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Macloose 10gm Syrup

Written By Dr. Shreya Gupta, MDS (Oral Pathology & Microbiology), BDS
Reviewed By Dr. Lalit Kanodia, MBA, MD Pharmacology
Last updated on 08 Nov 2024 | 11:00 AM (IST)
Macloose 10gm Syrup is a type of sugar used to treat constipation. It is known as a laxative and makes your stool easier to pass by drawing water into your bowel. It is also used to treat hepatic encephalopathy (a liver disease causing confusion, tremor, decreased level of consciousness).
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General Information

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Macloose 10gm Syrup image

Product introduction

Macloose 10gm Syrup can be taken with or without food. You should take this medicine as advised by your doctor. Use this medicine regularly to get the maximum benefit and try to take it at the same time(s) each day. Your dose may go up or down depending on how well it is working. Do not take more than you are advised to and, if you miss a dose, do not take an extra one to make up for it. This medicine takes at least 48 hours to work. Talk to your doctor if you are still constipated after 3 days.

The most common side effects are nausea and vomiting. These are usually mild and go away after a couple of days. Occasionally people develop serious side effects including severe diarrhea and electrolyte imbalance. Talk to your doctor straight away if you notice any of these.

Before taking this medicine, you should tell your doctor if you have diabetes or if you are unable to digest milk sugar (lactose intolerant). If you use this medicine over a long period of time, your doctor may want you to have occasional blood tests to check the mineral levels (e.g. potassium and sodium). Do not take other laxative medicines while taking this medicine and check with your doctor if you are pregnant or breastfeeding.

Uses of Macloose Syrup

  • Constipation
  • Intestine preparation before any surgery
  • Treatment of Hepatic encephalopathy

Benefits of Macloose Syrup

Treatment of Hepatic encephalopathy
Hepatic encephalopathy is a severe liver disease that can cause changes in brain function leading to confusion, tremors (shaking), sleep problems, and loss of consciousness. Macloose 10gm Syrup is thought to work by lowering the level of a substance called ammonia in the blood which has harmful effects on the brain. If taken as prescribed, it can improve your brain function and reduce symptoms associated with hepatic encephalopathy.

Side effects of Macloose Syrup

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Macloose
  • Abdominal pain
  • Nausea
  • Vomiting
  • Diarrhea

How to use Macloose Syrup

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Macloose 10gm Syrup may be taken with or without food, but it is better to take it at a fixed time.

How Macloose Syrup works

Macloose 10gm Syrup works by drawing water into the intestine through osmosis, which makes the stool soft and easier to pass.

Quick tips

  • Macloose 10gm Syrup is used in the treatment of constipation and hepatic encephalopathy.
  • It should preferably be taken at bedtime as it requires 6 to 8 hours to show effect.
  • It is usually taken once a day as needed for up to 2 weeks. Take it exactly as prescribed by the doctor.
  • Take it atleast 2 hours after taking other medicines, as it may interfere with the absorption of other medicines.
  • Inform your doctor if you have a history of stomach disorders such as appendicitis or a blockage in your bowel.
  • Some healthy tips to prevent constipation from happening:
    • Eat more fiber in your diet. Recommended daily intake is 20-35g
    • Drink 8-10 glasses of water per day
    • Exercise regularly at least 3 times per week
    • Do not hold in stool as that can worsen bowel issues
  • Macloose 10gm Syrup is used for the treatment of constipation.
  • Some healthy tips to prevent constipation from happening:
    • Eat more fiber in your diet. Recommended daily intake is 20-35g
    • Drink 8-10 glasses of water per day
    • Exercise regularly at least 3 times per week
    • Do not hold in stool as that can worsen bowel issues
  • Take it atleast 2 hours after taking other medicines, as it may interfere with the absorption of other medicines.
  • It should preferably be taken at bedtime as it requires 6 to 8 hours to show effect.
  • It is usually taken once a day as needed for up to 2 weeks. Take it exactly as prescribed by the doctor.
  • Inform your doctor if you have a history of stomach disorders such as appendicitis or a blockage in your bowel.

