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Ranomend 500 ER Tablet

Written By Dr. Betina Chandolia, MDS, BDS
Reviewed By Dr. Lalit Kanodia, MBA, MD Pharmacology
Last updated on 10 Nov 2024 | 01:05 AM (IST)
Ranomend 500 ER Tablet is used for the management of angina (heart-related chest pain). It helps to prevent new attacks of angina but does not stop an acute attack, once started. It relieves chest pain by making the heart work more efficiently.
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General Information

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Ranomend 500 ER Tablet image
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Product introduction

Ranomend 500 ER Tablet should be taken in the dose as advised by your doctor, at the same time each day. It should be taken with food to avoid stomach upset. Your doctor will decide how often you should take this medicine. This may change from time to time depending on how well it is working. You should take this medicine regularly to get the most benefit, even if you feel fine. It is preventing future harm. If you stop taking it, your chest pain may come back.

You can improve the health of your heart by making some lifestyle changes such as quitting smoking, cutting down on alcohol, eating well, taking regular exercise, and managing stress. Some common side effects of this medicine include nausea, vomiting, headache, dizziness, constipation, and weakness. Talk to your doctor if these bother you or do not go away.

Ranomend 500 ER Tablet may not suitable for some people. Tell your doctor if you are suffering from any liver or kidney problems. Also let your doctor know all other medications you are using as some may affect, or be affected by this medicine. This medicine is not usually recommended during pregnancy or breastfeeding.

Benefits of Ranomend Tablet ER

Treatment of Angina (heart-related chest pain)
Ranomend 500 ER Tablet reduces the oxygen requirement of the heart and relaxes the heart muscles. It makes sure that your heart is able to perform its functions in the amount of oxygen supply available without causing stress on heart muscles. This makes it less likely that you will suffer chest pain caused by angina. This medicine can help increase your ability to exercise and go about your daily life more easily by reducing the frequency of angina attacks. You should take it regularly and as long as it is prescribed for it to work effectively.

Side effects of Ranomend Tablet ER

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Ranomend
  • Nausea
  • Vomiting
  • Headache
  • Dizziness
  • Constipation
  • Weakness

How to use Ranomend Tablet ER

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Ranomend 500 ER Tablet is to be taken with food.

How Ranomend Tablet ER works

Ranomend 500 ER Tablet is an anti-anginal medication. It works by decreasing the oxygen requirement of the heart by relaxing heart muscle.

Quick tips

  • It should be taken with food to avoid stomach upset.
  • It improves HbA1c and blood sugar levels in diabetes patients.
  • It may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
  • Notify your doctor if you are taking any other medications along with Ranomend 500 ER Tablet
  • It may produce changes in the ECG (QTc interval prolongation). It is recommended to get an ECG done within 1 to 2 weeks of starting the medication.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Ranomend 500 ER Tablet. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Ranomend 500 ER Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Ranomend 500 ER Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Ranomend 500 ER Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney

Kidney

CAUTION
Ranomend 500 ER Tablet should be used with caution in patients with kidney disease. Dose adjustment of Ranomend 500 ER Tablet may be needed. Please consult your doctor.
Use of Ranomend 500 ER Tablet is not recommended in patients with severe kidney disease.
Liver

Liver

CAUTION
Ranomend 500 ER Tablet should be used with caution in patients with liver disease. Dose adjustment of Ranomend 500 ER Tablet may be needed. Please consult your doctor.
Use of Ranomend 500 ER Tablet is not recommended in patients with moderate to severe liver disease.
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Frequently asked questions

Ranomend 500 ER Tablet may cause changes in the electrical activity of the heart which is known as QT prolongation. Your doctor may get regular tests done to check the electrical activity of your heart. Tell your doctor right away if you feel faint, lightheaded or if your heart starts beating irregularly or fast, as these may be symptoms of QT prolongation. Ranomend 500 ER Tablet may also cause kidney failure in patients who already have kidney problems. Therefore, your doctor may need to do tests to check how your kidneys are working.
Urine discoloration could be because of Ranomend 500 ER Tablet. You need not worry if you do not have any other symptoms. However, if it still bothers you, you can talk to your doctor who will advise you further.
Excess of Ranomend 500 ER Tablet can cause nausea, vomiting, lightheadedness, double vision, tiredness, severe tremor, confusion, hallucinations, difficulty in speaking and walking and you can even faint. If you have taken an excess of Ranomend 500 ER Tablet by mistake, call your doctor right away or seek emergency medical care in a nearby hospital.
Yes, it is safe to take the Ranomend 500 ER Tablet and Metoprolol together. Ranomend 500 ER Tablet has minimal effect on blood pressure in patients with angina.
If you are taking metformin along with Ranomend 500 ER Tablet, you have to be careful since Ranomend 500 ER Tablet may increase the levels of metformin in the body which can lead to metformin toxicity. Talk to your doctor who will modify the dose of metformin.
It is recommended not to take simvastatin and Ranomend 500 ER Tablet together because it may cause simvastatin toxicity which may lead to symptoms like muscle weakness and soreness, fatigue, decreased urination, etc. Let your doctor know that you are already taking simvastatin. If it is still necessary to take, then take it exactly as advised by the doctor.

Fact Box

Chemical Class

Acetanilide & piperazine derivative

Habit Forming

No

Therapeutic Class

CARDIAC

Action Class

Late Sodium channel blocker- angina

References

  1. Opie LH, Horowitz JD. Nitrates and Newer Antianginals β-Blocking Agents. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. p. 56
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1200.
  3. Ranolazine. Wooburn Green, Buckinghamshire: A. Menarini Farmaceutica Internazionale SRL; 2008 [revised 22 Nov. 2018]. [Accessed 25 Jan. 2019] (online) Available from:
  4. Ranolazine. Foster City, California: Gilead Sciences, Inc.; 2013. [Accessed 20 Mar. 2019] (online) Available from:
  5. Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:
  6. Ranolazine Sustained Release Tablets [Package Insert]. Ahmedabad, Gujarat: Torrent Pharmaceuticals Ltd.; 2019. [Accessed 25 Jul. 2023] (online) Available from:
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Patient concerns

What is heart attack? When heart attack coming?

Dr. Nabajit Talukdar
Dr. Nabajit Talukdar
Interventional Cardiology
Related to chest pain angina commonly

Chest pain headache virtigo Angina pain

Dr. Nabajit Talukdar
Dr. Nabajit Talukdar
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Get ECG n echo done
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Mendcure Life Sciences Pvt Ltd
Address: R.S. NO.404, FIRST FLOOR, 105 APEX TRADE CENTER, OPP. ITI, REFINERY ROAD, GORWA, VADODARA - 390016

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Ranomend 500 ER Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

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