Milrinol Injection
Written By Dr. Anuj Saini, MMST, MBBS
Reviewed By Dr. Varun Gupta, MD Pharmacology, MBBS
Last updated on 12 Nov 2024 | 01:02 AM (IST)
Milrinol Injection is a medicine used for short-term treatment of heart failure. It is also used to treat patients with a poorly functioning heart after heart surgery. It makes the heart pump blood more efficiently.
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General Information
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Product introduction
It is administered under the supervision of a doctor. Your doctor will decide the dose and duration of the medicine for you. The doctor may closely monitor your blood pressure, heart rate, and ECG until you become stable. You should continue all your other medicines that are advised by the doctor for your long-term treatment even after this injection.
Common side effects of this medicine include hypotension, headaches, arrhythmias, and tachycardia. Consult your doctor if these effects bother you. This medicine is used with caution for some people. Thus, you must inform the doctor if you are suffering from any kidney disease. Also, let your doctor know if you are pregnant or breastfeeding and about all the other medications that you are taking regularly.
Common side effects of this medicine include hypotension, headaches, arrhythmias, and tachycardia. Consult your doctor if these effects bother you. This medicine is used with caution for some people. Thus, you must inform the doctor if you are suffering from any kidney disease. Also, let your doctor know if you are pregnant or breastfeeding and about all the other medications that you are taking regularly.
Uses of Milrinol Injection
Benefits of Milrinol Injection
Heart failure
Heart failure means your heart is weak and cannot pump enough blood to your lungs and the rest of your body. The most common symptoms are breathlessness, tiredness, and swelling in your legs, ankles, abdomen and other parts of your body. Milrinol Injection makes it easier for your heart to pump blood around your body and is therefore an effective treatment for heart failure.
This medicine will help relieve your symptoms, making you feel better and more energetic. You should make appropriate lifestyle changes (such as eating healthily and keeping active) to help this medicine be effective. Follow your doctor’s instructions carefully to get maximum benefit.
Heart failure means your heart is weak and cannot pump enough blood to your lungs and the rest of your body. The most common symptoms are breathlessness, tiredness, and swelling in your legs, ankles, abdomen and other parts of your body. Milrinol Injection makes it easier for your heart to pump blood around your body and is therefore an effective treatment for heart failure.
This medicine will help relieve your symptoms, making you feel better and more energetic. You should make appropriate lifestyle changes (such as eating healthily and keeping active) to help this medicine be effective. Follow your doctor’s instructions carefully to get maximum benefit.
Side effects of Milrinol Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Milrinol
- Hypotension (low blood pressure)
- Headache
- Arrhythmia (irregular heartbeats)
- Tachycardia
How to use Milrinol Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Milrinol Injection works
Milrinol Injection is a vasodilator. It increases the level of a chemical messenger (cAMP), which helps the smooth muscles to relax. Thus, dilates the blood vessels for better blood flow into the heart. It also has blood thinning property.
Quick tips
- If mild burning or pain at the injection site bothers you consult with your doctor.
- Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Milrinol Injection. Please consult your doctor.

Pregnancy
CONSULT YOUR DOCTOR
Milrinol Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding
SAFE IF PRESCRIBED
Milrinol Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving
CONSULT YOUR DOCTOR
It is not known whether Milrinol Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Kidney
CAUTION
Milrinol Injection should be used with caution in patients with kidney disease. Dose adjustment of Milrinol Injection may be needed. Please consult your doctor.

Liver
SAFE IF PRESCRIBED
Milrinol Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Milrinol Injection may not be needed in these patients. Please consult your doctor.

Fact Box
Chemical Class
Bipyridines and Oligopyridines Derivative
Habit Forming
No
Therapeutic Class
CARDIAC
Action Class
Phosphodiesterase-III inhibitors (HF)
References
- Maron BA, Rocco TP. Pharmacotherapy of Congestive Heart Failure. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 805.
- Teerlink JR, Sliwa K, Opie LH. Heart Failure. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. pp. 181-83.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 921-22.
- Milrinone. Guildford, Surrey: SANOFI; 1989 [revised 19 Jun. 2018]. [Accessed 19 Mar. 2019] (online) Available from:
- Drugs.com. Milrinone Pregnancy and Breastfeeding Warnings. [Accessed 19 Mar. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:

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Patient concerns
What is BNP test? Pls explain. What is BNP ASSAY?My result is133.0 explain
Dr. Manju Singh
Homeopathy
BNP levels below 100 pg/mL indicate no heart failure. BNP levels of 100-300 pg/mL suggest heart failure is present. BNP levels above 300 pg/mL indicate mild heart failure. BNP levels above 600 pg/mL indicate moderate heart failure.The level of BNP in the blood increases when heart failure symptoms worsen, and decreases when the heart failure condition is stable
Myself is high B.P patients .There is some swelling in the face today . what is going on?
Dr. Pushkar Mani
Physician
Kidney damage or heart failure
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: Biogen Serums Pvt Ltd
Address: R6 Sector, A 104, Life Republic Marunji, Hinjewadi - 411057
Address: R6 Sector, A 104, Life Republic Marunji, Hinjewadi - 411057
Vendor Details
Country of origin: India
A licensed vendor partner from your nearest location will deliver Milrinol Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
A licensed vendor partner from your nearest location will deliver Milrinol Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- Glucose - Postprandial
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid-19 Test (RT-PCR technique)
- LFT (Liver Function Test)
- Kidney Function Test
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid
- Vitamin B12
- C- Reactive Protein Quantitative
- Urine Culture and Sensitivity
- Serum Electrolyte
- Serum Calcium
- Creatinine
- Diabetes Screening
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hemoglobin
- Complete Haemogram
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