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Kyzific 40mg Tablet

Written By Dr. Lipika Khurana, PGDHHM, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 10 Nov 2024 | 01:05 AM (IST)
Kyzific 40mg Tablet is a prescription medication used to treat adults with a type of blood cancer called Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML). It targets and inhibits specific proteins that promote cancer cell growth and helps manage and control the progression of CML.
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1/2
60 tablets
 
 
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General Information

Contains

Asciminib (40mg)

Marketer

Novartis India Ltd

Storage

Store below 30°C
The content is shown in English
Kyzific 40mg Tablet image
Kyzific 40mg Tablet image
Kyzific 40mg Tablet image

Product introduction

Kyzific 40mg Tablet may be taken with or without food. Take it exactly as prescribed by your doctor. Try to take your medication at the same time every day for maximum benefits. Make sure to follow your doctor’s instructions regarding blood tests and other evaluations to monitor your response to the treatment.


Common side effects include nausea, diarrhea, headache, fatigue, and muscle pain. If you experience these symptoms, talk to your doctor. They may be able to offer strategies to manage these side effects and ensure they do not interfere with your treatment. Drinking plenty of water, eating small and frequent meals, and getting adequate rest can help alleviate some of these symptoms.


While on treatment with Kyzific 40mg Tablet avoid grapefruit and grapefruit juice, as they can interfere with the effectiveness of the medicine. Let your doctor know about all other medications, supplements, or herbal products you are taking, as this medicine can interact with other substances. Be cautious about activities that may increase your risk of bleeding or injury, as Kyzific 40mg Tablet can sometimes affect blood clotting. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their doctor to make sure it is safe for them.

Uses of Kyzific Tablet

Benefits of Kyzific Tablet

Treatment of Blood cancer (Chronic myeloid leukaemia)
Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML) is a type of blood cancer where there is an abnormal chromosome called the Philadelphia chromosome. Ph+ CML is a specific form of CML identified by the presence of this Philadelphia chromosome.

Kyzific 40mg Tablet works by specifically targeting the abnormal protein that causes cancer cell growth, helping to control the disease. This targeted approach not only improves the management of CML but also minimizes damage to healthy cells, leading to potentially fewer side effects compared to traditional treatments. This helps improve the patient's overall quality of life and treatment outcomes.

Side effects of Kyzific Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Kyzific
  • Upper respiratory tract infection
  • Musculoskeletal (bone, muscle or joint) pain
  • Fatigue
  • Nausea
  • Rash
  • Diarrhea
  • Low blood platelets
  • Increased triglyceride level in blood
  • Decreased white blood cell count (neutrophils)
  • Decreased hemoglobin
  • Elevated creatine kinase
  • Increased alanine aminotransferase
  • Increased lipase in the blood
  • Elevated levels of serum amylase

How to use Kyzific Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Kyzific 40mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Kyzific Tablet works

Kyzific 40mg Tablet works by blocking the action of an abnormal protein that signals cancer cells to multiply. This helps stop the spread of cancer cells.

Quick tips

  • Inform your doctor if you have a history of inflammation of your pancreas.
  • Tell your doctor if you have a history of heart problems or blood clots in blood vessels.
  • Inform your doctor if you are taking some other medications.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Kyzific 40mg Tablet. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Kyzific 40mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding

Breast feeding

CAUTION
Kyzific 40mg Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Kyzific 40mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney

Kidney

SAFE IF PRESCRIBED
Kyzific 40mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Kyzific 40mg Tablet is recommended.
Liver

Liver

SAFE IF PRESCRIBED
Kyzific 40mg Tablet is safe to use in patients with liver disease. No dose adjustment of Kyzific 40mg Tablet is recommended.

Frequently asked questions

Kyzific 40mg Tablet is used to treat adults with a certain type of blood cancer called Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML) in the chronic phase.
Kyzific 40mg Tablet should be taken exactly as prescribed by your healthcare provider, usually once or twice daily, with or without food. Swallow the tablets whole with water.
Serious side effects can include cardiovascular issues, liver problems, and pancreatitis. If you experience symptoms like chest pain, yellowing of the skin or eyes, or severe abdominal pain, seek medical attention immediately.
You should inform your doctor about all other medications and supplements you are taking, Kyzific 40mg Tablet can interact with other drugs, potentially affecting its effectiveness or causing side effects.
Avoid grapefruit and grapefruit juice, as they can interfere with Kyzific 40mg Tablet. Also, ensure regular blood tests and check-ups with your healthcare provider to monitor your response to the treatment and manage any potential side effects.

Fact Box

Habit Forming

No

Therapeutic Class

ANTI NEOPLASTICS

Related lab tests

Bcr-Abl Gene Translocation (Qualitative)

Bcr-Abl Gene Translocation (Quantitative)

Complete Blood Count

Peripheral Smear Examination

References

  1. Asciminib [Prescribing Information]. East Hanover, New Jersey: Novartis Pharmaceuticals Corporation; 2024. [Accessed 27 June 2024] (online) Available from:
  2. SCEMBLIX ® (Asciminib) [Product Information]. [Accessed 27 June 2024] (online) Available from:
  3. Asciminib [Prescribing Information]. East Hanover, New Jersey: Novartis Pharmaceuticals Corporation; 2021. [Accessed 27 June 2024] (online) Available from:

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Patient concerns

She is suffering from chronic myeloid leukemia

Dr. Deepak Kumar Soni
Dr. Deepak Kumar Soni
Ayurveda
Hi Kindly consult to Ayurvedic doctor at your local city area , face to face consult is needed.

Mh mother have blood cancer .recently she got her first induction chemotherapy.in CBC test Immature myeloid cells 18 percent what are indicate.is it serious .is it shown presence of cancer in blood old tell me

Dr. Ila Jain Khandelwal
Dr. Ila Jain Khandelwal
Pathology
Dear Mam Greetings from 1mg, The reports shows low hemoglobin and platelet count which can be due to chemotherapy.
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Novartis India Ltd
Address: Sandoz House, Shiv Sagar Estate, Worli Mumbai -400 018, India

Vendor Details

Country of origin: Switzerland
A licensed vendor partner from your nearest location will deliver Kyzific 40mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's â„ž and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

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