashish Ranjan, MD (Pharmacology), MBBS

Last updated on 12 Nov 2024 | 01:10 AM (IST)

Grafeel Injection is used to prevent infections after chemotherapy. It is a growth factor that stimulates the bone marrow to produce white blood cells. These cells protect the body against infections.

Genuine

Authenticity Assured

Prescription

required

Cold stored

Stored between 2-8°C

₹1459 MRP ₹1504.033% off

General Information

Contains

Filgrastim (300mcg)

Marketer

Dr Reddy's Laboratories Ltd

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.

The content is shown in English

Product introduction

Grafeel Injection is given as an injection by a qualified medical professional. You should continue to take as long as your doctor advises for it. The duration of treatment varies according to your need and response to treatment. You might be asked to get regular tests done to check the number of blood cells in your blood and your bone density level while you are taking this medicine.

The most common side effects of this medicine include bone pain, weakness, headache, and rash. Other than this, pain or redness at the site of injection is common. But, inform your doctor if you notice a lump, swelling, or bruising that does not go away. It might not prevent you from all kinds of infection, hence inform your doctor if you notice fever, chills, rash, sore throat, and swelling around the face or neck.

Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Grafeel Injection

Prevention of Infections after chemotherapy

Benefits of Grafeel Injection

Prevention of Infections after chemotherapy
Grafeel Injection increases the production of white blood cells by stimulating the immune system in our body. White blood cells are those cells that help us to fight infections. This medicine is really effective and must be used under medical supervision. Avoid being in crowds and wash your hands often to prevent any infections. Have plenty of fluids, unless otherwise advised by the doctor not to.

Side effects of Grafeel Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Grafeel

Bone pain
Weakness
Headache
Rash
Nausea
Increased lactate dehydrogenase level in blood
Vomiting
Increased uric acid level in blood
Oropharyngeal pain
Hair loss
Fatigue
Diarrhea
Constipation
Decreased appetite
Cough
Breathing problems
Injection site reactions (pain, swelling, redness)

How to use Grafeel Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Grafeel Injection works

Grafeel Injection is a growth factor that stimulates the bone marrow to produce white blood cells. These cells protect the body against infections. .

All substitutes for Grafeel Injection

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Grafeel Injection reduces the risk of infection in people treated with chemotherapy.
It is usually given as a daily injection into the tissue just under the skin or into the vein.
You will normally receive your first dose at least 24 hours after your chemotherapy or bone marrow transplant.
Store it in the refrigerator, protect it from light, and don't shake it.
For a more comfortable injection, leave the syringe at room temperature for 30 minutes before using it.
Pain or redness in the area of injection is common. Let your doctor know if you notice a lump, swelling, or bruising that doesn't go away.
Use caution while driving or doing anything that requires concentration as Grafeel Injection may cause dizziness.
Your doctor may get regular tests done to monitor the number of blood cells in your blood, and your bone density level while you are receiving treatment with this medicine.
Stop taking Grafeel Injection and inform your doctor if you have a fever, shortness of breath, fast rate of breathing or trouble breathing.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Grafeel Injection. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Grafeel Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

SAFE IF PRESCRIBED

Grafeel Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving

UNSAFE

Grafeel Injection may cause side effects which could affect your ability to drive.
Grafeel Injection may cause fatigue. This may affect your driving ability.

Kidney

SAFE IF PRESCRIBED

Grafeel Injection is safe to use in patients with kidney disease. No dose adjustment of Grafeel Injection is recommended.

Liver

SAFE IF PRESCRIBED

Grafeel Injection is safe to use in patients with liver disease. No dose adjustment of Grafeel Injection is recommended.

Frequently asked questions

Is Grafeel Injection safe?

Grafeel Injection is safe if used at prescribed doses for the prescribed duration as advised by your doctor.

How does Grafeel Injection work?

Grafeel Injection works by stimulating the bone marrow (organ in the body where blood cells are produced) to increase the production of specific types of blood cells called neutrophils that help fight infections.

What are the uses of Grafeel Injection?

Grafeel Injection is used during cancer treatment (chemotherapy), bone marrow transplantation, severe chronic neutropenia (low number of a type of white blood cells called neutrophils), neutropenia in patients with HIV infection, and before stem cell donation.

Does Grafeel Injection cause cancer?

No, Grafeel Injection does not cause cancer.

Why does Grafeel Injection cause bone pain?

The exact cause in unknown, but bone pain is a common side-effect of Grafeel Injection.

Fact Box

Chemical Class

Granulocyte Colony-Stimulating Factor

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Granulocyte-colony stimulating factor (G-CSF)

Related lab tests

Complete Blood Count

Peripheral Smear Examination

References

Kaushansky K, Kipps TJ. Hematopoietic Agents: Growth Factors, Minerals, and Vitamins. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1074-75.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 545-46.
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Filgrastim. [Updated 2019 Jun 3]. [Accessed 18 Feb. 2020] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:

User feedback

Patients taking Grafeel Injection

Once A Day

37%

Once A Month

23%

Once A Week

12%

Twice A Month

11%

Twice A Week

Thrice A week

Alternate Day

Twice A Day

What are you using Grafeel Injection for?

Others

100%

Patient concerns

Plz check the report and reply She is my wife report one of hospital where operated the tumot operation and one of from delhi srl and last one from tmh mumbai After the diagnosis docror advice rediation now 1 st rediation therapy is finished and doctor giving now nublast 250mg tab So plz check the report and tell me as per the tata memorial final report what is the condition for patient She can live normal life or she can dead in ahead Doctor tells with my family she can live with treatment more than 1 to 2 years Is it right or wrong

Dr. Vijay Sharnangat

Medical Oncology and Hematology

You are on right treatmentAfter completion of radiation therapy you need to take chemotherapyThat tablet is the chemotherapy

What is symptomatic after chemotherapy for metastatic spine

Dr. Vijay Sharnangat

Medical Oncology and Hematology

Back pain is main symptom which you can get after disease progression

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Dr Reddy's Laboratories Ltd
Address: Dr. Reddy's Laboratories Ltd., Village Malpur, P.O.Bhud, Baddi, Dist. Solan, H.P.

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Provide right medicines

Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose

In accordance with the law

Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945

Grafeel Injection

General Information

Contains

Marketer

Storage

Product introduction

Uses of Grafeel Injection

Benefits of Grafeel Injection

Side effects of Grafeel Injection

How to use Grafeel Injection

How Grafeel Injection works

All substitutes for Grafeel Injection

Neukine 300mcg Injection

Endokine 300mcg Injection

Colstim Injection

Lupifil 300mcg Injection

Zystim 300mcg Injection

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

Is Grafeel Injection safe?

How does Grafeel Injection work?

What are the uses of Grafeel Injection?

Does Grafeel Injection cause cancer?

Why does Grafeel Injection cause bone pain?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Complete Blood Count

Peripheral Smear Examination

References

User feedback

Patients taking Grafeel Injection

What are you using Grafeel Injection for?

Patient concerns

What is symptomatic after chemotherapy for metastatic spine

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests