Delivering to Gurgaon
Hi, there!
Login / Sign Up
Buy medicines
Buy health products
Book lab tests
Consult a doctor
1mg Care Plan
Cancer Care
Ayurveda
Partnerships
New
Hindi articles
Offers
All diseases
New
All medicines
Medicines by therapeutic class
Contact us
Need help?
Privacy policy
Return policy
Terms and conditions
Editorial policy
Get more features! Download the app now
Medicine Reminders
Monthly/weekly subscriptions
Health records and analysis
24*7 Emergency services
Download app on the App StoreDownload app on the Google play store
Choose city
Sign in to your account
or
By signing in you agree to our
Terms & conditions
 and 
Privacy policy

Isoniazid 300mg Tablet

Written By Dr. Love Sharma, PhD (Pharmacology), PGDPRA
Reviewed By Dr. Varun Gupta, MD Pharmacology, MBBS
Last updated on 12 Nov 2024 | 01:05 AM (IST)
Isoniazid 300mg Tablet is an antibiotic used for the treatment and prevention of tuberculosis (TB) and inactive (latent) TB (a serious infection caused by bacteria that affects the lungs and in certain cases other parts of the body). It works by killing the bacteria that cause tuberculosis.
Genuine
Authenticity Assured
Prescription
required
₹1.7 MRP ₹1.753% off 
Sku unavailable
 
 
0
footer-icon
efsr frrrrrr
aaa

General Information

Contains

Isoniazid (300mg)

Marketer

Cadila Pharmaceuticals Ltd

Storage

Store below 30°C
The content is shown in English
Isoniazid 300mg Tablet image

Product introduction

Isoniazid 300mg Tablet should be used in the dose and duration as advised by your doctor. It is to be taken on an empty stomach. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early can result in treatment failure and increase the side effects too. Do not take a double dose to make up for a missed dose. Simply take the next dose as planned.

Some common side effects of this medicine include tingling and numbness of feet and hand (peripheral neuropathy). Inform your doctor if you notice signs of jaundice, i.e., yellowing of eyes or skin, dark urine, stomach pain, or joint pain. You may also develop hepatitis (viral infection of the liver) or increased liver enzymes as side effects of this medicine. Please consult your doctor, as these side effects require medical attention and need dose modification.

Your doctor may monitor your liver function while on treatment with this medicine. Avoid drinking alcohol as this may have additional adverse effects on the liver. Pregnant or breastfeeding women should consult their doctor before using this medicine.

Uses of Isoniazid Tablet

Benefits of Isoniazid Tablet

Tuberculosis (TB)
Isoniazid 300mg Tablet is used to treat tuberculosis, an infectious disease that mainly affects the lungs but can affect other parts of the body as well. It kills and stops the growth of infection causing bacteria and helps in treating the infection. Take it in the dose and duration advised by the doctor. Your symptoms may improve before the infection is completely cured. Do not stop taking it without consulting your doctor as doing so may cause the infection to return or worsen. Follow your doctor’s instructions carefully to get maximum benefit.

Side effects of Isoniazid Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Isoniazid
  • Peripheral neuropathy (tingling and numbness of feet and hand)
  • Hepatitis (viral infection of liver)
  • Skin rash
  • Lethargy
  • Increased liver enzymes

How to use Isoniazid Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Isoniazid 300mg Tablet is to be taken empty stomach.
Avoid Isoniazid 300mg Tablet with tyramine-rich food such as cheese, smoked fish, meats and some types of beer.

How Isoniazid Tablet works

Isoniazid 300mg Tablet is an antibiotic. It works by killing the bacteria that causes tuberculosis.

Quick tips

  • Your doctor has prescribed Isoniazid 300mg Tablet to cure your infection and improve symptoms.
  • It is best taken on an empty stomach.
  • You must also take a vitamin B6 supplement while on Isoniazid 300mg Tablet.
  • Tell your doctor immediately if you experience vision changes, loss of appetite, tiredness, stomach pain, nausea or vomiting, yellow skin or eyes or dark-colored urine.

Safety advice

Alcohol

Alcohol

UNSAFE
Consuming alcohol while taking Isoniazid 300mg Tablet may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Isoniazid 300mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding

Breast feeding

SAFE IF PRESCRIBED
Isoniazid 300mg Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving

Driving

UNSAFE
Isoniazid 300mg Tablet may cause side effects which could affect your ability to drive.
Isoniazid 300mg Tablet can cause fits, mental health problems and optic neuritis (inflammation of the optic nerve that may cause loss of vision.) This may affect your driving ability.
Kidney

Kidney

SAFE IF PRESCRIBED
Isoniazid 300mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Isoniazid 300mg Tablet is recommended.
However, talk to your doctor if you have any underlying kidney disease.
Liver

Liver

CAUTION
Isoniazid 300mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Isoniazid 300mg Tablet may be needed. Please consult your doctor.
Use of Isoniazid 300mg Tablet is not recommended in patients with severe liver disease.
sljrsr jrjrrrrr

