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Lepril 2.5mg Tablet

Written By Dr. Anuj Saini, MMST, MBBS
Reviewed By Dr. Varun Gupta, MD Pharmacology, MBBS
Last updated on 11 Nov 2024 | 01:04 AM (IST)
Lepril 2.5mg Tablet belongs to a group of medicines known as angiotensin-converting enzyme (ACE) inhibitors. It is widely used to treat high blood pressure and heart failure and may be prescribed after a heart attack. It also lowers the chances of having a heart attack or stroke.
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General Information

Contains

Enalapril (2.5mg)

Marketer

Johnlee Pharmaceuticals Pvt Ltd

Storage

Store below 30°C
The content is shown in English
Lepril 2.5mg Tablet image

Product introduction

Lepril 2.5mg Tablet can be prescribed either alone or in combination with other medicines. It should be taken on an empty stomach. This medicine should be taken at the same time each day to get the most benefit. It is important to continue taking it regularly even if you feel well or even if your blood pressure is controlled. Most people with high blood pressure do not feel ill, but if you stop taking this medicine, your condition could get worse. This is a widely used medicine and is considered safe for long-term use.

Making some changes in your lifestyle will also help lower your blood pressure. These may include regular exercise, losing weight, smoking cessation, reducing alcohol intake, and reducing the amount of salt in your diet as advised by your doctor. The most common side effects of this medicine include decreased blood pressure, cough, increased potassium level in blood, fatigue, weakness, and dizziness. Most of these are temporary and resolve with time. Talk to your doctor if any of the side effects bother you or do not go away.

Before taking this medicine, let your doctor know if you have any kidney or liver problems. Pregnant or breastfeeding mothers should also consult their doctor before taking it. Your doctor may check your kidney function, blood pressure, and potassium levels in your blood at regular intervals while you are taking this medicine.

Uses of Lepril Tablet

Side effects of Lepril Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Lepril
  • Decreased blood pressure
  • Cough
  • Increased potassium level in blood
  • Fatigue
  • Weakness
  • Dizziness

How to use Lepril Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Lepril 2.5mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Lepril Tablet works

Lepril 2.5mg Tablet is an angiotensin converting enzyme (ACE) inhibitor. It works by reducing stress on the heart and relaxing blood vessel so that blood flows more smoothly and the heart can pump blood more efficiently.

All substitutes for Lepril 2.5mg Tablet

For information purposes only. Consult a doctor before taking any medicine.

Dilvas 2.5 Tablet

by Cipla Ltd
₹2.09/tablet
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Enam 2.5 Tablet

by Dr Reddy's Laboratories Ltd
₹2.07/tablet
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<h3 class=bodySemiBold>Enam 2.5 Tablet</h3>

Nuril 2.5 Tablet

by USV Ltd
₹2.1/tablet
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<h3 class=bodySemiBold>Nuril 2.5 Tablet</h3>

Enapril 2.5 Tablet

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₹1.95/tablet
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Eneril 2.5mg Tablet

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Quick tips

  • It should be taken with or without food, preferably at the same time each day.
  • Lepril 2.5mg Tablet can make you feel dizzy for the first few days, so rise slowly if you have been sitting or lying down. You can also prefer taking it at bedtime to avoid dizziness throughout the day.
  • Let your doctor know about any cough, or throat irritation that does not go away.
  • It may increase the level of potassium in blood. Avoid taking potassium supplements and potassium-rich foods such as banana and broccoli.
  • Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Safety advice

Alcohol

Alcohol

UNSAFE
It is unsafe to consume alcohol with Lepril 2.5mg Tablet.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Lepril 2.5mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Lepril 2.5mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Use of Lepril 2.5mg Tablet immediately after childbirth should be avoided.
Driving

Driving

UNSAFE
Lepril 2.5mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Lepril 2.5mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Lepril 2.5mg Tablet may be needed. Please consult your doctor.
Liver

Liver

CAUTION
Lepril 2.5mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Lepril 2.5mg Tablet may be needed. Please consult your doctor.

