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Looz Enema

Written By Dr. Shreya Gupta, MDS (Oral Pathology & Microbiology), BDS
Reviewed By Dr. Lalit Kanodia, MBA, MD Pharmacology
Last updated on 12 Nov 2024 | 01:04 AM (IST)
Looz Enema is a type of sugar used to treat constipation. It is known as a laxative and makes your stool easier to pass by drawing water into your bowel. It is also used to treat hepatic encephalopathy (a liver disease causing confusion, tremor, decreased level of consciousness).
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General Information

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Product introduction

Looz Enema is given as an enema in patients who are hospitalized or are unable to take it by mouth. The most common side effects are application site irritation, nausea, and vomiting. These are usually mild and go away after a couple of days. You may also feel (or be) sick. You can help avoid the side effects by drinking plenty of fluids, taking your medicine between meals. Occasionally people develop serious side effects including severe stomach pain, severe diarrhea, mood changes, and seizures. Talk to your doctor straight away if you notice any of these.

Before taking this medicine, you should tell your doctor if you have diabetes or if you are unable to digest milk sugar (lactose intolerant). If you use this medicine over a long period of time, your doctor may want you to have occasional blood tests to check the mineral levels (e.g. potassium and sodium). Do not take other laxative medicines while taking this medicine and check with your doctor if you are pregnant or breastfeeding.

Uses of Looz Enema

  • Constipation
  • Intestine preparation before any surgery
  • Treatment of Hepatic encephalopathy

Benefits of Looz Enema

Treatment of Hepatic encephalopathy
Hepatic encephalopathy is a severe liver disease that can cause changes in brain function leading to confusion, tremors (shaking), sleep problems, and loss of consciousness. Looz Enema is thought to work by lowering the level of a substance called ammonia in the blood which has harmful effects on the brain. If taken as prescribed, it can improve your brain function and reduce symptoms associated with hepatic encephalopathy.

Side effects of Looz Enema

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Looz
  • Abdominal pain
  • Diarrhea
  • Nausea
  • Vomiting
  • Application site irritation

How to use Looz Enema

Your doctor or nurse will give you this medicine. Kindly do not self-administer.

How Looz Enema works

Looz Enema works by drawing water into the intestine through osmosis, which makes the stool soft and easier to pass.

Quick tips

  • Looz Enema is used in the treatment of constipation and hepatic encephalopathy.
  • It should preferably be taken at bedtime as it requires 6 to 8 hours to show effect.
  • It is usually taken once a day as needed for up to 2 weeks. Take it exactly as prescribed by the doctor.
  • Take it atleast 2 hours after taking other medicines, as it may interfere with the absorption of other medicines.
  • Inform your doctor if you have a history of stomach disorders such as appendicitis or a blockage in your bowel.
  • Some healthy tips to prevent constipation from happening:
    • Eat more fiber in your diet. Recommended daily intake is 20-35g
    • Drink 8-10 glasses of water per day
    • Exercise regularly at least 3 times per week
    • Do not hold in stool as that can worsen bowel issues
  • Looz Enema is used for the treatment of constipation.
  • Some healthy tips to prevent constipation from happening:
    • Eat more fiber in your diet. Recommended daily intake is 20-35g
    • Drink 8-10 glasses of water per day
    • Exercise regularly at least 3 times per week
    • Do not hold in stool as that can worsen bowel issues
  • Take it atleast 2 hours after taking other medicines, as it may interfere with the absorption of other medicines.
  • It should preferably be taken at bedtime as it requires 6 to 8 hours to show effect.
  • It is usually taken once a day as needed for up to 2 weeks. Take it exactly as prescribed by the doctor.
  • Inform your doctor if you have a history of stomach disorders such as appendicitis or a blockage in your bowel.

Safety advice

Alcohol

Alcohol

No interaction found/established
Pregnancy

Pregnancy

SAFE IF PRESCRIBED
Looz Enema is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breast feeding

Breast feeding

SAFE IF PRESCRIBED
Looz Enema is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving

Driving

No interaction found/established
Kidney

Kidney

SAFE IF PRESCRIBED
Looz Enema is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Looz Enema may not be needed in these patients. Please consult your doctor.
Liver

Liver

SAFE IF PRESCRIBED
Looz Enema is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Looz Enema may not be needed in these patients. Please consult your doctor.
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Frequently asked questions

Looz Enema is used to treat constipation which is presented as infrequent bowel movements, hard and dry stools. It is also used in patients with hepatic encephalopathy which is a serious liver problem causing confusion, tremors and decreased level of consciousness.
Yes, Looz Enema is a laxative which softens the stools by pulling in water from the body to the large intestine. It is also used to reduce the amount of ammonia in the blood of patients with liver disease.
Looz Enema very commonly causes diarrhea, flatulence, nausea, vomiting and abdominal pain. Diarrhea and abdominal pain occur due to a high dose. In such cases, the dose should be reduced. Flatulence may occur during the first few days of treatment and may disappear after sometime. This medicine may also cause electrolyte imbalance. However, this is an uncommon side effect.
You should take Looz Enema for as long as advised by your doctor. You may also take it for as long as constipation lasts, which may be up to a week. For hepatic encephalopathy, the treatment may be longer, even several months.
Looz Enema should not be given to patients who are allergic to it or are intolerant to lactose (cannot process lactose). It should also be avoided in patients having galactosemia, a rare health problem where the body cannot process galactose.
Usually, one laxative is sufficient to relieve constipation. In case you need more, your doctor may advise you to take one more laxative along with Looz Enema. The risk of side effects is more with two laxatives.

Fact Box

Chemical Class

Synthetic Disaccharide

Habit Forming

No

Therapeutic Class

GASTRO INTESTINAL

Action Class

Osmotic Laxatives / Purgatives

References

  1. Sharkey KA, Wallace JL. Treatment of Disorders of Bowel Motility and Water Flux; Anti-Emetics; Agents Used in Biliary and Pancreatic Disease. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1332.
  2. McQuaid KR. Drugs Used in the Treatment of Gastrointestinal Diseases. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 1079.
  3. Lactulose Solution [Prescribing Information]. Dieppe, New Brunswick: Sanis Health Inc.; 2015. [Accessed 30 Mar. 2020] (online) Available from:
  4. Drugs.com. Lactulose. [Accessed 30 Mar. 2010] (online) Available from:
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User feedback

Once A Day
72%
Twice A Day
19%
Thrice A Day
6%
Once A Month
2%
Constipation
88%
Others
12%

Patient concerns

Please tell me any liquid medicine to get rid of constipation.

Dr. Nabajit Talukdar
Dr. Nabajit Talukdar
Interventional Cardiology
Looz syp 30 ml daily bedtime

I have constipation problem. I always feel pain in my stomache because of it Sometimes i feel burning sensation in my upper abdomen. other problem related to it is stomache bloating. My ultrasound report is compltely fine. Please advise

Dr. Sfurti Mann
Dr. Sfurti Mann
Diabetology
Sompraz IT before breakfastSyp looz 15ml at night for constipation
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Intas Pharmaceuticals Ltd
Address: Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.

Vendor Details

Country of origin: India
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