Frequently asked questions

Isoniazid 300mg Tablet is an antibiotic used in the prevention and treatment of tuberculosis or TB (a serious infection caused by bacteria that affects the lungs and in certain cases other parts of the body)
Isoniazid 300mg Tablet is a primary antibiotic used for treatment of tuberculosis. Do not confuse it with chemotherapy or chemo drugs used for the treatment of cancer
Isoniazid 300mg Tablet is a bacteriostatic antibiotic. It stops or suppresses growth of tuberculosis causing bacteria by interfering with the formation of protective outer covering (cell wall) which is essential for their growth
Yes. Isoniazid 300mg Tablet is safe if used at prescribed doses for the prescribed duration as advised by your doctor
Isoniazid 300mg Tablet has very weak inhibitory activity on enzymes monoamine oxidases (MAO); however it is not used as a monoamine oxidase inhibitor (MAOI)
No. The chemical structure and mechanism of action of Isoniazid 300mg Tablet is different from sulfa drugs
Isoniazid 300mg Tablet is an inhibitor (decreases activity) of an important liver enzyme system that is responsible for the final processing and elimination of several drugs from the body
There no known serious drug interactions of isoniazid with ibuprofen, paracetamol (trade name: Tylenol), naproxen (trade name: Aleve), amoxicillin or any active drug present in Nyquil or Mucinex. Please inform your doctor about all the medication you are currently taking to avoid interactions that may reduce effectiveness of any treatment or aggravate side effects
Changes in body weight (gain/loss), hair loss, diarrhea or changes in menstruation are not among the known side effects of Isoniazid 300mg Tablet. You may experience few of these side effects while on multi drug (including Isoniazid 300mg Tablet) treatment for tuberculosis
You may experience unusual tiredness, constipation or acne while on treatment with Isoniazid 300mg Tablet. Please inform your doctor about all the medication you are currently taking to avoid interactions that may reduce effectiveness of any treatment or aggravate side effects
Isoniazid 300mg Tablet has no known interaction with commonly used oral contraceptives (birth control pills). However, multidrug treatment for tuberculosis contains active drug rifampin that decreases the effectiveness of oral contraceptives and hampers birth control.

Fact Box

Chemical Class

Nicotinic acid derivatives

Habit Forming

No

Therapeutic Class

ANTI INFECTIVES

Action Class

Mycolic acid inhibitors- INH

Related lab tests

Complete Blood Count

Erythrocyte Sedimentation Rate

Mycobacterium Tuberculosis DNA PCR - Qualitative

Peripheral Smear Examination

References

  1. Gumbo T. Chemotherapy of Tuberculosis, Mycobacterium Avium Complex Disease, and Leprosy. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1555-558.
  2. Chambers HF, Deck DH. Antimycobacterial Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 824-25.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 741-42.
  4. Isoniazid. Nottingham, Nottinghamshire: Boots Contract Manufacturing; 2015. [Accessed 01 Apr. 2019] (online) Available from:
  5. Drugs.com. Isoniazid. [Accessed 01 Apr. 2019] (online) Available from:
  6. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 29 Mar. 2019] (online) Available from:
test
Related products
Products related to Isoniazid 300mg Tablet
4.4Rating star
Rotahaler Device
1 Rotahaler
₹135
₹139
3% off

₹122

order for
₹150
4.4Rating star
Lupihaler Inhaler
1 Inhaler
₹239
₹246
3% off

₹215

order for
₹150
4.4Rating star
Pulmocare Powder with Vitamins, Minerals & NAC for Respiratory & Lung Health | Flavour Strawberry
200 gm Powder
₹265
₹273
3% off

₹239

order for
₹150
4.6Rating star
Inhalade Drop
5 ml Drop
₹71.8
₹74
3% off

₹64.6

order for
₹150
Filvestin Tablet
10 tablets
₹427
₹440
3% off

₹384

order for
₹150
4.5Rating star
Aimil Jufex Forte Syrup (100ml Each)
1 ml Bottle
₹146
₹150
3% off

₹131

order for
₹150
4.5Rating star
Charak Cephagraine Tablet
40 tablets
₹110
₹113
3% off

₹99

order for
₹150
4.5Rating star
Lupihaler-T Inhaler
1 Inhaler
₹310
₹320
3% off

₹279

order for
₹150
4.7Rating star
Charak Spasma Syrup
200 ml Syrup
₹116
₹120
3% off

₹104

order for
₹150
KOLQ Capsule
10 capsules
₹51.9
₹53.5
3% off

₹46.7

order for
₹150
100% genuine products
100% genuine products
Safe & secure payments
Safe & secure payments
No contact delivery
No contact delivery
Fully sanitized facilities
Fully sanitized facilities

User feedback

Once A Day
100%
Tuberculosis (TB)
80%
Others
20%
Average
33%
Excellent
33%
Poor
33%
No Side Effect
67%
Jaundice
33%
Empty stomach
100%

Patient concerns

I had ectopic pregnancy as advice by dr.I had gone for laparoscopy for my other tube and after dat she gave me this medication ISONIAZID, PYRAZINAMIDE 750mg,PYRICO TIN, COMBUTOL600 which I had checked online dis all tablets r for TB so should I continue or stop

Dr. Sonu Balhara Ahlawat
Dr. Sonu Balhara Ahlawat
Obstetrics and Gynaecology
If u have been diagnosed with tuberculosis then start otherwise not

My daughter is given tb medicine even though she is not infected taking these medicine will cause tb???

Dr. Rahul Yadav
Dr. Rahul Yadav
Paediatrics
Hello, TB medicines are given only when there is indication of tuberculosis. They are for treating tuberculosis.
<h3 class=titleMediumExtraBold>Want to know more</h3>

Want to know more

We provide you with authentic, trustworthy and relevant information
<h3 class=titleMediumExtraBold>Have issue with the content</h3>

Have issue with the content

Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Cadila Pharmaceuticals Ltd
Address: Sarkhej-Dholka Road, Bhat, Ahmedabad-382 210, INDIA.

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?
Image of Step
Provide right medicines
Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose
Image of Step
In accordance with the law
Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945
close sheet