Myobid 250 Tablet

Written By Dr. Love Sharma, PhD (Pharmacology), PGDPRA

Reviewed By Dr. Shilpa Garcha, MD (Pharmacology), MBBS

Last updated on 09 Nov 2024 | 01:00 AM (IST)

Myobid 250 Tablet is an antibiotic that belongs to a class of medicines known as anti tuberculosis drugs. It is used in the treatment and prevention of tuberculosis, an infectious disease that mainly affects the lungs and in some cases other parts of the body.

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₹156 MRP ₹160.43% off

General Information

Contains

Ethionamide (250mg)

Marketer

Panacea Biotec Pharma Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Myobid 250 Tablet is usually given in combination with at least one other tuberculosis medicine. It is used in cases where bacteria have developed resistance to other antibacterial medicines. It should be used in the dose and duration as advised by your doctor. This medicine may be taken with or without food, preferably at the same time every day. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early can result in treatment failure and in the development of drug-resistant tuberculosis. This can lead to serious health complications.

If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose, as it may increase the side effects.

Some people may experience loss of appetite, nausea, vomiting, gastric irritation (inflammation of the stomach lining) and sudden lowering of blood pressure on standing (orthostatic hypotension), as side effects of this medicine. Please consult your doctor if these side effects worry you or do not get better.

Inform your doctor if you have diabetes as it can lower the sugar levels in the blood. If you are diabetic, you should monitor your blood sugar regularly. Your doctor may monitor your liver function, vision, and thyroid function while on treatment with this medicine. Pregnant or breastfeeding women should consult their doctor before using this medicine.

Uses of Myobid Tablet

Tuberculosis (TB)

Benefits of Myobid Tablet

Tuberculosis (TB)
Myobid 250 Tablet is used to treat tuberculosis, an infectious disease that mainly affects the lungs but can affect other parts of the body as well. It stops the growth of infection causing bacteria and helps in treating the infection. Take it in the dose and duration advised by the doctor. Your symptoms may improve before the infection is completely cured. Do not stop taking it without consulting your doctor as doing so may cause the infection to return or worsen. Follow your doctor’s instructions carefully to get maximum benefit.

Side effects of Myobid Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Myobid

Loss of appetite
Nausea
Vomiting
Gastric irritation
Orthostatic hypotension (sudden lowering of blood pressure on standing)
Weakness
Depression
Sleepiness

How to use Myobid Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Myobid 250 Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Myobid Tablet works

Myobid 250 Tablet is an antibiotic. It works by slowing the growth of bacteria that causes tuberculosis.

Quick tips

Myobid 250 Tablet is effective at treating tuberculosis when taken together with other antibacterial drugs.
It has to be taken for several months in order for it work properly (usually 6 months).
Take it with food to avoid stomach upset.
It can lower your blood sugar. If you have diabetes, monitor your blood sugar regularly.
Your doctor may monitor your liver function, vision and thyroid function while on treatment with this medicine.
Avoid consuming alcohol while taking this medication.
Do not stop taking Myobid 250 Tablet even if you start to feel better. Stopping early can result in treatment failure and in the development of drug-resistant tuberculosis. This can be life-threatening and lead to other serious health risks.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Myobid 250 Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Myobid 250 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Myobid 250 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Myobid 250 Tablet may cause side effects which could affect your ability to drive.
Myobid 250 Tablet may cause side effects such as drowsiness or a headache, that can impair your ability to drive.

Kidney

SAFE IF PRESCRIBED

Myobid 250 Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Myobid 250 Tablet may not be needed in these patients. Please consult your doctor.
Dose adjustment may be needed in patients with end stage kidney disease.

Liver

CAUTION

Myobid 250 Tablet should be used with caution in patients with liver disease. Dose adjustment of Myobid 250 Tablet may be needed. Please consult your doctor.
Use of Myobid 250 Tablet is not recommended in patients with the severe liver disease.

Frequently asked questions

What is Myobid 250 Tablet? What is it used for?

Myobid 250 Tablet is an antibiotic. It is used as a second-line medicine in combination with other anti-tuberculosis medicines for the treatment of all forms of tuberculosis caused by Mycobacterium tuberculosis.

