Pethide 250mg Tablet
Written By Dr. Sakshi Sharma, BDS
Reviewed By Dr. Lalit Kanodia, MBA, MD Pharmacology
Last updated on 12 Nov 2024 | 01:12 AM (IST)
Pethide 250mg Tablet is an antibiotic that belongs to a class of medicines known as anti tuberculosis drugs. It is used in the treatment and prevention of tuberculosis, an infectious disease that mainly affects the lungs and in some cases other parts of the body.
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General Information
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Product introduction
Pethide 250mg Tablet is given in combination with at least one other tuberculosis medicine. It is used in cases where bacteria have developed resistance to other antibacterial medicines. It should be used in the dose and duration as advised by your doctor. This medicine may be taken with or without food, preferably at the same time every day. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early can result in treatment failure and in the development of drug-resistant tuberculosis. This can lead to serious health complications.
If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose, as it may increase the side effects.
Some people may experience loss of appetite, nausea, vomiting, gastric irritation (inflammation of the stomach lining) and sudden lowering of blood pressure on standing (orthostatic hypotension), as side effects of this medicine. Please consult your doctor if these side effects worry you or do not get better.
Inform your doctor if you have diabetes as it can lower the sugar levels in the blood. If you are diabetic, you should monitor your blood sugar regularly. Your doctor may monitor your liver function, vision, and thyroid function while on treatment with this medicine. Pregnant or breastfeeding women should consult their doctor before using this medicine.
If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose, as it may increase the side effects.
Some people may experience loss of appetite, nausea, vomiting, gastric irritation (inflammation of the stomach lining) and sudden lowering of blood pressure on standing (orthostatic hypotension), as side effects of this medicine. Please consult your doctor if these side effects worry you or do not get better.
Inform your doctor if you have diabetes as it can lower the sugar levels in the blood. If you are diabetic, you should monitor your blood sugar regularly. Your doctor may monitor your liver function, vision, and thyroid function while on treatment with this medicine. Pregnant or breastfeeding women should consult their doctor before using this medicine.
Uses of Pethide Tablet
Benefits of Pethide Tablet
Tuberculosis (TB)
Pethide 250mg Tablet is used to treat tuberculosis, an infectious disease that mainly affects the lungs but can affect other parts of the body as well. It stops the growth of infection causing bacteria and helps in treating the infection. Take it in the dose and duration advised by the doctor. Your symptoms may improve before the infection is completely cured. Do not stop taking it without consulting your doctor as doing so may cause the infection to return or worsen. Follow your doctor’s instructions carefully to get maximum benefit.
Pethide 250mg Tablet is used to treat tuberculosis, an infectious disease that mainly affects the lungs but can affect other parts of the body as well. It stops the growth of infection causing bacteria and helps in treating the infection. Take it in the dose and duration advised by the doctor. Your symptoms may improve before the infection is completely cured. Do not stop taking it without consulting your doctor as doing so may cause the infection to return or worsen. Follow your doctor’s instructions carefully to get maximum benefit.
Side effects of Pethide Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Pethide
- Loss of appetite
- Nausea
- Vomiting
- Gastric irritation
- Orthostatic hypotension (sudden lowering of blood pressure on standing)
- Depression
- Weakness
- Sleepiness
How to use Pethide Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pethide 250mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Pethide Tablet works
Pethide 250mg Tablet is an antibiotic. It works by slowing the growth of bacteria that causes tuberculosis.
Quick tips
- Pethide 250mg Tablet is effective at treating tuberculosis when taken together with other antibacterial drugs.
- It has to be taken for several months in order for it work properly (usually 6 months).
- Take it with food to avoid stomach upset.
- It can lower your blood sugar. If you have diabetes, monitor your blood sugar regularly.
- Your doctor may monitor your liver function, vision and thyroid function while on treatment with this medicine.
- Avoid consuming alcohol while taking this medication.
- Do not stop taking Pethide 250mg Tablet even if you start to feel better. Stopping early can result in treatment failure and in the development of drug-resistant tuberculosis. This can be life-threatening and lead to other serious health risks.
Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Pethide 250mg Tablet.

Pregnancy
CONSULT YOUR DOCTOR
Information regarding the use of Pethide 250mg Tablet during pregnancy is not available. Please consult your doctor.

Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Pethide 250mg Tablet during breastfeeding is not available. Please consult your doctor.

Driving
UNSAFE
Pethide 250mg Tablet may cause side effects which could affect your ability to drive.

Kidney
CAUTION
Pethide 250mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Pethide 250mg Tablet may be needed. Please consult your doctor.

Liver
CAUTION
Pethide 250mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Pethide 250mg Tablet may be needed. Please consult your doctor.

Fact Box
Chemical Class
Pyridines derivatives
Habit Forming
No
Therapeutic Class
ANTI INFECTIVES
Action Class
Mycobacterial cell wall inhibitors-Ethambutol
Related lab tests
References

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User feedback
Tuberculosis (TB)
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Patient concerns
My daughter is given tb medicine even though she is not infected taking these medicine will cause tb???
Dr. Rahul Yadav
Paediatrics
Hello, TB medicines are given only when there is indication of tuberculosis. They are for treating tuberculosis.
Though took vaccines in childhood, the test for TB came positive. Was advised to undergo treatment.physically absolute fit and healthy, is it advisable to take treatment?
Dr. Anshum Aneja Arora
Pulmonology
If sputum is positive for Tb , treatment is absolutely essential. Read more at www.arohealth.com/tuberculosis
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Name: Lupin Ltd
Address: 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India
Address: 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India
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- CBC (Complete Blood Count)
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- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- Glucose - Postprandial
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