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Grenil 5mg/250mg Suspension
Domperidone (5mg)+ Paracetamol (250mg)
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Grenil 5mg/250mg Suspension is used to relieve migraine headaches and to treat nausea and vomiting associated with it. This medicine may also be used in ailments where fever is accompanied by vomiting.
Written By Dr. Betina Chandolia, MDS, BDS,
Reviewed By Dr. Lalit Kanodia, MBA, MD Pharmacology,
Last updated on 11 Nov 2024 | 01:08 AM (IST)
Written By Dr. Betina Chandolia, MDS, BDS,
Reviewed By Dr. Lalit Kanodia, MBA, MD Pharmacology,
Last updated on 11 Nov 2024 | 01:08 AM (IST)
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60 ml Suspension
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General Information
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Your child’s medicine at a glance
Give $ to your child orally, preferably 30 minutes before meals. Stick to the dose, time, and way prescribed by your doctor as that depends on your child’s clinical condition, body weight, and age. In case your child vomits within 30 minutes of taking this medicine, let the child calm down, and then repeat the dose.
Grenil 5mg/250mg Suspension should be given at the first sign of a migraine attack. If symptoms persist, further doses may be given but a gap of 4 hours must be maintained between each dose. However, never exceed the total dose that has been prescribed for a day.
Diarrhea, rash, restlessness, and drowsiness are some of the common yet temporary side effects of this medicine. Make sure to report to your child’s doctor if the side effects persist or become bothersome for your child.
Before giving this medicine to your child, let the doctor know if your child has had any previous episodes of medicine allergy, metabolic disorder, liver impairment, kidney malfunction, asthma, or blood disorder. This information is critical for dose alterations and for planning your child’s overall treatment.
Grenil 5mg/250mg Suspension should be given at the first sign of a migraine attack. If symptoms persist, further doses may be given but a gap of 4 hours must be maintained between each dose. However, never exceed the total dose that has been prescribed for a day.
Diarrhea, rash, restlessness, and drowsiness are some of the common yet temporary side effects of this medicine. Make sure to report to your child’s doctor if the side effects persist or become bothersome for your child.
Before giving this medicine to your child, let the doctor know if your child has had any previous episodes of medicine allergy, metabolic disorder, liver impairment, kidney malfunction, asthma, or blood disorder. This information is critical for dose alterations and for planning your child’s overall treatment.
Uses of Grenil 5mg/250mg Suspension in children
Benefits of Grenil 5mg/250mg Suspension for your child
Treatment of Migraine
Grenil 5mg/250mg Suspension is a combination of medicines that helps prevent migraine by changing the way that your nerves receive pain signals. It also blocks the action of chemicals in the body that can make you feel or be sick. This treats as well as prevents nausea or vomiting effectively. By preventing and reducing the frequency of headaches, it can help you carry out your daily activities and have a better quality of life.
Grenil 5mg/250mg Suspension is a combination of medicines that helps prevent migraine by changing the way that your nerves receive pain signals. It also blocks the action of chemicals in the body that can make you feel or be sick. This treats as well as prevents nausea or vomiting effectively. By preventing and reducing the frequency of headaches, it can help you carry out your daily activities and have a better quality of life.
Side effects of Grenil 5mg/250mg Suspension in children
Grenil 5mg/250mg Suspension does not pose serious side effects and is well-tolerated by children. In case the side effects do occur, they’re likely to subside once the body adapts to the medicine. Consult your child’s doctor if these side effects persist or bother your child. The most common side effects include-
Common side effects of Grenil
- Diarrhea
- Rash
- Restlessness
- Drowsiness
How can I give Grenil 5mg/250mg Suspension to my child?
Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Grenil 5mg/250mg Suspension is to be taken empty stomach.
How Grenil Suspension works
Grenil 5mg/250mg Suspension contains two medicines: Domperidone and Paracetamol. Domperidone is an antiemetic that works on the vomiting center in the brain. It also increases the movement of the muscles of the stomach and intestines, allowing food to move more easily through the stomach. This prevents nausea and vomiting caused due to migraines. Paracetamol is an analgesic (pain reliever) and an antipyretic (fever reducer) which blocks the release of certain chemical messengers that cause the pain associated with migraine.
All substitutes for Grenil 5mg/250mg Suspension
For information purposes only. Consult a doctor before taking any medicine.
Quick tips
- If diarrhea develops as a side effect, encourage your child to drink plenty of fluids.
- Never give any other medicines containing paracetamol along with this medicine as that may lead to serious side effects.
- Do not alter the dose by yourself as it can result in unwanted side effects in your child.
- Do not mix Grenil 5mg/250mg Suspension with any herbal or ayurvedic preparations as it will not be effective.
