Sazo 1000mg Tablet

Written By Dr. Betina Chandolia, MDS, BDS

Reviewed By Dr. Lalit Kanodia, MBA, MD Pharmacology

Last updated on 12 Nov 2024 | 01:06 AM (IST)

Sazo 1000mg Tablet is a medicine used to treat various inflammatory conditions of the joints (rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis), skin (psoriasis), and bowel (ulcerative colitis, Crohn’s disease).

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1/2

15 tablets

General Information

Contains

Sulfasalazine (1000mg)

Marketer

Wallace Pharmaceuticals Pvt Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Sazo 1000mg Tablet is to be taken with food. This will help you prevent an upset stomach. You should take it regularly and at the same time each day to get the maximum benefit from it. Keep taking it as recommended by your doctor and complete the dose even if you feel better. Taking it with plenty of water can help you avoid kidney problems such as kidney stones.

Using this medicine may cause some common side effects such as nausea, headache, loss of appetite, vomiting, diarrhea, and gastrointestinal discomfort. You should consult with your doctor if any of these side effects do resolve with time or get worse. Your doctor may help with ways to reduce or prevent these symptoms.

To make sure the medicine is safe for you, before taking this medicine, let your doctor know if you have any problem with your heart, kidneys, or liver. Also, tell your doctor about all the other medicines you are taking. Your doctor may recommend regular blood tests to check your kidney and liver functions, and blood components. Pregnant and breastfeeding mothers should consult with their doctors before taking the medicine.

Uses of Sazo Tablet

Benefits of Sazo Tablet

Treatment of Rheumatoid arthritis
Sazo 1000mg Tablet helps treat inflammation, pain and swelling in rheumatoid arthritis by decreasing the immune system response of the patient. It is given in the dose and frequency that suits your condition. This will be decided by the doctor. You must follow your doctor’s instructions carefully and let your doctor know if you have any bothersome side effects after taking this medicine.

Treatment of Ulcerative colitis
Ulcerative colitis is a disease of the large intestine (colon) and rectum in which the lining of the bowel becomes red and swollen. This can lead to bleeding, frequent diarrhea and abdominal pain. It relieves these symptoms and also helps you to stay well by preventing them from coming back. You should drink plenty of fluids while taking on treatment with this medicine to make sure you stay hydrated.

Treatment of Crohn’s disease
Crohn’s disease is a chronic (long-term) inflammatory disease of the intestines. The most common symptoms are diarrhea and pain in your abdomen. Sazo 1000mg Tablet helps reduce the inflammation, relieve the symptoms, and prevent them from coming back.

Treatment of Ankylosing spondylitis
Ankylosing spondylitis is a rare type of arthritis that affects the spine or larger joints. It usually starts in your lower back and can spread up to your neck or damage joints in other parts of your body. Sazo 1000mg Tablet helps reduce pain, stiffness and swelling in your spine and joints. It helps improve flexibility and prevents disease progression. This will help you lead a better and active life.

Treatment of Psoriatic arthritis
Psoriatic arthritis (PsA) is a type of inflammatory arthritis that affects some individuals with psoriasis, causing joint pain, swelling, and stiffness alongside skin symptoms. Sazo 1000mg Tablet has anti-inflammatory properties that help reduce joint pain, swelling, and stiffness. This medicine can also slow down the progression of joint damage associated with PsA. Additionally, it can help improve skin symptoms in individuals with both psoriasis and arthritis.

Side effects of Sazo Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Sazo

Diarrhea
Gastrointestinal discomfort
Headache
Loss of appetite
Nausea
Oligospermia (low sperm count)
Vomiting

How to use Sazo Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sazo 1000mg Tablet is to be taken with food.

How Sazo Tablet works

Sazo 1000mg Tablet is a Disease Modifying Anti-Rheumatoid Drug (DMARD). It works by suppressing the overactivity of the immune system in autoimmune diseases and blocks the chemical messengers that cause inflammation (swelling).

All substitutes for Sazo 1000mg Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Take it with food to avoid an upset stomach.
It may take 6-8 weeks for Sazo 1000mg Tablet to work. Keep taking it as prescribed.
Drink plenty of fluids while taking Sazo 1000mg Tablet in order to avoid kidney problems such as kidney stones.
It may cause a deficiency of folic acid. Take the supplements as suggested by the doctor.
Do not take Sazo 1000mg Tablet if you are allergic to sulfa drugs or aspirin.
It may discolour your skin, urine, saliva and tears an orange/yellow colour. This is normal and not harmful.
Regular blood tests to monitor your liver function, kidney function, and the levels of your blood components are required while taking this medicine.
Do not stop taking the medication suddenly without talking to your doctor.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Sazo 1000mg Tablet.

Pregnancy

SAFE IF PRESCRIBED

Sazo 1000mg Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Breast feeding

CONSULT YOUR DOCTOR

Sazo 1000mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

SAFE

Sazo 1000mg Tablet does not usually affect your ability to drive.

Kidney

CAUTION

Sazo 1000mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Sazo 1000mg Tablet may be needed. Please consult your doctor.
Regular monitoring of kidney function tests is advisable while you are taking this medicine.

Liver

UNSAFE

Sazo 1000mg Tablet is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.

Frequently asked questions

Is Sazo 1000mg Tablet a steroid or a painkiller?

Sazo 1000mg Tablet is neither a steroid nor a painkiller. It is an anti-inflammatory medicine. It is used to treat and manage ulcerative colitis and Crohn's disease in which the intestines become inflamed (swelling of intestines). It is also used to treat rheumatoid arthritis (painful joint disease).

What is Sazo 1000mg Tablet and what is it used for?

Sazo 1000mg Tablet belongs to a group of medicines called aminosalicylates. It is an anti-inflammatory disease and is used to treat bowel inflammation, diarrhea (stool frequency), rectal bleeding, and abdominal pain in patients with ulcerative colitis and Crohn’s disease. In rheumatoid arthritis, it helps prevent damage to the joints and works slowly to reduce swelling and stiffness in your joints.

I have been prescribed Sazo 1000mg Tablet for rheumatoid arthritis. When can I expect the pain in joints to be better?

Sazo 1000mg Tablet does not work right away. It takes about 6 to 12 weeks to deliver the full effect.You may start feeling better in 4 weeks after starting Sazo 1000mg Tablet, but it can vary from person to person and some of the patients may notice improvement after 3 months. Consumption of medicine should not be stopped without consulting your doctor.

For how long do I need to take Sazo 1000mg Tablet?

If you are able to tolerate Sazo 1000mg Tablet which means the side effects do not bother you, then you have to continue Sazo 1000mg Tablet till the disease remains in remission. It is better to take Sazo 1000mg Tablet for the prescribed period.

Does the use of Sazo 1000mg Tablet for the treatment of arthritis affect the kidney function?

Though it is uncommon, Sazo 1000mg Tablet may affect your kidney function. Therefore, it is important that your kidney function remains normal before you start taking Sazo 1000mg Tablet. If during treatment with Sazo 1000mg Tablet your kidney functions become abnormal, you should consult your doctor.

Do I need to get any blood tests done while on Sazo 1000mg Tablet therapy?

Your doctor will advise you blood tests to check your blood cell counts and your kidney function before starting your treatment and regularly during treatment. The tests should also be done to measure substances produced by your liver known as enzymes (liver function tests) and urine for protein and blood before you start treatment and at regular intervals.

Can Sazo 1000mg Tablet affect my fertility?

Decreased sperm count and infertility have been reported in some males. These may disappear once Sazo 1000mg Tablet is discontinued.

Can I take azathioprine along with Sazo 1000mg Tablet?

You should avoid using Sazo 1000mg Tablet with azathioprine since there are chances of decrease in blood cell count, which can be a serious side effect.

Fact Box

Chemical Class

Aminosalicylic Acids Derivative

Habit Forming

Therapeutic Class

GASTRO INTESTINAL

Action Class

Disease Modifying Anti-Rheumatoid Drugs (DMARDs)- Non biologics

Related lab tests

Anti Neutrophilic Cytoplasmic Antibody - P

Anti Saccharomyces Cerevisiae (ASCA), IgA

Anti Saccharomyces Cerevisiae (ASCA), IgG

C- Reactive Protein Quantitative

Erythrocyte Sedimentation Rate

HLA - B27, PCR

Rheumatoid Factor - Agglutination

Rheumatoid Factor - Turbidometry

Rheumatoid Factor IgG Antibody

References

Furst DE, Ulrich RW, Varkey-Altamirano C. Nonsteroidal Anti-Inflammatory Drugs, Disease Modifying Antirheumatic Drugs, Nonopioids Analgesics, & Drugs Used in Gout. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 632-33.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1295-97.
Sulfasalazine. Sandwich, Kent: Pfizer Limited; 2010 [revised Feb. 2014]. [Accessed 23 Jan. 2019] (online) Avaialble from:
Sulfasalazine. Uppsala, Sweden: Recipharm, Uppsala; 2018. [Accessed 18 Jun. 2019] (online) Available from:
Sulfasalazine. New York, New York: Pharmacia & Upjohn Co.; 2014. [Accessed 18 Jun. 2019] (online) Available from:
Oxford Radcliffe Hospitals: NHS Trust. Sulfasalazine. [Accessed 18 Jun. 2018] (online) Available from:
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 02 Apr. 2019] (online) Available from:
Choi J, Fenando A. Sulfasalazine. [Updated 2022 Nov 11]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023. [Accessed 06 Aug. 2023]. (online) Available from:
National Health Service. Sulfasalazine. [Accessed 06 Aug. 2023]. (online) Available from:
Versus Arthritis. Sulfasalazine [Information Booklet]. [Accessed 06 Aug. 2023]. (online) Available from:

Patient concerns

Having severe ankylosing spondylitis Sazo 1000 mg along with calcijoint tab one perday going on. Still problem persists. Please suggest more on this

Dr. Akshat Goel

Orthopaedics

Take sazo twice dailyAnd take Tab Tolpazen twice daily for 5 daysApply Dynapar QPS spray

Suffering from severe lower back pain since 6 years. As per MRI it is lumbar spondylosis,but Doctor told that it is one of the types of arthritis in which bridge is getting formed on spine Is there any permanent solution .at present taking Sazo 500 twice a day

Dr. Akshat Goel

Orthopaedics

It's called Ankylosing spondylitis". no permanent cure for this All you need to do is to exercise each and every joint of your body regularly "Along with the medication

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Wallace Pharmaceuticals Pvt Ltd
Address: Wallace Pharmaceuticals Pvt. Ltd., 3rd Floor, Dempo Trade Centre Bldg., Patto Plaza, EDC Complex, Panaji 403001, Goa, India.

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Sazo 1000mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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