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Solonex DT Tablet

Written By Dr. Love Sharma, PhD (Pharmacology), PGDPRA
Reviewed By Dr. Varun Gupta, MD Pharmacology, MBBS
Last updated on 12 Nov 2024 | 01:08 AM (IST)
Solonex DT Tablet is an antibiotic used for the treatment and prevention of tuberculosis (TB) and inactive (latent) TB (a serious infection caused by bacteria that affects the lungs and in certain cases other parts of the body). It works by killing the bacteria that cause tuberculosis.
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General Information

Contains

Isoniazid (100mg)

Marketer

Macleods Pharmaceuticals Pvt Ltd

Storage

Store below 30°C
The content is shown in English
Solonex DT Tablet image
Solonex DT Tablet image
Solonex DT Tablet image
Solonex DT Tablet image
Solonex DT Tablet image

Product introduction

Solonex DT Tablet should be used in the dose and duration as advised by your doctor. It is to be taken on an empty stomach. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early can result in treatment failure and increase the side effects too. Do not take a double dose to make up for a missed dose. Simply take the next dose as planned.

Some common side effects of this medicine include tingling and numbness of feet and hand (peripheral neuropathy). Inform your doctor if you notice signs of jaundice, i.e., yellowing of eyes or skin, dark urine, stomach pain, or joint pain. You may also develop hepatitis (viral infection of the liver) or increased liver enzymes as side effects of this medicine. Please consult your doctor, as these side effects require medical attention and need dose modification.

Your doctor may monitor your liver function while on treatment with this medicine. Avoid drinking alcohol as this may have additional adverse effects on the liver. Pregnant or breastfeeding women should consult their doctor before using this medicine.

Uses of Solonex Tablet DT

Benefits of Solonex Tablet DT

Tuberculosis (TB)
Solonex DT Tablet is used to treat tuberculosis, an infectious disease that mainly affects the lungs but can affect other parts of the body as well. It kills and stops the growth of infection causing bacteria and helps in treating the infection. Take it in the dose and duration advised by the doctor. Your symptoms may improve before the infection is completely cured. Do not stop taking it without consulting your doctor as doing so may cause the infection to return or worsen. Follow your doctor’s instructions carefully to get maximum benefit.

Side effects of Solonex Tablet DT

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Solonex
  • Peripheral neuropathy (tingling and numbness of feet and hand)
  • Hepatitis (viral infection of liver)
  • Skin rash
  • Lethargy
  • Increased liver enzymes

How to use Solonex Tablet DT

Take this medicine in the dose and duration as advised by your doctor. Dissolve it in a glass of water before taking it. Solonex DT Tablet is to be taken empty stomach.
Avoid Solonex DT Tablet with tyramine-rich food such as cheese, smoked fish, meats and some types of beer.

How Solonex Tablet DT works

Solonex DT Tablet is an antibiotic. It works by killing the bacteria that causes tuberculosis.

Quick tips

  • Your doctor has prescribed Solonex DT Tablet to cure your infection and improve symptoms.
  • It is best taken on an empty stomach.
  • You must also take a vitamin B6 supplement while on Solonex DT Tablet.
  • Tell your doctor immediately if you experience vision changes, loss of appetite, tiredness, stomach pain, nausea or vomiting, yellow skin or eyes or dark-colored urine.

Safety advice

Alcohol

Alcohol

UNSAFE
Consuming alcohol while taking Solonex DT Tablet may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Solonex DT Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding

Breast feeding

SAFE IF PRESCRIBED
Solonex DT Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving

Driving

UNSAFE
Solonex DT Tablet may cause side effects which could affect your ability to drive.
Solonex DT Tablet can cause fits, mental health problems and optic neuritis (inflammation of the optic nerve that may cause loss of vision.) This may affect your driving ability.
Kidney

Kidney

SAFE IF PRESCRIBED
Solonex DT Tablet is safe to use in patients with kidney disease. No dose adjustment of Solonex DT Tablet is recommended.
However, talk to your doctor if you have any underlying kidney disease.
Liver

Liver

CAUTION
Solonex DT Tablet should be used with caution in patients with liver disease. Dose adjustment of Solonex DT Tablet may be needed. Please consult your doctor.
Use of Solonex DT Tablet is not recommended in patients with severe liver disease.
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Frequently asked questions