- Stop the medicine and report to the doctor on an immediate basis if your child exhibits side effects such as itching, breathing difficulty, and swelling of the face soon after taking Grenil 5mg/250mg Suspension.
- Grenil 5mg/250mg Suspension helps to ease the pain you feel during a migraine headache as well as helps to stop you from feeling sick.
- Dry mouth may occur as a side effect. Frequent mouth rinses, good oral hygiene, increased water intake and sugarless candy may help.
- Inform your doctor if you are taking any pain relief medicine.
- Grenil 5mg/250mg Suspension can only decrease the number and severity of attacks but may not completely stop them.
- Some tips that may help avoid a migraine attack:
- Have your meals at the same time every day.
- Avoid bright lights and extreme temperatures.
- Avoid loud music and noisy places.
- Avoid chocolates, cheese, processed food, alcohol, and smoking.
- Get sufficient sleep and avoid stress.
Safety advice

Kidney
SAFE IF PRESCRIBED
Grenil 5mg/250mg Suspension is safe to use in patients with kidney disease. No dose adjustment of Grenil 5mg/250mg Suspension is recommended.
However, dose adjustments may be required in severe kidney disease. Please consult with your child's doctor before giving the medicine to your child.
However, dose adjustments may be required in severe kidney disease. Please consult with your child's doctor before giving the medicine to your child.

Liver
CAUTION
Grenil 5mg/250mg Suspension should be used with caution in patients with liver disease. Dose adjustment of Grenil 5mg/250mg Suspension may be needed. Please consult your doctor.
However, the use of Grenil 5mg/250mg Suspension is not recommended in children with severe liver disease and active liver disease.
However, the use of Grenil 5mg/250mg Suspension is not recommended in children with severe liver disease and active liver disease.
Frequently asked questions
Children who have a recent history of gut surgery, have gastrointestinal obstruction or perforation, suffer from epilepsy, or are allergic to any of the ingredients of Grenil 5mg/250mg Suspension should avoid taking this medicine.
Children who are malnourished, suffering from a liver or kidney disease, heart disease, and electrolyte disturbances should remain cautious before taking Grenil 5mg/250mg Suspension. Also, children on antipsychotic medicines and those who have a history of atopic allergies such as hay fever, eczema, or asthma should consult the doctor before consuming Grenil 5mg/250mg Suspension. Always, consult your child’s doctor before giving Grenil 5mg/250mg Suspension in such cases.
Excess intake of Grenil 5mg/250mg Suspension is dangerous as it contains paracetamol which can cause serious liver damage (hepatotoxicity) and CNS side effects. Never give more than the prescribed dose to your child as it will not give fast relief rather it would result in serious adverse effects and can worsen your child’s condition.
Keep this medicine at room temperature in a dry place beyond the reach of the children.
Grenil 5mg/250mg Suspension can sometimes interact with other medicines or substances. Tell your doctor about any other medicines your child is taking before starting Grenil 5mg/250mg Suspension. Also, check with your child’s doctor before giving any medicine to your child.
Fact Box
Habit Forming
No
Therapeutic Class
NEURO CNS
References
- Royal United Hospitals Bath: NHS. Using Domperidone + Ibuprofen/Aspirin/Paracetamol for Migraine Attacks. 2017. [Accessed 22 Feb. 2021] (online) Available from:
- MacGregor EA, Wilkinson M, Bancroft K. Domperidone plus paracetamol in the treatment of migraine. Cephalalgia. 1993;13(2):124-7. [Accessed 22 Feb. 2021] (online) Available from:
- Ong JJY, De Felice M. Migraine Treatment: Current Acute Medications and Their Potential Mechanisms of Action. Neurotherapeutics 2018;15:274-90. [Accessed 22 Feb. 2021] (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: Karnataka Antibiotics & Pharmaceuticals Ltd
Address: Dr. Rajkumar Road Rajajinagar, 1st Stage Bangalore- 560 010 India
Address: Dr. Rajkumar Road Rajajinagar, 1st Stage Bangalore- 560 010 India
Vendor Details
Country of origin: India
A licensed vendor partner from your nearest location will deliver Grenil 5mg/250mg Suspension. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
A licensed vendor partner from your nearest location will deliver Grenil 5mg/250mg Suspension. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- Glucose - Postprandial
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid-19 Test (RT-PCR technique)
- LFT (Liver Function Test)
- Kidney Function Test
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid
- Vitamin B12
- C- Reactive Protein Quantitative
- Urine Culture and Sensitivity
- Serum Electrolyte
- Serum Calcium
- Creatinine
- Diabetes Screening
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hemoglobin
- Complete Haemogram
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