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Desmopressin

Written By Dr. Radhika DuaReviewed By Dr. Shilpa Garcha
Last updated 08 Nov 2024 | 06:36 AM (UTC)

Desmopressin Uses

Desmopressin is used in the treatment of bleeding esophageal varices, diabetes insipidus and bed-wetting.

How Desmopressin works

Desmopressin is a synthetic form of vasopressin (natural hormone that balances water). It works by causing reabsorption of water from the kidneys which controls excessive thirst and urination in diabetes insipidus. It also helps decrease night-time urine production and bedwetting in children. In addition to these, it reduces bleeding episodes by promoting the release of blood clotting factors.

Common side effects of Desmopressin

Xerostomia
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Expert advice for Desmopressin

  • You have been prescribed Desmopressin for the treatment of diabetes insipidus and/or bed-wetting.
  • Limit the amount of fluids you drink with this medication.
  • Desmopressin can cause low sodium levels in your body. Get regular blood tests done to monitor the levels.
  • Inform your doctor if you develop an infection, fever, diarrhea, or vomiting.
  • Talk to your doctor if you have sudden weight gain or swelling in your arms and legs that does not go away.
     

Frequently asked questions for Desmopressin

No, Desmopressin does not cure bedwetting, but it helps control bedwetting. It works by replacing a hormone (vasopressin) that is normally produced in the body to help balance the amount of water and salt.
No, Desmopressin itself does not cause weight gain. Desmopressin may cause fluid overload which may in turn cause weight gain. Fluid overload is a serious side effect and you should immediately contact your doctor if you experience headache, nausea, vomiting, restlessness, tiredness, loss of appetite, sleepiness, confusion and muscle cramps.
No, Desmopressin is not a diuretic. It is a hormone which helps lower urine output in patients with diabetes insipidus and helps control bedwetting in children. It works by reducing the amount of urine produced by the kidneys, thereby reducing the frequency of urination.
Follow all the instructions given by your doctor strictly. Restrict water intake after taking Desmopressin as drinking too much water can lead to fluid overload, which is a serious side effect. Try not to swallow water while swimming.
Desmopressin is usually prescribed for 3 months for bedwetting. After 3 months, your doctor will stop the medicine for a week to assess whether your child still needs Desmopressin or not.