Why is Myobid 250 Tablet called a second line drug?

Tuberculosis (TB) is a difficult infection to treat and when it is detected for the first time, first-line drugs are used. Generally, the appropriate use of first-line drugs (e.g. isoniazid, rifampicin, ethambutol, pyrazinamide, and streptomycin) can effectively cure TB. But, if the patient does not respond to first-line medicines, then second-line medicines (e.g. Myobid 250 Tablet, kanamycin, ciprofloxacin, etc.) are used. Second-line medicines have more side effects and are the second choice in terms of effectiveness.

Are there any precautions that I should take while taking Myobid 250 Tablet so that I respond to the treatment?

It is very important that you take the medicine exactly as directed by your doctor. Your doctor will prescribe at least two more medicines to be taken with Myobid 250 Tablet. Take all the prescribed medicines as per the instructions and do not miss or stop the treatment on your own. Missing doses and stopping the treatment without consulting the doctor are the major causes of treatment failure and drug resistance (not responding to the medication).

For how long do I need to take Myobid 250 Tablet?

Your doctor will decide the duration of your treatment depending upon your response to the treatment. The doctor will observe your maximum improvement by evaluating you clinically as well as your blood tests.

Why has my doctor asked me to get blood tests done regularly?

The blood tests are done to check if your liver is functioning properly or not, since Myobid 250 Tablet may affect your liver. Myobid 250 Tablet can also alter your blood glucose levels and thyroid hormone levels. Therefore, monitoring is required.

What are the symptoms which are suggestive of liver toxicity caused by Myobid 250 Tablet?

If you develop symptoms such as loss of appetite, nausea, jaundice (yellowing of the skin and eye white), dark urine, discolored stools, pain and tenderness in the upper right abdomen, inform your doctor immediately. These could be the signs of liver toxicity.

Is it necessary to take pyridoxine with Myobid 250 Tablet?

Pyridoxine is vitamin B6 that helps to prevent nerve damage, which may occur with the use of Myobid 250 Tablet. The symptoms of nerve damage are numbness, tingling, or pain in your hands or feet.

My friend is taking Myobid 250 Tablet and other medicines for TB. I have noticed that sometimes she acts very aggressively. Is it because of the disease or the treatment?

These changes could be due to Myobid 250 Tablet or other medicines that she is taking for TB. Myobid 250 Tablet may cause depression, confusion, aggression, abnormal thinking, and even hallucinations. You should speak to her family or doctor and help her out.

Fact Box

Chemical Class

Nicotinic acid derivatives

Habit Forming

Therapeutic Class

ANTI INFECTIVES

Action Class

Mycobacterial cell wall inhibitors-Ethambutol

Related lab tests

Complete Blood Count

Erythrocyte Sedimentation Rate

Mycobacterium Tuberculosis DNA PCR - Qualitative

Peripheral Smear Examination

References

Gumbo T. Chemotherapy of Tuberculosis, Mycobacterium Avium Complex Disease, and Leprosy. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1561-562.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 513-14.
Ethionamide. Philadelphia, PA: Wyeth Pharmaceuticals Inc.; 2016. [Accessed 19 Jun. 2019] (online) Available from:
Drugs.com. Ethionamide. [Accessed 01 Apr. 2019] (online) Available from:
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 29 Mar. 2019] (online) Available from:

User feedback

What are you using Myobid Tablet for?

Tuberculosis (TB)

100%

Patient concerns

My daughter is given tb medicine even though she is not infected taking these medicine will cause tb???

Dr. Rahul Yadav

Paediatrics

Hello, TB medicines are given only when there is indication of tuberculosis. They are for treating tuberculosis.

Though took vaccines in childhood, the test for TB came positive. Was advised to undergo treatment.physically absolute fit and healthy, is it advisable to take treatment?

Dr. Anshum Aneja Arora

Pulmonology

If sputum is positive for Tb , treatment is absolutely essential. Read more at www.arohealth.com/tuberculosis

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Panacea Biotec Pharma Ltd
Address: "Panacea Biotec Pharma Ltd B-1,Extn/A-27,Mohan Co-operative Industrial Estate Mathura Road, New Delhi-110044"

Vendor Details

Country of origin: India

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