R-Cinex 600 Tablet

Written By Dr. Love Sharma, PhD (Pharmacology), PGDPRA

Reviewed By Dr. Varun Gupta, MD Pharmacology, MBBS

Last updated on 12 Nov 2024 | 01:03 AM (IST)

R-Cinex 600 Tablet is a combination medicine used in the treatment of tuberculosis. It prevents the growth of the microorganisms that cause the infection.

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required

₹35.4 MRP ₹36.453% off

General Information

Contains

Rifampicin (600mg)+ Isoniazid (300mg)

Marketer

Lupin Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

R-Cinex 600 Tablet is a prescription medicine and it is to be taken as suggested by the doctor. It should be taken in an empty stomach and take it at a fixed time to ensure better efficacy. Do not consume more than the recommended dose, as this may have harmful effects on your body. If you miss a dose, take it as soon as you remember. The course of the treatment must be completed even if you feel better. Sudden discontinuation of the treatment may affect the potency of the medicine. The medicine may take some to show its effects on the symptoms. However, it is advised to consult the doctor if you feel an aggravation of the condition or if your condition does not improve.

Some common side effects of this medicine are nausea, vomiting, fever, dark-colored urine, sweating, increased saliva, etc. To cope up with the side effects, you should drink plenty of water. If any of the side effects get aggravated, you must consult your doctor immediately. Generally, serious side effects are rare. If you experience any allergic reaction (rashes, itching, swelling, shortness of breath, etc.), you must seek immediate medical help.

Before taking this medicine, you should tell your doctor if you are taking any medicines for any health condition. Patients with liver and kidney ailments must take this medicine with proper consultation and caution. Pregnant or breastfeeding women should also consult with the doctor before taking it. Avoid drinking alcohol as it can cause excessive drowsiness with this medicine. It usually does not impair your ability to drive, but you should not drive if it makes you feel sleepy or dizzy. During the treatment, you must take adequate rest and eat a healthy diet for a faster recovery. While on the medication, your doctor may ask for a few laboratory and diagnostic tests to know the effects of the medicine on your body.

Uses of R-Cinex Tablet

Treatment of Tuberculosis (TB)

Benefits of R-Cinex Tablet

Treatment of Tuberculosis (TB)
R-Cinex 600 Tablet is a combination of medicines that is used to treat tuberculosis, an infectious disease that mainly affects the lungs but can affect other parts of the body as well. It kills as well as stops the growth of infection causing bacteria and helps in treating the infection. Take it in the dose and duration advised by the doctor. Your symptoms may improve before the infection is completely cured. Do not stop taking it without consulting your doctor as doing so may cause the infection to return or worsen. Follow your doctor’s instructions carefully to get maximum benefit.

Side effects of R-Cinex Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of R-Cinex

Dark colored urine
Rash
Vomiting
Jaundice
Fever
Increased liver enzymes
Nausea
Peripheral neuropathy (tingling and numbness of feet and hand)

How to use R-Cinex Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. R-Cinex 600 Tablet is to be taken empty stomach.
Avoid R-Cinex 600 Tablet with tyramine-rich food such as cheese, smoked fish, meats and some types of beer.

How R-Cinex Tablet works

R-Cinex 600 Tablet is a combination of two antibiotics: Rifampicin and Isoniazid, which treats tuberculosis (TB). Rifampicin works by inactivating a bacterial enzyme (RNA-polymerase) which is required by TB bacteria to make essential proteins and to reproduce. Isoniazid prevents these bacteria from forming their own protective covering. Together, they kill the bacteria and eradicate the infection.

Quick tips

You have been prescribed R-Cinex 600 Tablet for the treatment of tuberculosis.
Finish the full course of the medication, even if you feel better. Stopping it early may make the infection come back.
Take it on an empty stomach, preferably at the same time everyday.
It may discolour your urine, sweat, saliva and tears a reddish-orange colour. This is normal and not harmful.
Your doctor may check your liver function before starting treatment and regularly thereafter. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.
Avoid drinking alcohol while taking R-Cinex 600 Tablet as this may increase the risk of side effects on the liver.
Use an alternative or additional contraceptive method (such as condoms or a diaphragm) to prevent pregnancy while you are taking R-Cinex 600 Tablet as it may make hormonal contraceptives such as the pill less effective.
Do not take indigestion remedies (antacids) within at least two hours of taking R-Cinex 600 Tablet.

Safety advice

Alcohol

UNSAFE

Consuming alcohol while taking R-Cinex 600 Tablet may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).

Pregnancy

CONSULT YOUR DOCTOR

R-Cinex 600 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

SAFE IF PRESCRIBED

R-Cinex 600 Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.

