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Kabanat Injection

Written By Dr. Anuj Saini, MMST, MBBS
Reviewed By Dr. Lalit Kanodia, MBA, MD Pharmacology
Last updated on 11 Nov 2024 | 01:02 AM (IST)
Kabanat Injection belongs to the general group of medicines called antineoplastics. It is used for the treatment of advanced prostate cancer. It works by interfering with the growth of cancer cells, which are eventually destroyed.
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General Information

Contains

Cabazitaxel (60mg/ml)

Marketer

Natco Pharma Ltd

Storage

Store below 30°C
The content is shown in English
Kabanat Injection image

Product introduction

Kabanat Injection is given under the supervision of a healthcare professional and should not be self-administered. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. You should avoid drinking alcohol as it may increase your risk of liver damage.

The most common side effects of this medicine include Low red blood cell count, low platelet count, diarrhea, back pain, and hair loss. If they do not go away or get worse, tell your doctor. There may be ways of preventing or reducing these effects. It is very strong medicine and some people may develop serious side effects while taking it. This medicine may lower your ability to fight infections and lead to problems with your blood, liver or kidneys. Your doctor will advise you regular blood tests to check for these.

Before taking it, tell your doctor if you have liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. It may harm your baby. You and your partner should avoid becoming pregnant or fathering a child for several months after your treatment with it has stopped. Your doctor may perform several tests such as blood tests, and physical examinations both before and during treatment with this medicine.

Uses of Kabanat Injection

Benefits of Kabanat Injection

Prostate cancer
Prostate gland is a small walnut-sized gland that produces a fluid called seminal fluid that nourishes and transports sperms in males. The most common symptom of prostate cancer is difficulty with urination, but sometimes there are no symptoms at all. Kabanat Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells in men. This also relieves difficulty in passing urine and makes it easier for you to urinate.

Side effects of Kabanat Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Kabanat
  • Vomiting
  • Back pain
  • Weakness
  • Low blood platelets
  • Hair loss
  • Abdominal pain
  • Loss of appetite
  • Anemia (low number of red blood cells)
  • Diarrhea
  • Stomatitis (Inflammation of the mouth)
  • Blood in urine
  • Constipation
  • Cough
  • Taste change
  • Breathing problems
  • Decreased white blood cell count (neutrophils)
  • Nausea

How to use Kabanat Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Kabanat Injection works

Kabanat Injection is an anti-cancer medication. It works by damaging the genetic material (DNA) of the cancer cells and stops their growth and multiplication.

Quick tips

  • Kabanat Injection is given as an infusion into a vein (IV infusion) under the supervision of a doctor only.
  • Do not skip any dose and complete the course as suggested by your doctor.
  • Use an effective method of birth control to avoid pregnancy while taking this medication.
  • You may need to have blood tests to monitor your blood cells, platelets count, liver function and kidney function during treatment.
  • Inform your doctor immediately if you notice unusual bruising or bleeding or if you have dark, tarry, or bloody stools and sore throat.

Safety advice

Alcohol

Alcohol

UNSAFE
It is unsafe to consume alcohol with Kabanat Injection.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Kabanat Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Kabanat Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving

Driving

UNSAFE
Kabanat Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

SAFE IF PRESCRIBED
Kabanat Injection is safe to use in patients with kidney disease. No dose adjustment of Kabanat Injection is recommended.
Caution is advised in patients with severe kidney disease and end stage kidney disease as the information available is limited for use of this medicine in these patients.
Liver

Liver

CAUTION
Kabanat Injection should be used with caution in patients with liver disease. Dose adjustment of Kabanat Injection may be needed. Please consult your doctor.
Use of Kabanat Injection is not recommended in patients with severe liver disease.
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Frequently asked questions

Kabanat Injection is a chemotherapeutic drug (drug used for the management of cancer). It is, however, not a vesicant (drug which causes severe blisters on the skin).

Fact Box

Chemical Class

Taxanes Derivatives

Habit Forming

No

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Alkaloids-cytotoxic agents

Related lab tests

Prostate Specific Antigen (Free) PSA

Prostate Specific Antigen (Total) PSA

References

  1. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 176-78.
  2. Cabazitaxel. Oxford, Oxfordshire: Genzyme Therapeutics; 2011 [revised 03 Apr. 2017]. [Accessed 26 Mar. 2019] (online) Available from:
  3. Cabazitaxel. Bridgewater, New Jersey: Sanofi-aventis; 2010. [Accessed 26 Mar. 2019] (online) Available from:
  4. Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:
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Patient concerns

I have problem of frequent urination at night. My father had same at his time.Doctor told me that I am having BPH.Also I went through PSA whose result is 1.8 increased prostate gland size is 40 which came in ultrasound report .When doctor did some test by inserting his finger in my rectal area I felt abnormal pain.doctor asked me to go for a culture test so as to check which can be the best medicine for BPH for me. Kindly suggest if it can be something else like prostate cancer.

Dr. Vijay Sharnangat
Dr. Vijay Sharnangat
Medical Oncology and Hematology
May not be prostate cancer, it is only begnin enlargement of prostate.

Do i have prostrate cancer. Married but now having difficulty in having relation with wife. Penis not hard in the morning. Having problem with self spontaneous erection. Please help. God Bless.

Dr. Sanjay Singh Rai
Dr. Sanjay Singh Rai
Medical Oncology and Hematology
Not a symptom of prostate cancer
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Natco Pharma Ltd
Address: Natco House, Road No.2, Banjara Hills, Hyderabad-500 034, India

Vendor Details

Country of origin: India

Lab tests offered by us

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