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Luporal Capsule

Written By Dr. Anuj Saini, MMST, MBBS
Reviewed By Dr. Lalit Kanodia, MBA, MD Pharmacology
Last updated on 11 Nov 2024 | 01:00 AM (IST)
Luporal Capsule is a prescription medicine which is a combination of two anticancer medicines that is used in the treatment of cancer of the colon and rectum. It prevents the growth and multiplication of cancer cells, thus helps in destroying the tumor.
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General Information

Contains

Tegafur (100mg)+ Uracil (224mg)

Marketer

Lupin Ltd

Storage

Store below 30°C
The content is shown in English
Luporal Capsule image
Luporal Capsule image
Luporal Capsule image

Product introduction

Luporal Capsule may be taken with or without food. It should be used in the dose and duration as prescribed by your doctor. It is advised to take this medicine at a fixed time.

This medicine should not be taken more than the recommended dose. If you miss any dose, please consult your doctor. It is advised to complete the treatment without any interruption. This medicine is usually well tolerated by patients.

The common side effects of this medicine include nausea, vomiting, hair loss, low number of blood cells (anemia) and a decrease in white blood cell count. The doctor may ask you to undergo a few blood tests before or during the treatment.

Your doctor may prescribe you to undergo blood tests before or during the treatment. You may be given supplements to overcome the deficiency caused by this medicine. It is advised to add more vegetables and fruits in your diet to overcome any such deficiency.

This medicine is not safe to use in pregnancy. Inform your doctor if you are taking any other medicines or if you are breastfeeding. Inform your doctor if you are suffering from any disease. It is strictly advised not to drive or operate heavy machinery while you are on the treatment.

Uses of Luporal Capsule

Benefits of Luporal Capsule

Cancer of colon and rectum
Luporal Capsule treats cancer of the colon and rectum as well as lowers the risk of developing further cancerous growths. Using this medicine helps you recover more comfortably from chemotherapy. It is usually taken for 28 days (four weeks), followed by a seven day break. The cycle is then repeated. Follow your doctor's advice strictly during the entire treatment. Avoid drinking alcohol or smoking while having this treatment and drink plenty of water to stay hydrated.

Side effects of Luporal Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Luporal
  • Nausea
  • Vomiting
  • Tiredness
  • Mouth sore
  • Sore tongue
  • Stomach pain
  • Diarrhea
  • Loss of appetite
  • Decreased blood cells (red cells, white cells, and platelets)

How to use Luporal Capsule

Take this medicine in the dose and duration as advised by your doctor. Luporal Capsule may be taken with or without food, but it is better to take it at a fixed time.

How Luporal Capsule works

Luporal Capsule is a combination of two medicines: Tegafur and Uracil which treat cancer. They work by interfering with the growth of DNA and RNA of cancer cells by substituting their building blocks. This prevents the cancer cells from growing and multiplying.

All substitutes for Luporal Capsule

For information purposes only. Consult a doctor before taking any medicine.

Uratuf 100mg/224mg Capsule

by Dr Reddy's Laboratories Ltd
₹126/capsule
16% cheaper
<h3 class=bodySemiBold>Uratuf 100mg/224mg Capsule</h3>

Bdfucil 100mg/224mg Capsule

by BDR Pharmaceuticals Internationals Pvt
₹80.36/capsule
47% cheaper
<h3 class=bodySemiBold>Bdfucil 100mg/224mg Capsule</h3>

URACEL 100mg/224mg Capsule

by Celon Laboratories Ltd
₹106.79/capsule
29% cheaper
<h3 class=bodySemiBold>URACEL 100mg/224mg Capsule</h3>

Tagucil 100mg/224mg Capsule

by Celon Laboratories Ltd
₹141.6/capsule
6% cheaper
<h3 class=bodySemiBold>Tagucil 100mg/224mg Capsule</h3>

Tegasted Capsule

by Halsted Pharma Private Limited
₹165/capsule
9% costlier
<h3 class=bodySemiBold>Tegasted Capsule</h3>

Quick tips

  • Luporal Capsule is used for the treatment of cancer of the colon and rectum.
  • Avoid the use of antacids within 2 hours of taking this medicine.
  • Drink plenty of water every 24 hours after the start of the treatment.
  • You may be at risk of infection so try to avoid crowds or people with colds, and report fever or any other signs of infection immediately to your doctor.
  • To help treat/prevent mouth sores, use a soft toothbrush and rinse your mouth at least 3 times a day with saline water.
  • To reduce nausea, take anti-nausea medications as prescribed by your doctor, and eat small, frequent meals.
  • Eat foods that may help reduce diarrhea and take adequate rest.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Luporal Capsule. Please consult your doctor.
Pregnancy

Pregnancy

UNSAFE
Luporal Capsule is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Luporal Capsule during breastfeeding is not available. Please consult your doctor.
Driving

Driving

UNSAFE
Luporal Capsule may cause side effects which could affect your ability to drive.
Luporal Capsule may make you tired, nauseous or have blurred vision and this may affect your ability to drive.
Kidney

Kidney

CONSULT YOUR DOCTOR
There is limited information available on the use of Luporal Capsule in patients with kidney disease. Please consult your doctor.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited information available on the use of Luporal Capsule in patients with liver disease. Please consult your doctor.
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Fact Box

Habit Forming

No

Therapeutic Class

ANTI NEOPLASTICS

Related lab tests

Carcino Embryonic Antigen

References

  1. Central Drugs Standard Control Organisation (CDSCO). [Accessed 23 Apr. 2019] (online) Available from:
  2. Uracil-Tegafur. Bedfordview, South Africa: Bristol-Myers Squibb (Pty) Ltd; 2001. [Accessed 24 Apr. 2019] (online) Available from:
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Patient concerns

Is ulcers curable G2 stage of cancer in rectum area

Dr. Pawan Rawal
Dr. Pawan Rawal
Gastroenterology
Needs evaluation Please meet a Gastro surgeon

Colon cancer What treat many I have to give

Dr. Aanchal Maheshwari
Dr. Aanchal Maheshwari
Ayurveda
Complete reports along with the patient is need to be seen before starting the treatment
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Lupin Ltd
Address: 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India

Vendor Details

Country of origin: Taiwan

Lab tests offered by us

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