Driving

UNSAFE

R-Cinex 600 Tablet may cause side effects which could affect your ability to drive.
R-Cinex 600 Tablet can cause fits, mental health problems and optic neuritis (inflammation of the optic nerve that may cause loss of vision.) This may affect your driving ability.

Kidney

CAUTION

R-Cinex 600 Tablet should be used with caution in patients with kidney disease. Dose adjustment of R-Cinex 600 Tablet may be needed. Please consult your doctor.

Liver

CAUTION

R-Cinex 600 Tablet should be used with caution in patients with liver disease. Dose adjustment of R-Cinex 600 Tablet may be needed. Please consult your doctor.
Use of R-Cinex 600 Tablet is not recommended in patients with severe liver disease.

Frequently asked questions

What is R-Cinex 600 Tablet?

R-Cinex 600 Tablet is a combination of two medicines: Rifampicin and Isoniazid. It is used in the treatment of tuberculosis. Rifampicin works by inactivating a bacterial enzyme (RNA-polymerase) which is required by tuberculosis bacteria to make essential proteins and reproduce. Isoniazid prevents the tuberculosis causing bacteria from forming their own protective covering. Together, they kill the bacteria and eradicate the infection.

What is the most important information I should know about the R-Cinex 600 Tablet?

Take the proper course of drug that has been prescribed to you. Do not stop in between even if you begin to feel better. Avoid alcohol while taking this medicine as it increases the risk of damage to your liver during treatment. Tell your doctor immediately if you experience vision changes, loss of appetite, tiredness, stomach pain, nausea or vomiting, yellow skin or eyes or dark-colored urine.

What is the best time to take R-Cinex 600 Tablet?

Take R-Cinex 600 Tablet exactly as directed by your doctor. It is best to take the medicine on an empty stomach one hour before or two hours after meals.

Does R-Cinex 600 Tablet cause change in urine color/turn urine orange?

Yes, R-Cinex 600 Tablet can change the color of your urine (skin, sweat, saliva, tears and feces) to brownish-red or orange. This effect is not harmful.

Does the use of R-Cinex 600 Tablet make birth control pills ineffective?

Yes, R-Cinex 600 Tablet can make birth control pills less effective. So, ask the doctor about using a birth control method which does not affect your hormone levels (such as a condom, diaphragm and spermicide).

What are the instructions for storage and disposal of R-Cinex 600 Tablet?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Fact Box

Habit Forming

Therapeutic Class

ANTI INFECTIVES

Related lab tests

Complete Blood Count

Erythrocyte Sedimentation Rate

Mycobacterium Tuberculosis DNA PCR - Qualitative

Peripheral Smear Examination

References

User feedback

Patients taking R-Cinex 600 Tablet

Once A Day

99%

Twice A Day

What are you using R-Cinex Tablet for?

Tuberculosis (TB)

92%

Others

Leprosy

How much was the improvement?

Excellent

39%

Average

31%

Poor

30%

What were the side-effects while using R-Cinex 600 Tablet?

Muscle pain

19%

No Side Effect

17%

Vomiting

14%

Skin rash

14%

Nausea

How do you take R-Cinex Tablet?

Empty stomach

74%

With food

22%

With or without food

Please rate R-Cinex 600 Tablet on price

Average

48%

Not Expensive

32%

Expensive

20%

Patient concerns

After having tuberculosis diagnosed she has been recommended to have R cinex EZ 2 tablets daily for 2 months then after 1tablet Risorine for 1 month and now doctor has recommended onceagain to have R cinex EZ 2tables on alternate days what to do.

Dr. Anshum Aneja Arora

Pulmonology

TB treatment is in 2 phases1. Intensive phase where tabs RHZE are given as in your case and in the second phase called continuation phase one one the medicines is stopped nad others continued.Please discuss with your doctor or see another doctor nearby for opinion since , the treatment may have to be modified, read about TB at http://www.arohealth.com/pulmonary-tuberculosis/

I am on ATT for TB treatment from 22 June 2016. Prescribed medicines are R-cinex 600mg, Pzide 1500mg, combutol 1200mg. Doctor has also prescribed Benadon tablet 20mg, rabloc tablet 20mg. I am having rabloc & R-cinex in early morning 5:30 am (empty stomach) & after light breakfast all the remaining tablets. How & when should I take my medicines so that one tablet doesn't contradict other? My liver ALT(SGPT) shot up to 149 on 1 july. asked to stop R-cinex till SGPT doesn't come down. I am want to know which tablet should be taken at which time i.e empty stomach/after light breakfast/lunch? Please help me out here!

Dr. Sfurti Mann

Diabetology

U are taking it correctly.It harms liver sometimes and therefore stopped and re started graduallyU can continue as per your doctor's advise

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Marketer details

Name: Lupin Ltd
Address: 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Provide right medicines

Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose

In accordance with the law

Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945