Safety advice

Alcohol

Alcohol

SAFE
Consuming alcohol with Macloose 10gm Syrup does not cause any harmful side effects.
Pregnancy

Pregnancy

SAFE IF PRESCRIBED
Macloose 10gm Syrup is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breast feeding

Breast feeding

SAFE IF PRESCRIBED
Macloose 10gm Syrup is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving

Driving

SAFE
Macloose 10gm Syrup does not usually affect your ability to drive.
Kidney

Kidney

SAFE IF PRESCRIBED
Macloose 10gm Syrup is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Macloose 10gm Syrup may not be needed in these patients. Please consult your doctor.
Liver

Liver

SAFE IF PRESCRIBED
Macloose 10gm Syrup is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Macloose 10gm Syrup may not be needed in these patients. Please consult your doctor.
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Frequently asked questions

It takes about 2-3 days to see the benefits of the treatment. Talk to your doctor if you feel constipated even after 3 days of taking Macloose 10gm Syrup.
Macloose 10gm Syrup is used to treat constipation which is presented as infrequent bowel movements, hard and dry stools. It is also used in patients with hepatic encephalopathy which is a serious liver problem causing confusion, tremors and decreased level of consciousness.
Yes, Macloose 10gm Syrup is a laxative which softens the stools by pulling in water from the body to the large intestine. It is also used to reduce the amount of ammonia in the blood of patients with liver disease.
Macloose 10gm Syrup very commonly causes diarrhea, flatulence, nausea, vomiting and abdominal pain. Diarrhea and abdominal pain occur due to a high dose. In such cases, the dose should be reduced. Flatulence may occur during the first few days of treatment and may disappear after sometime. This medicine may also cause electrolyte imbalance. However, this is an uncommon side effect.
You should take Macloose 10gm Syrup for as long as advised by your doctor. You may also take it for as long as constipation lasts, which may be up to a week. For hepatic encephalopathy, the treatment may be longer, even several months.
Macloose 10gm Syrup should not be given to patients who are allergic to it or are intolerant to lactose (cannot process lactose). It should also be avoided in patients having galactosemia, a rare health problem where the body cannot process galactose.
Usually, one laxative is sufficient to relieve constipation. In case you need more, your doctor may advise you to take one more laxative along with Macloose 10gm Syrup. The risk of side effects is more with two laxatives.
You should take the prescribed amount in the measuring cup or spoon that is provided with the medicine. You can take it with water or fruit juice if you find it very sweet. Drink plenty of water for better results. Swallow it as soon as you keep it in mouth to prevent tooth decay which can occur if you take it for a longer time.

Fact Box

Chemical Class

Synthetic Disaccharide

Habit Forming

No

Therapeutic Class

GASTRO INTESTINAL

Action Class

Osmotic Laxatives / Purgatives

References

  1. Sharkey KA, Wallace JL. Treatment of Disorders of Bowel Motility and Water Flux; Anti-Emetics; Agents Used in Biliary and Pancreatic Disease. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1332.
  2. McQuaid KR. Drugs Used in the Treatment of Gastrointestinal Diseases. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 1079.
  3. Lactulose. Maidenhead, Berkshire: Intrapharm Laboratories Limited; 2015 [revised 12 Jan. 2017]. [Accessed 27 Mar. 2019] (online) Available from:
  4. Drugs.com. Lactulose. [Accessed 27 Mar. 2019] (online) Available from:
  5. Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:
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Patient concerns

hepatic encephalopathy fro 12 October

Dr. Saurav Arora
Dr. Saurav Arora
Homeopathy
Dear sir as your case is a chronic case it requires long case taking, examination and regular follow up, therefore, please visit a homeopath so that he can examine you and guide you accordingly.

Jaundice liver cirrhosis. Hepatic encephalopathy and ascites not edema with Sodium 107. Can we use tolvaptone?

Dr. Gurpreet Singh
Dr. Gurpreet Singh
Physician
Sir consult a hepatologist
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Pray Healthcare
Address: SCF-283, Ist Floor, Sector-13, Manimajra, Chandigarh-160101

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Macloose 10gm Syrup. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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