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Gynarich Injection

Written By Dr. Balshine Singh Kanwar, MD, MBBS
Reviewed By Dr. Ashish Ranjan, MD (Pharmacology), MBBS
Last updated on 12 Nov 2024 | 01:09 AM (IST)
Gynarich Injection is used in the treatment of hormone-dependent prostate cancer. It works by decreasing the blood levels of testosterone in males.
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General Information

Contains

Buserelin (4mcg/ml)

Marketer

Intas Pharmaceuticals Ltd

Storage

Store below 30°C
The content is shown in English
Gynarich Injection image

Product introduction

Gynarich Injection is given as an injection by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Decreased libido is one of the common side effects of this medicine. Inform your doctor if you notice swallowing or breathing problems, and swelling of your lips. Regular blood tests are required to check the level of liver enzymes, and fats (lipid level) in the body.

Before taking it, tell your doctor if you have heart disease, irregular heartbeat, and blood pressure. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Gynarich Injection

Side effects of Gynarich Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Gynarich
  • Decreased libido
  • Testicular atrophy
  • Increased sweating
  • Fatigue
  • Muscle weakness
  • Bone pain
  • Erectile dysfunction
  • Injection site pain

How to use Gynarich Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Gynarich Injection works

Gynarich Injection is a hormone similar to the one produced by a hypothalmus gland in the brain. It works by decreasing the blood levels of testosterone in males.

Quick tips

  • Gynarich Injection helps in the treatment of hormone-dependent prostate cancer.
  • It is given as an injection either under the skin.
  • It may cause dizziness and visual disturbances. Do not drive or do anything that requires mental focus until you know how it affects you.
  • If you are diabetic, monitor your blood glucose level regularly.
  • Inform your doctor if you suffer from high blood pressure or irregular heartbeat.

Safety advice

Alcohol

Alcohol

CAUTION
Caution is advised when consuming alcohol with Gynarich Injection. Please consult your doctor.
Pregnancy

Pregnancy

UNSAFE
Gynarich Injection is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Gynarich Injection during breastfeeding is not available. Please consult your doctor.
Driving

Driving

UNSAFE
Gynarich Injection may cause side effects which could affect your ability to drive.
As you may feel dizzy, drowsy or have blurred eyesight while using this medicine and this may affect your ability to drive.
Kidney

Kidney

CONSULT YOUR DOCTOR
There is limited information available on the use of Gynarich Injection in patients with kidney disease. Please consult your doctor.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited information available on the use of Gynarich Injection in patients with liver disease. Please consult your doctor.
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Frequently asked questions

This medicine slows or stops the growth of cancer cells and helps relieve symptoms such as painful/difficult urination.
Get medical help right away if you have signs of allergic reaction such as difficulty breathing, rash, hives, itching, and blisters. Also, let your doctor know if you experience severe headache, chest pain, fast/irregular heartbeat, severe dizziness, vision changes, and severe vomiting.
A tumor flare reaction is a sudden and an increase in the size of cancer as well as its symptoms. Yes, you might notice a TFR while taking Gynarich Injection and experience an increase in symptoms of prostate cancer such as blood in urine, painful or difficult urination, sudden back or trunk pain, or weakness in your legs, especially during the first month of the treatment. It is temporary and symptoms reduce gradually as treatment progresses. Talk to your doctor immediately if it does not.
Yes, you may put on weight when you are taking this medicine. Taking a balanced diet and being active can help you keep to a healthy weight.
Gynarich Injection may cause blood sugar levels to rise. Therefore, your doctor may adjust your dose of insulin or antidiabetic medicines accordingly. Monitor your blood sugar levels regularly and consult your doctor if you notice a sudden rise or notice symptoms like an increase in thirst and frequent urination.
Yes, an increase in sweating is a common side effect of this medicine and it usually stops a few months after treatment finishes. In order to get some relief, wear clothes made from natural fabrics, such as cotton; keep the room temperature cool or use an air conditioner; have cold drinks rather than hot ones, reduce the amount of alcohol you drink and stop smoking.
Yes, Gynarich Injection might lead to loss of sexual desire and cause erection problems as well. Things often return to normal after you stop taking the medicine. But some men continue to have problems even after treatment is over. Your doctor can prescribe treatments to help you cope up with it.
General tiredness/fatigue is a common side effect experienced during treatment with Gynarich Injection. You may need to adjust your schedule to manage fatigue. Take ample amounts of rest and do not indulge in physically exhausting activities. Exercise, such as walking, can help cope up with fatigue.
Gynarich Injection may make you dizzy and alcohol can make you dizzier. Limit your intake and consult your doctor for better advice.
Although Gynarich Injection may affect sperm quality, it is advisable to use contraceptives (condom, diaphragm) while being treated with this medicine. Tell your doctor right away if your partner becomes pregnant since Gynarich Injection may harm the baby.

Fact Box

Chemical Class

GNRH Analogue

Habit Forming

No

Therapeutic Class

HORMONES

Action Class

Gonadotropin-releasing hormone (GnRH) Agonists

Related lab tests

Anti Mullerian Hormone

Glycosylated Hemoglobin

Prostate Specific Antigen (Free) PSA

Prostate Specific Antigen (Total) PSA

Testosterone Total

Thyroid Stimulating Hormone

References

  1. BC Cancer Agency Cancer Drug Manual. Buserelin; 1994 [revised Mar. 2012]. [Accessed 26 Mar. 2019] (online) Available from:
  2. Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Intas Pharmaceuticals Ltd
Address: Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.

Vendor Details

Country of origin: India

Lab tests offered by us

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