Solonex DT Tablet is an antibiotic used in the prevention and treatment of tuberculosis or TB (a serious infection caused by bacteria that affects the lungs and in certain cases other parts of the body)
Solonex DT Tablet is a primary antibiotic used for treatment of tuberculosis. Do not confuse it with chemotherapy or chemo drugs used for the treatment of cancer
Solonex DT Tablet is a bacteriostatic antibiotic. It stops or suppresses growth of tuberculosis causing bacteria by interfering with the formation of protective outer covering (cell wall) which is essential for their growth
Yes. Solonex DT Tablet is safe if used at prescribed doses for the prescribed duration as advised by your doctor
Solonex DT Tablet has very weak inhibitory activity on enzymes monoamine oxidases (MAO); however it is not used as a monoamine oxidase inhibitor (MAOI)
No. The chemical structure and mechanism of action of Solonex DT Tablet is different from sulfa drugs
Solonex DT Tablet is an inhibitor (decreases activity) of an important liver enzyme system that is responsible for the final processing and elimination of several drugs from the body
There no known serious drug interactions of isoniazid with ibuprofen, paracetamol (trade name: Tylenol), naproxen (trade name: Aleve), amoxicillin or any active drug present in Nyquil or Mucinex. Please inform your doctor about all the medication you are currently taking to avoid interactions that may reduce effectiveness of any treatment or aggravate side effects
Changes in body weight (gain/loss), hair loss, diarrhea or changes in menstruation are not among the known side effects of Solonex DT Tablet. You may experience few of these side effects while on multi drug (including Solonex DT Tablet) treatment for tuberculosis
You may experience unusual tiredness, constipation or acne while on treatment with Solonex DT Tablet. Please inform your doctor about all the medication you are currently taking to avoid interactions that may reduce effectiveness of any treatment or aggravate side effects
Solonex DT Tablet has no known interaction with commonly used oral contraceptives (birth control pills). However, multidrug treatment for tuberculosis contains active drug rifampin that decreases the effectiveness of oral contraceptives and hampers birth control.

Fact Box

Chemical Class

Nicotinic acid derivatives

Habit Forming

No

Therapeutic Class

ANTI INFECTIVES

Action Class

Mycolic acid inhibitors- INH

Related lab tests

Complete Blood Count

Erythrocyte Sedimentation Rate

Mycobacterium Tuberculosis DNA PCR - Qualitative

Peripheral Smear Examination

References

  1. Gumbo T. Chemotherapy of Tuberculosis, Mycobacterium Avium Complex Disease, and Leprosy. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1555-558.
  2. Chambers HF, Deck DH. Antimycobacterial Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 824-25.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 741-42.
  4. Isoniazid. Nottingham, Nottinghamshire: Boots Contract Manufacturing; 2015. [Accessed 01 Apr. 2019] (online) Available from:
  5. Drugs.com. Isoniazid. [Accessed 01 Apr. 2019] (online) Available from:
  6. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 29 Mar. 2019] (online) Available from:
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User feedback

Once A Day
90%
Thrice A Day
4%
Twice A Day
4%
Alternate Day
2%
Tuberculosis (TB)
83%
Others
17%
Average
42%
Poor
42%
Excellent
17%
No Side Effect
50%
Increased liver enzymes
50%
With food
100%
Not Expensive
100%

Patient concerns

Sir,I'm a tb patient ,doctor give me medicine,but i don't know how i take this medicine ,before meal or after meal please help me This is my medicine Solonex 300 mg R cin 600mg Pyzina 1500mg combutol 1000mg Pyridoxin 40mg

Dr. Pushkar Mani
Dr. Pushkar Mani
Physician
That u have to ask ur and also u visit dots centre for tuberculosis tratment

My 7 months child diagnosed with woofing cough.Doctor prescribed Solonex DT half tab for 30 days Health Ok drops 2.5 ml at morning Montemac L at evening Is this prescription is good for him.

Dr. Gopal Samdani
Dr. Gopal Samdani
Paediatrics
Please share contents of medicine you are takingPlease share the blood reports you have done which suggest this diagnosis.
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Macleods Pharmaceuticals Pvt Ltd
Address: Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, INDIA.

Vendor Details

Country of origin: India

Lab tests offered by us

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