Frequently asked questions

Lepril 2.5mg Tablet belongs to a group of medicines known as angiotensin-converting enzyme (ACE) inhibitors. It relaxes and widens the blood vessels, making it easier for the blood to pass through the vessels. As a result of this, the heart does not have to work more to push the blood. Since the workload on the heart is reduced, it helps to lower the blood pressure and thus reduces the risk of heart attack and stroke. It is also used for the treatment and prevention of congestive heart failure.
No, Lepril 2.5mg Tablet does not cause excessive urination (loss of water through urine). The use of Lepril 2.5mg Tablet may not affect normally functioning kidneys. However, damage to the kidneys may occur when Lepril 2.5mg Tablet is given with a diuretic (water pill, a medicine that increases the urine output). In such a case, either the diuretic should be discontinued or its dose should be reduced. If you have severe heart failure or your kidneys are already affected then there is a risk of kidney failure. However, timely and appropriate treatment can reverse the damage caused to kidneys.
In rare cases, Lepril 2.5mg Tablet may cause yellowing of skin and eyes, loss of appetite and an increase in liver enzymes. It can also cause considerable damage to the liver and even death. Therefore, if you experience any such symptoms, call your doctor immediately.
You have to be careful when taking Lepril 2.5mg Tablet with hydrochlorothiazide, as it can further decrease your blood pressure. You may also develop symptoms of kidney failure, such as a reduced amount of urine, swelling of your legs, ankles, and feet from retention of water. While some may experience unexplained shortness of breath, excessive drowsiness or fatigue, persistent nausea, confusion, pain or pressure in your chest and seizures (fits). These symptoms usually occur if there is substantial water or salt loss prior to starting Lepril 2.5mg Tablet. Therefore, if you face any such issues contact your doctor who will either advise you to discontinue hydrochlorothiazide or give a lower dose. The doctor may also advise you Lepril 2.5mg Tablet in very low doses when used in combination with hydrochlorothiazide.
You should avoid taking ibuprofen and Lepril 2.5mg Tablet together since there is a risk of kidney damage. Also, this combined usage may reduce the effectiveness of Lepril 2.5mg Tablet. Consult your doctor for an alternative to ibuprofen.
Lepril 2.5mg Tablet starts reducing blood pressure within few hours. However, it may take few weeks to see full benefits. You may not notice any difference after taking Lepril 2.5mg Tablet for high blood pressure, it can only be noticed when you get your blood pressure checked. So, keep taking the medicine to feel better. If you are taking Lepril 2.5mg Tablet for heart failure, it may take few weeks to months before you start feeling better.
You may have to take Lepril 2.5mg Tablet for long time (even for life time), until and unless any serious side effect starts bothering and deters you from taking it. However, do not stop taking it without the advice of your doctor.
You should not stop taking Lepril 2.5mg Tablet without consulting your doctor. Doing this can suddenly increase your blood pressure which may cause a risk of heart attack or stroke. If you experience any side effects, talk to your doctor who will prescribe you another medicine.
Yes, Lepril 2.5mg Tablet is generally well tolerated by most people and can be taken for long term. However, its long-term use can sometimes cause your kidneys to not work properly. Your doctor will get regular blood tests done to check whether your kidneys are functioning properly or not.
Inform your doctor that you are taking Lepril 2.5mg Tablet, before surgery, especially when the use of general anesthetic (to put you to sleep) is recommended. This is done because Lepril 2.5mg Tablet can reduce your blood pressure when it is used with an anesthetic. Hence, your doctor may advise you to stop taking Lepril 2.5mg Tablet 24 hours before surgery.

Fact Box

Chemical Class

Dipeptides

Habit Forming

No

Therapeutic Class

CARDIAC

Action Class

Angiotensin-Converting Enzyme (ACE) Inhibitors

Related lab tests

Kidney Function Test

References

  1. Hilal-Dandan R. Renin and Angiotensin. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 733.
  2. Benowitz NL. Antihypertensive Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 182.
  3. Pfeffer MA, Opie LH. Inhibitors of the Renin-Angiotensin-Aldosterone System. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. pp. 141-42.
  4. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 463.
  5. Enalapril. Greenwood Village, Colorado: Silvergate Pharmaceuticals, Inc.; 1985 [revised Jan 2016]. [Accessed 18 Mar. 2019] (online) Available from:
  6. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 18 Mar. 2019] (online) Available from:
  7. Central Drugs Standard Control Organisation (CDSCO). Enalapril. [Accessed 18 Mar. 2019] (online) Available from:
  8. Enalapril maleate [Drug Label]. Steinbach, Canada: Valeant Pharmaceuticals International, Inc.; 2014. [Accessed 25 Jul. 2024] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Johnlee Pharmaceuticals Pvt Ltd
Address: 42/44, Babu Genu Road, Shop No. 06, 2nd Floor, Om Shanti Co-op Housing Society, Kalbadevi Road, Mumbai-400002. (India)

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Lepril 2.5mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's â„ž and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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